DE69620757T2 - In yarrowia funktionell aktive stromaufwärts-liegende aktivatorsequenzen und rekombinante promotersequenzen und vektoren die diese enthalten - Google Patents

In yarrowia funktionell aktive stromaufwärts-liegende aktivatorsequenzen und rekombinante promotersequenzen und vektoren die diese enthalten

Info

Publication number
DE69620757T2
DE69620757T2 DE69620757T DE69620757T DE69620757T2 DE 69620757 T2 DE69620757 T2 DE 69620757T2 DE 69620757 T DE69620757 T DE 69620757T DE 69620757 T DE69620757 T DE 69620757T DE 69620757 T2 DE69620757 T2 DE 69620757T2
Authority
DE
Germany
Prior art keywords
sequences
yarrowia
vectors containing
recombinant promoter
functionally active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69620757T
Other languages
English (en)
Other versions
DE69620757D1 (de
Inventor
Catherine Madzak
Sylvie Blanchin-Roland
Claude Gaillardin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST NAT AGRONOMIQUE PARIS GRI
Institut National de la Recherche Agronomique INRA
Original Assignee
INST NAT AGRONOMIQUE PARIS GRI
Institut National de la Recherche Agronomique INRA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST NAT AGRONOMIQUE PARIS GRI, Institut National de la Recherche Agronomique INRA filed Critical INST NAT AGRONOMIQUE PARIS GRI
Publication of DE69620757D1 publication Critical patent/DE69620757D1/de
Application granted granted Critical
Publication of DE69620757T2 publication Critical patent/DE69620757T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
DE69620757T 1995-06-08 1996-06-06 In yarrowia funktionell aktive stromaufwärts-liegende aktivatorsequenzen und rekombinante promotersequenzen und vektoren die diese enthalten Expired - Lifetime DE69620757T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95401322A EP0747484A1 (de) 1995-06-08 1995-06-08 Aufwährts-aktivierungssequenzen und rekombinante Promotorsequenzen die in Yarrowia funktionell sind, und Vektoren die sie enthalten
PCT/IB1996/000562 WO1996041889A1 (en) 1995-06-08 1996-06-06 Upstream activator sequences and recombinant promoter sequences functional in yarrowia and vectors containing them

Publications (2)

Publication Number Publication Date
DE69620757D1 DE69620757D1 (de) 2002-05-23
DE69620757T2 true DE69620757T2 (de) 2002-11-28

Family

ID=8221496

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69620757T Expired - Lifetime DE69620757T2 (de) 1995-06-08 1996-06-06 In yarrowia funktionell aktive stromaufwärts-liegende aktivatorsequenzen und rekombinante promotersequenzen und vektoren die diese enthalten

Country Status (9)

Country Link
US (1) US6083717A (de)
EP (2) EP0747484A1 (de)
JP (1) JP4346681B2 (de)
AT (1) ATE216428T1 (de)
AU (1) AU5776296A (de)
CA (1) CA2221468C (de)
DE (1) DE69620757T2 (de)
DK (1) DK0832258T3 (de)
WO (1) WO1996041889A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6610839B1 (en) 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
US7053265B2 (en) 2000-10-02 2006-05-30 The Board Of Trustees Operating Michigan State University Application of bi-directional promoters for modification of gene expression
US7459546B2 (en) 2003-06-25 2008-12-02 E.I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase regulatory sequences for gene expression in oleaginous yeast
US7259255B2 (en) 2003-06-25 2007-08-21 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
WO2005049805A2 (en) 2003-11-14 2005-06-02 E.I. Dupont De Nemours And Company Fructose-bisphosphate aldolase regulatory sequences for gene expression in oleaginous yeast
AU2006227165B2 (en) 2005-03-18 2011-11-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
FR2927089B1 (fr) * 2008-02-05 2011-03-25 Inst Nat De La Rech Agronomique Inra Procede d'integration ciblee de multicopies d'un gene d'interet dans une souche de yarrowia
DK2310517T3 (en) * 2008-07-11 2016-06-06 Inst Nat De La Rech Agronomique (Inra) Novel mutant yeast strains having a capability to accumulate a large amount of lipids
WO2011063350A2 (en) 2009-11-23 2011-05-26 Cibus Oils, Llc Methods and compositions for producing squalene using yeast
EP2327776A1 (de) * 2009-11-30 2011-06-01 Institut National De La Recherche Agronomique Verfahren zur Herstellung von sehr langkettigen Fettsäuren durch Gärung mit einer rekombinanten Yarrowia-Spezies
FR2962133B1 (fr) 2010-07-01 2014-09-12 Agronomique Inst Nat Rech Optimisation de la synthese et de l'accumulation de lipides
FR3005317B1 (fr) 2013-05-02 2016-03-18 Agronomique Inst Nat Rech Levures mutantes capables de produire un acide gras inhabituel
US20170145449A1 (en) 2014-06-11 2017-05-25 Institut National De La Recherche Agronomique Improved lipid accumulation in Yarrowia lipolytica strains by overexpression of hexokinase and new strains thereof
IL241841B (en) 2014-09-30 2019-09-26 Univ Free State Production of proteins for human and animal health using yarrowia lipolytica
FR3028527A1 (fr) 2014-11-13 2016-05-20 Pivert Identification de facteurs de transcription de yarrowia lipolytica
WO2016075314A1 (fr) 2014-11-13 2016-05-19 Institut National De La Recherche Agronomique Identification de facteurs de transcription de yarrowia lipolytica affectant la production de proteines
EP3085788A1 (de) 2015-04-23 2016-10-26 Institut National De La Recherche Agronomique Mutanter hefestamm mit fähigkeit zum abbau von cellobiose
EP3106520A1 (de) 2015-06-17 2016-12-21 Institut National De La Recherche Agronomique Mutanter yarrowia-stamm mit fähigkeit zum abbau von galaktose
US20190136278A1 (en) 2016-05-10 2019-05-09 Institut National De La Recherche Agronomique Mutant yeast strains with enhanced production of erythritol or erythrulose
EP3348647A1 (de) 2017-01-13 2018-07-18 Institut National De La Recherche Agronomique Mutanter hefestamm mit fähigkeit zur produktion von fettsäuren mittlerer länge
EP3360956A1 (de) 2017-02-10 2018-08-15 Institut National De La Recherche Agronomique Zum abbau von cellulose fähiger, mutanter hefestamm
EP3404104A1 (de) 2017-05-18 2018-11-21 Institut National De La Recherche Agronomique (INRA) Induzierbarer promoter für genexpression und synthetische biologie

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN163393B (de) 1983-10-06 1988-09-17 Pfizer
US4937189A (en) 1985-10-18 1990-06-26 Pfizer Inc. Expression and secretion of heterologous proteins by Yarrowia lipolytica transformants

Also Published As

Publication number Publication date
DE69620757D1 (de) 2002-05-23
EP0832258A1 (de) 1998-04-01
EP0747484A1 (de) 1996-12-11
JPH11507550A (ja) 1999-07-06
EP0832258B1 (de) 2002-04-17
CA2221468C (en) 2010-07-27
ATE216428T1 (de) 2002-05-15
US6083717A (en) 2000-07-04
AU5776296A (en) 1997-01-09
JP4346681B2 (ja) 2009-10-21
WO1996041889A1 (en) 1996-12-27
CA2221468A1 (en) 1996-12-27
DK0832258T3 (da) 2002-08-12

Similar Documents

Publication Publication Date Title
DE69620757D1 (de) In yarrowia funktionell aktive stromaufwärts-liegende aktivatorsequenzen und rekombinante promotersequenzen und vektoren die diese enthalten
IL96907A0 (en) Proteins produced by human lymphocytes,a dna sequence coding for said proteins and their pharmaceutical and biological application
EP0614977A3 (en) Huntingtin dna, protein and uses thereof.
HUT77049A (hu) Katepszin-02-fehérjék, -nukleinsavak és -ellenanyagok
IL101024A0 (en) Process for the activation of recombinant proteins
ATE199377T1 (de) Protein mit cytokinaktivität, rekombinant-dns, expressionsvektor und wirtszellen zu seiner herstellung
AU2197392A (en) Hepatitis C virus from C-100-3 and env/core regions
ZA965565B (en) Novel peptides derived from human heat shock protein 60 for treatment of diabetes, compositions, methods and kits.
PL322333A1 (en) Dna encoding human papilloma viruses of type 18
GB9606040D0 (en) Active peptide
IL122606A (en) (S)-hydroxa-nitrile-lyase
DE69533626D1 (de) Tioredioxine h aus zwig und hart-weizen und ähnliche proteine, diese kodierende dna-fragmente und verfahren zu ihrer herstellung
ATE372787T1 (de) Atelocollagen enthaltende gen-zusammensetzungen
AU2415599A (en) Rantes mutants and therapeutic applications thereof
DE69315730D1 (de) Verfahren zur Herstellung von Peptiden und neue Zwischenverbindungen dazu
EP0490383A3 (en) Peptides of the hiv-gag protein, their preparation and use
PT788549E (pt) Sequencias reguladoras de acidos nucleicos e utilizacoes
AU5327198A (en) Nucleotide sequence coding for a flavin-containing monooxygenase, corresponding protein and their applications in the fields of diagnosis and therapy
DE69030293D1 (de) Neue Peptide, deren Intermediate, Verfahren zu deren Herstellung, antiallergische Agenzien, Vasodilatoren und Immunoregulatoren
HU9600500D0 (en) Genes from actinoplanes sp. for biosynthesis of acarbose, process for their isolation and their use
HU9402646D0 (en) Anomere fluoro-ribosyl-amines
SE9302168D0 (sv) Ryggsaeck med ihopfaellbar sittstol

Legal Events

Date Code Title Description
8364 No opposition during term of opposition