DE69618663D1 - O-carbamoyl-phenylalaninol-zusammensetzungen und ihre pharmazeutisch anwendbaren salzen - Google Patents
O-carbamoyl-phenylalaninol-zusammensetzungen und ihre pharmazeutisch anwendbaren salzenInfo
- Publication number
- DE69618663D1 DE69618663D1 DE69618663T DE69618663T DE69618663D1 DE 69618663 D1 DE69618663 D1 DE 69618663D1 DE 69618663 T DE69618663 T DE 69618663T DE 69618663 T DE69618663 T DE 69618663T DE 69618663 D1 DE69618663 D1 DE 69618663D1
- Authority
- DE
- Germany
- Prior art keywords
- phenylalaninol
- carbamoyl
- compositions
- applicable salts
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/24—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/KR1996/000174 WO1998015526A1 (en) | 1996-10-10 | 1996-10-10 | O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same |
| CN96198889A CN1076016C (zh) | 1996-10-10 | 1996-10-10 | O－氨基甲酰基－苯丙胺醇化合物、其药学上有用的盐和它们的制备方法 |
| CA002240060A CA2240060C (en) | 1996-10-10 | 1996-10-10 | O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69618663D1 true DE69618663D1 (de) | 2002-02-28 |
| DE69618663T2 DE69618663T2 (de) | 2002-08-14 |
Family
ID=27170728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69618663T Expired - Lifetime DE69618663T2 (de) | 1996-10-10 | 1996-10-10 | O-carbamoyl-phenylalaninol-zusammensetzungen und ihre pharmazeutisch anwendbaren salzen |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0873308B1 (de) |
| JP (1) | JP4068154B2 (de) |
| CN (1) | CN1076016C (de) |
| CA (1) | CA2240060C (de) |
| DE (1) | DE69618663T2 (de) |
| DK (1) | DK0873308T3 (de) |
| ES (1) | ES2170878T3 (de) |
| PT (1) | PT873308E (de) |
| WO (1) | WO1998015526A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4565747B2 (ja) * | 1999-02-04 | 2010-10-20 | エスケー ホルディングス カンパニー リミテッド | テトラヒドロイソキノリンアルカノール誘導体及びそれを含む薬学的組成物 |
| US20050080268A1 (en) * | 2003-10-08 | 2005-04-14 | Yong-Moon Choi | Process of preparing O-carbamoyl compounds in the presence of active amine group |
| PL1890684T3 (pl) | 2005-06-08 | 2014-05-30 | Sk Biopharmaceuticals Co Ltd | Leczenie zaburzeń snu i czuwania |
| MX2009003926A (es) * | 2006-10-13 | 2009-06-26 | Janssen Pharmaceutica Nv | Composiciones de fenilalquilamino-carbamato. |
| AU2010270971B2 (en) * | 2009-06-22 | 2015-08-20 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating or preventing fatigue |
| US8232315B2 (en) * | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
| KR101783632B1 (ko) | 2009-11-06 | 2017-10-10 | 에스케이바이오팜 주식회사 | 주의력 결핍/과잉행동 장애(ａｄｈｄ)의 치료 방법 |
| RU2557533C2 (ru) * | 2009-11-06 | 2015-07-20 | Ск Биофармасъютиклс Ко., Лтд. | Способы лечения синдрома фибромиалгии |
| US9610274B2 (en) * | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
| US8623913B2 (en) | 2010-06-30 | 2014-01-07 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating restless legs syndrome |
| ES2927675T3 (es) | 2013-03-13 | 2022-11-10 | Jazz Pharmaceuticals Ireland Ltd | Tratamiento de la cataplexia |
| PL3021838T3 (pl) | 2013-07-18 | 2021-03-08 | Jazz Pharmaceuticals Ireland Limited | Leczenie otyłości |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| AU2018278332B2 (en) | 2017-06-02 | 2022-05-19 | Jazz Pharmaceuticals Ireland Limited | Methods and compositions for treating excessive sleepiness |
| RU2020108634A (ru) * | 2017-07-31 | 2021-09-02 | Джаз Фармасьютикалз Айрлэнд Лимитед | Аналоги карбамоилфенилаланинола и способы их применения |
| CN110655500B (zh) * | 2018-06-28 | 2020-12-08 | 浙江京新药业股份有限公司 | 氨基甲酸酯衍生物及其制备方法和用途 |
| WO2021161232A1 (en) * | 2020-02-12 | 2021-08-19 | Lupin Limited | Process for preparation of solriamfetol and intermediates thereof |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
| KR102390194B1 (ko) | 2020-08-03 | 2022-04-25 | 셀라이온바이오메드 주식회사 | 페닐알킬 카바메이트 화합물을 포함하는 Kca3.1채널 매개질환 치료용 조성물 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2937119A (en) * | 1959-06-11 | 1960-05-17 | Carter Prod Inc | Nu-monosubstituted-2, 2-dialkyl-1, 3-propanediol dicarbamates |
| KR0173862B1 (ko) * | 1995-02-11 | 1999-04-01 | 조규향 | O-카바모일-(d)-페닐알라닌올 화합물과 그의 약제학적으로 유용한 염 및 이들의 제조방법 |
-
1996
- 1996-10-10 WO PCT/KR1996/000174 patent/WO1998015526A1/en active IP Right Grant
- 1996-10-10 EP EP96935553A patent/EP0873308B1/de not_active Expired - Lifetime
- 1996-10-10 ES ES96935553T patent/ES2170878T3/es not_active Expired - Lifetime
- 1996-10-10 JP JP51740598A patent/JP4068154B2/ja not_active Expired - Lifetime
- 1996-10-10 DE DE69618663T patent/DE69618663T2/de not_active Expired - Lifetime
- 1996-10-10 PT PT96935553T patent/PT873308E/pt unknown
- 1996-10-10 DK DK96935553T patent/DK0873308T3/da active
- 1996-10-10 CN CN96198889A patent/CN1076016C/zh not_active Expired - Lifetime
- 1996-10-10 CA CA002240060A patent/CA2240060C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2240060A1 (en) | 1998-04-16 |
| EP0873308B1 (de) | 2002-01-02 |
| JP4068154B2 (ja) | 2008-03-26 |
| PT873308E (pt) | 2002-06-28 |
| CN1076016C (zh) | 2001-12-12 |
| CA2240060C (en) | 2007-07-17 |
| DE69618663T2 (de) | 2002-08-14 |
| EP0873308A1 (de) | 1998-10-28 |
| CN1204316A (zh) | 1999-01-06 |
| ES2170878T3 (es) | 2002-08-16 |
| JP2000502364A (ja) | 2000-02-29 |
| WO1998015526A1 (en) | 1998-04-16 |
| DK0873308T3 (da) | 2002-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SK HOLDINGS CO., LTD., SEOUL, KR |
|
| R082 | Change of representative |
Ref document number: 873308 Country of ref document: EP Representative=s name: BEETZ & PARTNER PATENT- UND RECHTSANWAELTE, 80538 |