DE69608699T2 - Fluorsubstituierte benzoylpropionsaürederivate - Google Patents

Fluorsubstituierte benzoylpropionsaürederivate

Info

Publication number
DE69608699T2
DE69608699T2 DE69608699T DE69608699T DE69608699T2 DE 69608699 T2 DE69608699 T2 DE 69608699T2 DE 69608699 T DE69608699 T DE 69608699T DE 69608699 T DE69608699 T DE 69608699T DE 69608699 T2 DE69608699 T2 DE 69608699T2
Authority
DE
Germany
Prior art keywords
pct
fluorosubstituted
acid derivatives
benzoylpropionic acid
sec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69608699T
Other languages
English (en)
Other versions
DE69608699D1 (de
Inventor
Mario Varasi
Antonio Giordani
Carmela Speciale
Massimo Cini
Alberto Bianchetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia and Upjohn SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn SpA filed Critical Pharmacia and Upjohn SpA
Application granted granted Critical
Publication of DE69608699D1 publication Critical patent/DE69608699D1/de
Publication of DE69608699T2 publication Critical patent/DE69608699T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69608699T 1995-10-20 1996-10-04 Fluorsubstituierte benzoylpropionsaürederivate Expired - Fee Related DE69608699T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9521486.2A GB9521486D0 (en) 1995-10-20 1995-10-20 Fluoro-substituted benzoylpropionic acid derivatives
PCT/EP1996/004321 WO1997015550A1 (en) 1995-10-20 1996-10-04 Fluoro-substituted benzoylpropionic acid derivatives

Publications (2)

Publication Number Publication Date
DE69608699D1 DE69608699D1 (de) 2000-07-06
DE69608699T2 true DE69608699T2 (de) 2000-11-23

Family

ID=10782602

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69608699T Expired - Fee Related DE69608699T2 (de) 1995-10-20 1996-10-04 Fluorsubstituierte benzoylpropionsaürederivate

Country Status (14)

Country Link
US (1) US5973006A (de)
EP (1) EP0862551B1 (de)
JP (1) JPH11513694A (de)
AT (1) ATE193522T1 (de)
AU (1) AU7285296A (de)
CA (1) CA2233075A1 (de)
DE (1) DE69608699T2 (de)
DK (1) DK0862551T3 (de)
ES (1) ES2148800T3 (de)
GB (1) GB9521486D0 (de)
GR (1) GR3034253T3 (de)
PT (1) PT862551E (de)
WO (1) WO1997015550A1 (de)
ZA (1) ZA968795B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618349D0 (en) * 1996-09-03 1996-10-16 Pharmacia Spa N-substituted 2-amino-4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibitory activity
GB9716101D0 (en) * 1997-07-30 1997-10-01 Pharmacia & Upjohn Spa Fused heterocyclic compounds
ES2441874T3 (es) * 2001-06-12 2014-02-06 Wellstat Therapeutics Corporation Compuestos para el tratamiento de trastornos metabólicos
WO2009065906A2 (de) * 2007-11-20 2009-05-28 Cognis Oleochemicals Gmbh Verfahren zur herstellung einer organischen zusammensetzung beinhaltend einen n-nonylether
JP6664814B2 (ja) * 2014-08-18 2020-03-13 国立大学法人大阪大学 新規２−アミノベンゾイル誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE168989T1 (de) * 1991-02-28 1998-08-15 Merrell Pharma Inc Nmda antagonisten
IT1265101B1 (it) * 1993-07-23 1996-10-30 Erba Carlo Spa Derivati dell'acido 2-ammino-4-fenil-4-osso butirrico
US5519055A (en) * 1993-08-06 1996-05-21 University Of Maryland At Baltimore Substituted kynurenines and process for their preparation

Also Published As

Publication number Publication date
DK0862551T3 (da) 2000-10-02
EP0862551B1 (de) 2000-05-31
GB9521486D0 (en) 1995-12-20
ES2148800T3 (es) 2000-10-16
EP0862551A1 (de) 1998-09-09
US5973006A (en) 1999-10-26
JPH11513694A (ja) 1999-11-24
PT862551E (pt) 2000-11-30
WO1997015550A1 (en) 1997-05-01
ZA968795B (en) 1997-05-20
AU7285296A (en) 1997-05-15
GR3034253T3 (en) 2000-12-29
ATE193522T1 (de) 2000-06-15
CA2233075A1 (en) 1997-05-01
DE69608699D1 (de) 2000-07-06

Similar Documents

Publication Publication Date Title
ES2102195T3 (es) Derivados heterociclicos de acido carbonico que se fijan en receptores de retinoides.
DE69919212D1 (de) Aromatische amiden
FI940105A (fi) Menetelmä sertraliinivälituotteiden valmistamiseksi
ATE297203T1 (de) Antithrombotische mitteln
MX9207494A (es) 4(5)-amino-1,8-naftiridinas substituidas, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
NO950297L (no) Prolinamidderivater
DE69420579T2 (de) 9-HYDROXY-PYRIDO [1,2-a] PYRIMIDIN-4-ON-ETHER-DERIVATE
UY24625A1 (es) Derivados de la 4-hidroxi-piperidina
FI952014A (fi) Uusia bisyklisiä merkaptoasetyyliamidilaktaamijohdannaisia, jotka ovat hyödyllisiä enkefalinaasin ja ACE:n inhibiittoreina
DK0705257T3 (da) Aminosyrederivater som NO-syntaseinhibitorer
AU7517400A (en) N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent
DE69231445T2 (de) Triazole enthaltende antifungizide mittel
FI860878A (fi) Aminosyraderivat och foerfarande foer deras framstaellning.
KR950701904A (ko) 치환된(아릴알콕시벤질)아미노프로판아미드 유도체, 이의 제조방법 및 항간질제, 신경보호제 및 항우울증제로서의 이의 용도[Substituted(arylalkoxybenzyl) aminopropanamide derivatives, their preparation and use as anti-epileptic neuroprotective and antidepressant agents]
DE69608699T2 (de) Fluorsubstituierte benzoylpropionsaürederivate
FI940106A (fi) Menetelmä sertraliinin valmistamiseksi
DK0891341T3 (da) 1,3,4-Oxadiazinderivater samt deres anvendelse som pesticider
AU1466295A (en) Amino acid derivatives and their use as phospholipase a2 inhibitors
KR960037677A (ko) 4-인돌릴피페라지닐 유도체
SE8501988L (sv) Iminotiazolidinderivat
UA26459C2 (uk) Іhгібітор впливу амілоїдhих білків
BR9611572A (pt) Produção de um sal de ácido clavulânico
DE69430074D1 (de) Analgetische 4-arylisoindolen
ES2109715T3 (es) Procedimiento para la preparacion de n-carbonilariliminas utiles en la sintesis de taxoides terapeuticamente activos.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee