DE69606364T2 - Prostaglandinderivate - Google Patents
ProstaglandinderivateInfo
- Publication number
- DE69606364T2 DE69606364T2 DE69606364T DE69606364T DE69606364T2 DE 69606364 T2 DE69606364 T2 DE 69606364T2 DE 69606364 T DE69606364 T DE 69606364T DE 69606364 T DE69606364 T DE 69606364T DE 69606364 T2 DE69606364 T2 DE 69606364T2
- Authority
- DE
- Germany
- Prior art keywords
- formula
- blood flow
- prostaglandin derivatives
- prostaglandin
- decubitus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 150000003180 prostaglandins Chemical class 0.000 title 1
- 230000017531 blood circulation Effects 0.000 abstract 2
- GMVPRGQOIOIIMI-UHFFFAOYSA-N (8R,11R,12R,13E,15S)-11,15-Dihydroxy-9-oxo-13-prostenoic acid Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 208000004210 Pressure Ulcer Diseases 0.000 abstract 1
- -1 Prostaglandin E1 ester Chemical class 0.000 abstract 1
- 206010040943 Skin Ulcer Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229960000711 alprostadil Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 238000012423 maintenance Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- 231100000019 skin ulcer Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23898495 | 1995-08-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69606364D1 DE69606364D1 (de) | 2000-03-02 |
| DE69606364T2 true DE69606364T2 (de) | 2000-06-08 |
Family
ID=17038205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69606364T Expired - Fee Related DE69606364T2 (de) | 1995-08-25 | 1996-08-23 | Prostaglandinderivate |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5698590A (de) |
| EP (1) | EP0760366B1 (de) |
| KR (1) | KR100227541B1 (de) |
| AT (1) | ATE189214T1 (de) |
| DE (1) | DE69606364T2 (de) |
| DK (1) | DK0760366T3 (de) |
| ES (1) | ES2142547T3 (de) |
| GR (1) | GR3033195T3 (de) |
| PT (1) | PT760366E (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007074604A1 (ja) * | 2005-12-26 | 2007-07-05 | Ltt Bio-Pharma Co., Ltd. | 水溶性非ペプチド性低分子薬物含有ナノ粒子 |
| WO2008101173A2 (en) * | 2007-02-16 | 2008-08-21 | Cornell University | Biodegradable compositions and materials |
| WO2008139804A1 (ja) * | 2007-05-14 | 2008-11-20 | Ltt Bio-Pharma Co., Ltd. | 徐放性の陰荷電基を持つ低分子薬物含有ナノ粒子 |
| WO2009140430A1 (en) * | 2008-05-14 | 2009-11-19 | Peter Thomas Roth Labs, Llc | Prostaglandin based compositions and method of use thereof |
| US8569279B2 (en) | 2009-05-27 | 2013-10-29 | Sucampo Ag | Method for modulating claudin mediated functions |
| CN102448463A (zh) * | 2009-05-27 | 2012-05-09 | 苏坎波公司 | 用于调节紧密连接蛋白介导的功能和治疗皮肤病的包含前列腺素衍生物的药物组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3632627A (en) * | 1968-01-05 | 1972-01-04 | Smith Kline French Lab | Glyceride derivatives of prostaglandins |
| US4054736A (en) * | 1970-06-10 | 1977-10-18 | Ono Pharmaceutical Co., Ltd. | Clathrate compounds of prostaglandins or their analogues with cyclodextrin |
-
1996
- 1996-08-20 KR KR1019960034329A patent/KR100227541B1/ko not_active IP Right Cessation
- 1996-08-22 US US08/701,486 patent/US5698590A/en not_active Expired - Fee Related
- 1996-08-23 PT PT96306174T patent/PT760366E/pt unknown
- 1996-08-23 DK DK96306174T patent/DK0760366T3/da active
- 1996-08-23 EP EP96306174A patent/EP0760366B1/de not_active Expired - Lifetime
- 1996-08-23 ES ES96306174T patent/ES2142547T3/es not_active Expired - Lifetime
- 1996-08-23 AT AT96306174T patent/ATE189214T1/de not_active IP Right Cessation
- 1996-08-23 DE DE69606364T patent/DE69606364T2/de not_active Expired - Fee Related
-
2000
- 2000-04-12 GR GR20000400889T patent/GR3033195T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0760366B1 (de) | 2000-01-26 |
| KR970010743A (ko) | 1997-03-27 |
| ATE189214T1 (de) | 2000-02-15 |
| DE69606364D1 (de) | 2000-03-02 |
| US5698590A (en) | 1997-12-16 |
| KR100227541B1 (ko) | 1999-11-01 |
| DK0760366T3 (da) | 2000-04-17 |
| PT760366E (pt) | 2000-07-31 |
| EP0760366A1 (de) | 1997-03-05 |
| GR3033195T3 (en) | 2000-08-31 |
| ES2142547T3 (es) | 2000-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |