DE69605531D1 - Carnitinderivat als Arzneimittel zur Behandlung von Arteriosklerose obliterans - Google Patents
Carnitinderivat als Arzneimittel zur Behandlung von Arteriosklerose obliteransInfo
- Publication number
- DE69605531D1 DE69605531D1 DE69605531T DE69605531T DE69605531D1 DE 69605531 D1 DE69605531 D1 DE 69605531D1 DE 69605531 T DE69605531 T DE 69605531T DE 69605531 T DE69605531 T DE 69605531T DE 69605531 D1 DE69605531 D1 DE 69605531D1
- Authority
- DE
- Germany
- Prior art keywords
- treatment
- medicine
- arteriosclerosis obliterans
- carnitine derivative
- carnitine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP96830093A EP0793962B1 (de) | 1996-03-04 | 1996-03-04 | Carnitinderivat als Arzneimittel zur Behandlung von Arteriosklerose obliterans |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69605531D1 true DE69605531D1 (de) | 2000-01-13 |
DE69605531T2 DE69605531T2 (de) | 2000-05-31 |
Family
ID=8225823
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69605531T Expired - Lifetime DE69605531T2 (de) | 1996-03-04 | 1996-03-04 | Carnitinderivat als Arzneimittel zur Behandlung von Arteriosklerose obliterans |
Country Status (13)
Country | Link |
---|---|
US (1) | US5811457A (de) |
EP (1) | EP0793962B1 (de) |
JP (1) | JPH09323927A (de) |
KR (1) | KR100346883B1 (de) |
AT (1) | ATE187329T1 (de) |
CA (1) | CA2198833C (de) |
DE (1) | DE69605531T2 (de) |
DK (1) | DK0793962T3 (de) |
ES (1) | ES2141463T3 (de) |
GR (1) | GR3032903T3 (de) |
PT (1) | PT793962E (de) |
TW (1) | TW349863B (de) |
ZA (1) | ZA971808B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
IT1295408B1 (it) * | 1997-10-03 | 1999-05-12 | Sigma Tau Ind Farmaceuti | Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo |
JP2002529408A (ja) * | 1998-11-11 | 2002-09-10 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | アポトーシスを誘導することができる薬剤の調製のためのプロピオニルl−カルニチンの使用 |
AU1258699A (en) * | 1998-11-11 | 2000-05-29 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of propionylcarnitine for the manufacture of a medicament for inhibiting smooth muscle cell proliferation |
IT1316998B1 (it) * | 2000-03-02 | 2003-05-26 | Sigma Tau Healthscience Spa | Composizione per la prevenzione e/o il trattamento degli effetticitotossici indotti dall'uso di agenti immunosoppressori. |
ITRM20010708A1 (it) * | 2001-12-04 | 2003-06-04 | Sigma Tau Ind Farmaceuti | Uso di una alcanoil l-carnitina per il trattamento della disfunzione erettile. |
US20050159481A1 (en) * | 2002-04-18 | 2005-07-21 | Chugai Seiyaku Kabushiki Kaisha | Medicinal composition for improving angiotension-regulating function of blood vessel endothelium |
US7776913B2 (en) * | 2002-12-13 | 2010-08-17 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Carnitines for treating or preventing disorders caused by andropause |
US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
WO2006061341A1 (en) * | 2004-12-10 | 2006-06-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of propionyl l-carnitine for the preparation of a high-dose medicament for the treatment of peripheral arterial disease |
US7560485B2 (en) * | 2005-10-04 | 2009-07-14 | Sigma-Tau Industrie Parmaceutiche Riunite S.P.A. | Method for treating intermittent claudication comprising the administration of propionyl L-carnitine and a concomitant physical training |
EP2353596A1 (de) | 2010-02-02 | 2011-08-10 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Kombinationszusammensetzung mit L-Carnitin oder Proponyl-L-Carnitin als Wirkstoffe zur Vorbeugung oder Behandlung von chronischer Veneninsuffizienz |
PT2582368T (pt) | 2010-06-16 | 2018-06-04 | Alfasigma Spa | Acetil-carnitina, para utilização num método para o aumento da neurogénese em tecido neuronal |
WO2012069221A1 (en) | 2010-11-22 | 2012-05-31 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutical method for the treatment of the leber optic |
JP2013544857A (ja) | 2010-12-09 | 2013-12-19 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | 皮膚疾患の治療のための局所使用のための組成物 |
EP2783695A1 (de) | 2013-03-28 | 2014-10-01 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Physiologische Ergänzung oder Medikament zur ophthalmischen Verwendung mit L-Carnitin oder Alkanoyl-L-Carnitinen in Kombination mit Eledoisin |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1206954B (it) * | 1979-02-12 | 1989-05-17 | Sigma Tau Ind Farmaceuti | Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche |
IT1142934B (it) * | 1981-11-06 | 1986-10-15 | Sigma Tau Ind Farmaceuti | Uso della carnitina e delle acilcarnitine inferiori nel trattamento terapeutico della patologia delle vene |
US4968719A (en) * | 1989-04-03 | 1990-11-06 | Sigma Tau, Industrie Farmaceutiche Riunite Spa | Method for treating vascular disease |
-
1996
- 1996-03-04 DE DE69605531T patent/DE69605531T2/de not_active Expired - Lifetime
- 1996-03-04 PT PT96830093T patent/PT793962E/pt unknown
- 1996-03-04 DK DK96830093T patent/DK0793962T3/da active
- 1996-03-04 EP EP96830093A patent/EP0793962B1/de not_active Expired - Lifetime
- 1996-03-04 ES ES96830093T patent/ES2141463T3/es not_active Expired - Lifetime
- 1996-03-04 AT AT96830093T patent/ATE187329T1/de active
- 1996-09-16 US US08/714,424 patent/US5811457A/en not_active Expired - Lifetime
-
1997
- 1997-01-28 TW TW086100923A patent/TW349863B/zh not_active IP Right Cessation
- 1997-02-12 KR KR1019970004057A patent/KR100346883B1/ko not_active IP Right Cessation
- 1997-02-28 CA CA002198833A patent/CA2198833C/en not_active Expired - Fee Related
- 1997-03-03 ZA ZA971808A patent/ZA971808B/xx unknown
- 1997-03-04 JP JP9048765A patent/JPH09323927A/ja active Pending
-
2000
- 2000-03-08 GR GR20000400598T patent/GR3032903T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
KR100346883B1 (ko) | 2003-01-06 |
ES2141463T3 (es) | 2000-03-16 |
ZA971808B (en) | 1998-07-31 |
JPH09323927A (ja) | 1997-12-16 |
ATE187329T1 (de) | 1999-12-15 |
CA2198833A1 (en) | 1997-09-04 |
PT793962E (pt) | 2000-05-31 |
CA2198833C (en) | 2003-07-22 |
DE69605531T2 (de) | 2000-05-31 |
US5811457A (en) | 1998-09-22 |
MX9701294A (es) | 1997-09-30 |
TW349863B (en) | 1999-01-11 |
DK0793962T3 (da) | 2000-05-22 |
EP0793962B1 (de) | 1999-12-08 |
GR3032903T3 (en) | 2000-07-31 |
EP0793962A1 (de) | 1997-09-10 |
KR970064602A (ko) | 1997-10-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |