ES2141463T3 - Medicamento conteniendo un derivado de la carnitina para el tratamiento de la arteriosclerosis obliterans. - Google Patents

Medicamento conteniendo un derivado de la carnitina para el tratamiento de la arteriosclerosis obliterans.

Info

Publication number
ES2141463T3
ES2141463T3 ES96830093T ES96830093T ES2141463T3 ES 2141463 T3 ES2141463 T3 ES 2141463T3 ES 96830093 T ES96830093 T ES 96830093T ES 96830093 T ES96830093 T ES 96830093T ES 2141463 T3 ES2141463 T3 ES 2141463T3
Authority
ES
Spain
Prior art keywords
carnitine
treatment
derivative
arteriosclerosis obliterans
medication containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96830093T
Other languages
English (en)
Inventor
Marco Corsi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of ES2141463T3 publication Critical patent/ES2141463T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

SE MUESTRA EL USO DE UN PROPIONIL L-CARNITINA Y SALES ACEPTABLES FARMACOLOGICAMENTE DE LA MISMA PARA ELABORAR UN MEDICAMENTO PARA TRATAR LAS REMISIONES DE LA ARTERIOESCLEROSIS CRONICA QUE ESTA INDICADO SELECTIVAMENTE PARA EL TRATAMIENTO DE PACIENTES CON REMISION INTERMITENTE INCAPACITANTE SEVERA.
ES96830093T 1996-03-04 1996-03-04 Medicamento conteniendo un derivado de la carnitina para el tratamiento de la arteriosclerosis obliterans. Expired - Lifetime ES2141463T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96830093A EP0793962B1 (en) 1996-03-04 1996-03-04 Medicament containing a carnitine derivative for treating arteriosclerosis obliterans

Publications (1)

Publication Number Publication Date
ES2141463T3 true ES2141463T3 (es) 2000-03-16

Family

ID=8225823

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96830093T Expired - Lifetime ES2141463T3 (es) 1996-03-04 1996-03-04 Medicamento conteniendo un derivado de la carnitina para el tratamiento de la arteriosclerosis obliterans.

Country Status (13)

Country Link
US (1) US5811457A (es)
EP (1) EP0793962B1 (es)
JP (1) JPH09323927A (es)
KR (1) KR100346883B1 (es)
AT (1) ATE187329T1 (es)
CA (1) CA2198833C (es)
DE (1) DE69605531T2 (es)
DK (1) DK0793962T3 (es)
ES (1) ES2141463T3 (es)
GR (1) GR3032903T3 (es)
PT (1) PT793962E (es)
TW (1) TW349863B (es)
ZA (1) ZA971808B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276253B1 (it) 1995-12-15 1997-10-27 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi
IT1295408B1 (it) * 1997-10-03 1999-05-12 Sigma Tau Ind Farmaceuti Associazione di l-carnitina e alcanoil l-carnitine per il trattamento dell'alcoolismo
EP1128823A1 (en) * 1998-11-11 2001-09-05 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Use of propionyl l-carnitine for the preparation of a medicament capable of inducing apoptosis
AU1258699A (en) * 1998-11-11 2000-05-29 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of propionylcarnitine for the manufacture of a medicament for inhibiting smooth muscle cell proliferation
IT1316998B1 (it) * 2000-03-02 2003-05-26 Sigma Tau Healthscience Spa Composizione per la prevenzione e/o il trattamento degli effetticitotossici indotti dall'uso di agenti immunosoppressori.
ITRM20010708A1 (it) 2001-12-04 2003-06-04 Sigma Tau Ind Farmaceuti Uso di una alcanoil l-carnitina per il trattamento della disfunzione erettile.
KR20040101521A (ko) * 2002-04-18 2004-12-02 추가이 세이야쿠 가부시키가이샤 혈관 내피의 혈관 장력 조절 기능을 개선하기 위한 의약조성물
US7776913B2 (en) * 2002-12-13 2010-08-17 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Carnitines for treating or preventing disorders caused by andropause
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
WO2006061341A1 (en) * 2004-12-10 2006-06-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Use of propionyl l-carnitine for the preparation of a high-dose medicament for the treatment of peripheral arterial disease
US7560485B2 (en) * 2005-10-04 2009-07-14 Sigma-Tau Industrie Parmaceutiche Riunite S.P.A. Method for treating intermittent claudication comprising the administration of propionyl L-carnitine and a concomitant physical training
EP2353596A1 (en) 2010-02-02 2011-08-10 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Combination composition, comprising as active ingredients L-carnitine or propionyl L-carnitine, for the prevention or treatment of chronic venous insufficiency
SG10201503032UA (en) 2010-06-16 2015-06-29 Sigma Tau Ind Farmaceuti Acetyl-carnitine for use in a method for increasing neurogenesis in neural tissue
US9114120B2 (en) 2010-11-22 2015-08-25 Sigma-Tau Industrie Farmaceutiche Riunite, S.P.A. Therapeutical method for the treatment of the Leber optic neuropathy
KR20130140100A (ko) 2010-12-09 2013-12-23 씨그마-토 인더스트리에 파마슈티체 리유니테 에스. 피. 에이. 피부 장애 치료용 국소 사용을 위한 조성물
EP2783695A1 (en) 2013-03-28 2014-10-01 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Physiological supplement or medicament for ophthalmic use containing L-carnitine or alkanoyl L-carnitines in combination with eledoisin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1206954B (it) * 1979-02-12 1989-05-17 Sigma Tau Ind Farmaceuti Agenti terapeutici a base di un acil derivato della carnitina per la cura di vasculopatie periferiche
IT1142934B (it) * 1981-11-06 1986-10-15 Sigma Tau Ind Farmaceuti Uso della carnitina e delle acilcarnitine inferiori nel trattamento terapeutico della patologia delle vene
US4968719A (en) * 1989-04-03 1990-11-06 Sigma Tau, Industrie Farmaceutiche Riunite Spa Method for treating vascular disease

Also Published As

Publication number Publication date
GR3032903T3 (en) 2000-07-31
DK0793962T3 (da) 2000-05-22
EP0793962B1 (en) 1999-12-08
EP0793962A1 (en) 1997-09-10
ZA971808B (en) 1998-07-31
MX9701294A (es) 1997-09-30
JPH09323927A (ja) 1997-12-16
TW349863B (en) 1999-01-11
ATE187329T1 (de) 1999-12-15
DE69605531T2 (de) 2000-05-31
US5811457A (en) 1998-09-22
KR100346883B1 (ko) 2003-01-06
DE69605531D1 (de) 2000-01-13
CA2198833A1 (en) 1997-09-04
CA2198833C (en) 2003-07-22
PT793962E (pt) 2000-05-31
KR970064602A (ko) 1997-10-13

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