DE69600407T2 - Stabilisierende lösungen für troponin - Google Patents

Stabilisierende lösungen für troponin

Info

Publication number
DE69600407T2
DE69600407T2 DE69600407T DE69600407T DE69600407T2 DE 69600407 T2 DE69600407 T2 DE 69600407T2 DE 69600407 T DE69600407 T DE 69600407T DE 69600407 T DE69600407 T DE 69600407T DE 69600407 T2 DE69600407 T2 DE 69600407T2
Authority
DE
Germany
Prior art keywords
troponin
stabilizing solutions
stabilizing
solutions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69600407T
Other languages
English (en)
Other versions
DE69600407D1 (de
Inventor
Cathy Flaa
Alberto Sabucedo
Bruce Chin
Roger Bauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Dade Behring Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Inc filed Critical Dade Behring Inc
Publication of DE69600407D1 publication Critical patent/DE69600407D1/de
Application granted granted Critical
Publication of DE69600407T2 publication Critical patent/DE69600407T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4712—Muscle proteins, e.g. myosin, actin, protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69600407T 1995-03-07 1996-03-06 Stabilisierende lösungen für troponin Expired - Lifetime DE69600407T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/400,158 US6165981A (en) 1995-03-07 1995-03-07 Stabilizing solutions for proteins and peptides
PCT/US1996/003034 WO1996027661A1 (en) 1995-03-07 1996-03-06 Stabilizing solutions for proteins and peptides

Publications (2)

Publication Number Publication Date
DE69600407D1 DE69600407D1 (de) 1998-08-13
DE69600407T2 true DE69600407T2 (de) 1999-04-29

Family

ID=23582452

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69600407T Expired - Lifetime DE69600407T2 (de) 1995-03-07 1996-03-06 Stabilisierende lösungen für troponin

Country Status (8)

Country Link
US (1) US6165981A (de)
EP (1) EP0759074B1 (de)
JP (1) JP3740644B2 (de)
AU (1) AU698790B2 (de)
CA (1) CA2189737A1 (de)
DE (1) DE69600407T2 (de)
ES (1) ES2121479T3 (de)
WO (1) WO1996027661A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627404B1 (en) * 1995-04-18 2003-09-30 Biosite, Inc. Methods for improving the recovery of troponin I and T in membranes, filters and vessels
US7006874B2 (en) * 1996-01-05 2006-02-28 Thermage, Inc. Treatment apparatus with electromagnetic energy delivery device and non-volatile memory
AU4160597A (en) * 1996-08-23 1998-03-06 Eli Lilly And Company Protein formulations
DE69713517D1 (de) * 1996-10-15 2002-07-25 Medical Analysis Systems Inc Verfahren zur Stabilisierung von Troponin I (CTnI) durch Konjugation mit einem activen Polymer
FR2756827B1 (fr) * 1996-12-05 1999-01-29 Pasteur Sanofi Diagnostics Composes synthetiques biepitopiques utilisables comme etalons dans les dosages biologiques de la troponine i
US6156521A (en) * 1997-12-19 2000-12-05 Biosite Diagnostics, Inc. Methods for the recovery and measurement of troponin complexes
EP0983091A4 (de) * 1997-01-17 2002-04-10 Lilly Co Eli Formulierungen auf der basis des proteins für fettleibigkeit
KR20000070338A (ko) * 1997-01-20 2000-11-25 나가시마 카쭈시게, 노미야마 아키히코 펩티드의 안정화 방법 및 당해 방법을 이용한 펩티드 함유 동결건조 의약조성물
AU6569998A (en) * 1997-03-20 1998-10-12 Eli Lilly And Company Obesity protein formulations
US6248869B1 (en) 1997-05-29 2001-06-19 Medical Analysis Systems, Inc. Troponin I forms and use of the same
WO1998056900A1 (en) * 1997-06-13 1998-12-17 Medical Analysis Systems Inc. (Mas) Stabilized compositions of cardiac markers
WO2000023585A1 (en) 1998-10-21 2000-04-27 Spectral Diagnostics, Inc. Cardiac troponin i polypeptide fragments and uses in diagnostics
DE19930676B4 (de) 1999-07-02 2006-01-19 Sanofi-Aventis Deutschland Gmbh Verfahren zur Stabilisierung von Insulin, Insulinderivaten und/oder deren Vorläufer in komplexen Mischungen bei deren Lagerung in wäßrigen Lösungsmitteln
FR2797689B1 (fr) 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics Utilisation de composes synthetiques pour des immunodosages
US7078486B2 (en) 1999-12-10 2006-07-18 Spectral Diagnostics, Inc. Single-chain polypeptides comprising troponin I and troponin C
WO2002017956A2 (en) * 2000-08-31 2002-03-07 Chiron Corporation Stabilized fgf formulations containing reducing agents
US6962700B1 (en) * 2000-09-13 2005-11-08 Atopix Pharmaceuticals Corporation Method of manufacturing immune globulin
US6538104B2 (en) 2001-04-27 2003-03-25 Medical Analysis Systems, Inc. Stabilization of cardiac troponin I subunits and complexes
US6927062B2 (en) * 2002-11-25 2005-08-09 Agdia, Inc. Controls and standards for assays and method for manufacture thereof
US7291501B2 (en) * 2003-07-16 2007-11-06 Abbott Laboratories Stable compositions for measuring human natriuretic peptides
US7445933B2 (en) * 2003-07-16 2008-11-04 Abbott Laboratories, Inc. Stable calibrators or controls for measuring human natriuretic peptides
US20050136542A1 (en) * 2003-12-19 2005-06-23 Beckman Coulter, Inc. Stabilized liquid reference solutions
DE602006013443D1 (de) * 2005-04-28 2010-05-20 Abbott Lab Stabilisierung von herz-troponin
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
US7678764B2 (en) * 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
JP5323832B2 (ja) * 2007-08-07 2013-10-23 アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー 酸性水溶液中にｇｄｆ−５を含むタンパク質製剤
CA2720845A1 (en) 2008-04-14 2009-10-22 Advanced Technologies And Regenerative Medicine, Llc Liquid buffered gdf-5 formulations
US20110306148A1 (en) 2010-06-14 2011-12-15 Siemens Healthcare Diagnostics Inc. Composition for use as an assay reagent
CN107167613B (zh) * 2017-06-22 2018-10-02 深圳清华大学研究院 用于等离子体金芯片的蛋白点样缓冲液
CN109254153B (zh) * 2018-08-27 2021-10-12 广东菲鹏生物有限公司 肌红蛋白的抗氧化剂及其应用
US20210212311A1 (en) * 2018-09-28 2021-07-15 Siemens Healthcare Diagnostics Inc. Storage solution compositions for the stabilization of purified müllerian inhibiting substance (mis) and methods of use and production related thereto
CN109725148B (zh) * 2018-12-30 2022-05-03 广东环凯微生物科技有限公司 一种免疫磁珠保存液
AU2021260878A1 (en) 2020-04-20 2022-11-17 Vestaron Corporation Proteolytically stable U1-agatoxin-Ta1b variant polypeptides for pest control
AU2021265277A1 (en) 2020-05-01 2022-12-08 Vestaron Corporation Insecticidal combinations
CN114324882B (zh) * 2020-10-12 2022-12-27 广东菲鹏生物有限公司 蛋白稳定剂及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US5217890A (en) * 1991-08-20 1993-06-08 Eastman Kodak Company Stabilized composition containing creatine kinase and protein having blocked sulfhydryl groups
FR2701954B1 (fr) * 1993-02-23 1995-07-07 Pasteur Sanofi Diagnostics Composition stabilisée de troponine pour immunoessais et procédé de stabilisation de troponine pour immunoessais.
JPH09503050A (ja) * 1993-05-17 1997-03-25 フォートロン バイオサイエンス インク． 心臓トロポニン▲ｉ▼のアッセイ

Also Published As

Publication number Publication date
DE69600407D1 (de) 1998-08-13
AU698790B2 (en) 1998-11-05
CA2189737A1 (en) 1996-09-12
AU5092996A (en) 1996-09-23
EP0759074A1 (de) 1997-02-26
EP0759074B1 (de) 1998-07-08
US6165981A (en) 2000-12-26
ES2121479T3 (es) 1998-11-16
JPH10500704A (ja) 1998-01-20
WO1996027661A1 (en) 1996-09-12
JP3740644B2 (ja) 2006-02-01

Similar Documents

Publication Publication Date Title
DE69600407T2 (de) Stabilisierende lösungen für troponin
DE69601802T2 (de) Trägerband für bauteile
DE69603416T2 (de) Elektrochemischer Immunobiosensor
DE69623245D1 (de) Elektrochemisches Abscheideverfahren
DE9413768U1 (de) Kleinkoffer
DE69620379T2 (de) Gummiervorrichtung
DE69605517D1 (de) Trägerbalken für Anhänger
DE29500497U1 (de) Kleinkoffer
DE69534393D1 (de) Melanininhibitoren enthaltende Salbe
FI961467A0 (fi) Sähkökemiallinen menetelmä
DE69617842D1 (de) Gummiervorrichtung
DE29504014U1 (de) Stabilisierungselement für Abstandhalter
DE29514643U1 (de) Zusatzbox für Diabetiker-Box
DE29500348U1 (de) Kleinkoffer
DE29513220U1 (de) Doppelscheibenwischer
FI952508A0 (fi) Kalenteri
KR970032410U (ko) 범용화한 승합차
DE29502072U1 (de) Mehrfachpendel
DE29520800U1 (de) Winkelmesser
DE29509888U1 (de) Abstützung für Hebezeuge
SE9401953L (sv) Tätningsring
DE29512025U1 (de) Stütze für Stehleiter
DE29506939U1 (de) Saitenhalter
KR970035077U (ko) 자동차용 흙 튀김 방지 구조
KR970038137U (ko) 자동차용 흙 튀김 방지 구조

Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication of lapse of patent is to be deleted
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC., DEERFIELD, US

8328 Change in the person/name/address of the agent

Representative=s name: PLATE SCHWEITZER ZOUNEK PATENTANWAELTE, 65203 WIES