DE69532416D1 - Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie - Google Patents
Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrieInfo
- Publication number
- DE69532416D1 DE69532416D1 DE69532416T DE69532416T DE69532416D1 DE 69532416 D1 DE69532416 D1 DE 69532416D1 DE 69532416 T DE69532416 T DE 69532416T DE 69532416 T DE69532416 T DE 69532416T DE 69532416 D1 DE69532416 D1 DE 69532416D1
- Authority
- DE
- Germany
- Prior art keywords
- flow cytometry
- high rate
- rate drop
- drop production
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000684 flow cytometry Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N15/1409—Handling samples, e.g. injecting samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1406—Control of droplet point
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
- Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32327094A | 1994-10-14 | 1994-10-14 | |
US323270 | 1994-10-14 | ||
PCT/US1995/013308 WO1996012171A2 (en) | 1994-10-14 | 1995-10-13 | High speed flow cytometer droplet formation system |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69532416D1 true DE69532416D1 (de) | 2004-02-12 |
DE69532416T2 DE69532416T2 (de) | 2004-12-02 |
Family
ID=23258439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69532416T Expired - Lifetime DE69532416T2 (de) | 1994-10-14 | 1995-10-13 | Methode und vorrichtung zur tröpfchenerzeugung mit hoher rate bei der durchfluss-cytometrie |
Country Status (6)
Country | Link |
---|---|
US (1) | US6133044A (de) |
EP (1) | EP0786078B1 (de) |
JP (1) | JPH10507524A (de) |
AU (1) | AU698929B2 (de) |
DE (1) | DE69532416T2 (de) |
WO (1) | WO1996012171A2 (de) |
Families Citing this family (60)
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US6861265B1 (en) | 1994-10-14 | 2005-03-01 | University Of Washington | Flow cytometer droplet formation system |
DE69830598T2 (de) | 1997-01-31 | 2006-05-18 | The Horticulture And Food Research Institute Of New Zealand Limited | Optische vorrichtung und methode |
US6071689A (en) * | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
GB2381004B (en) * | 1997-12-31 | 2003-06-04 | Xy Inc | A method of sorting cells |
US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
CN100357723C (zh) | 1998-02-20 | 2007-12-26 | Xy公司 | 用于分类流量细胞计数器的振动系统和流量细胞计数方法 |
US6746873B1 (en) * | 1998-02-20 | 2004-06-08 | Xy, Inc. | Vibratory system for a sorting flow cytometer |
US6248590B1 (en) * | 1998-02-27 | 2001-06-19 | Cytomation, Inc. | Method and apparatus for flow cytometry |
BR9912539A (pt) | 1998-07-30 | 2001-05-02 | Xy Inc | Sistema equino para inseminação artificial não-cirúrgica |
US6372506B1 (en) * | 1999-07-02 | 2002-04-16 | Becton, Dickinson And Company | Apparatus and method for verifying drop delay in a flow cytometer |
EP1099484B1 (de) * | 1999-11-11 | 2006-06-07 | The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin | Vorrichtung und Verfahren zur Verabreichung von Tropfen |
US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
US6263745B1 (en) | 1999-12-03 | 2001-07-24 | Xy, Inc. | Flow cytometer nozzle and flow cytometer sample handling methods |
EP2258172B1 (de) | 2000-05-09 | 2017-04-19 | Xy, Llc | Durchflusszytometer zum Differenzieren von X-Chromosom-Lager und Y-Chromosom-Lagerpopulationen von Spermatozoiden |
US20020086431A1 (en) * | 2000-08-21 | 2002-07-04 | Markham Walter Bruce | Sample preparation and slide plating apparatus and method |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
BRPI0115791B1 (pt) | 2000-11-29 | 2020-05-05 | Colorado State Univ | sistema para fertilização in vitro com espematozóides separados em populações portadoras de cromossoma x e cromossoma y |
US20020106308A1 (en) * | 2001-02-02 | 2002-08-08 | Zweifel Ronald A. | Microdrop dispensing apparatus |
US6669909B2 (en) * | 2001-03-26 | 2003-12-30 | Allegro Technologies Limited | Liquid droplet dispensing |
US7345758B2 (en) * | 2001-05-17 | 2008-03-18 | Cytopeia | Apparatus for analyzing and sorting biological particles |
US20030211009A1 (en) * | 2001-05-18 | 2003-11-13 | Buchanan Kris S. | Rapid multi-material sample input system |
US6808683B2 (en) | 2001-09-25 | 2004-10-26 | Cytonome, Inc. | Droplet dispensing system |
US6976590B2 (en) | 2002-06-24 | 2005-12-20 | Cytonome, Inc. | Method and apparatus for sorting particles |
US9943847B2 (en) | 2002-04-17 | 2018-04-17 | Cytonome/St, Llc | Microfluidic system including a bubble valve for regulating fluid flow through a microchannel |
US7362424B2 (en) * | 2002-04-24 | 2008-04-22 | The Institute For Systems Biology | Compositions and methods for drop boundary detection and radiation beam alignment |
EP1545203B1 (de) | 2002-08-01 | 2016-10-19 | Xy, Llc | Mit niederdruck arbeitendes spermazellentrennsystem |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
WO2004017041A2 (en) | 2002-08-15 | 2004-02-26 | Xy, Inc. | High resolution flow cytometer |
JP3898103B2 (ja) * | 2002-08-26 | 2007-03-28 | 独立行政法人科学技術振興機構 | 細胞分析分離装置 |
US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
US7201875B2 (en) * | 2002-09-27 | 2007-04-10 | Becton Dickinson And Company | Fixed mounted sorting cuvette with user replaceable nozzle |
JP3891925B2 (ja) * | 2002-12-03 | 2007-03-14 | ベイバイオサイエンス株式会社 | 生物学的粒子の情報を得る装置 |
EP2305172B1 (de) | 2003-03-28 | 2016-05-11 | Inguran, LLC | Vorrichtung und Verfahren zur Bereitstellung von geschlechtssortierten Tierspermien |
CA2566749C (en) | 2003-05-15 | 2017-02-21 | Xy, Inc. | Efficient haploid cell sorting for flow cytometer systems |
US20050147976A1 (en) * | 2003-12-29 | 2005-07-07 | Xing Su | Methods for determining nucleotide sequence information |
EP2151243B1 (de) | 2004-03-29 | 2012-10-24 | Inguran, LLC | Spermasuspensionen zur Sortierung in X- oder Y-Chromosomen-tragende angereicherte Populationen |
JP4304120B2 (ja) * | 2004-04-30 | 2009-07-29 | ベイバイオサイエンス株式会社 | 生物学的粒子をソーティングする装置及び方法 |
WO2006012597A2 (en) | 2004-07-22 | 2006-02-02 | Monsanto Technology Llc | Process for enriching a population of sperm cells |
ES2264608B2 (es) * | 2004-09-30 | 2007-08-16 | Universidad De Sevilla | Dispositivo y procedimiento para la atomizacion neumatica de liquidos mediante flujo implosivo de gas. |
US20070116608A1 (en) * | 2005-11-23 | 2007-05-24 | Birdsell Michael P | Vented ceramic tip arrangement for use with a microarray |
US20070269348A1 (en) * | 2006-05-19 | 2007-11-22 | Cytopeia Incorporated | Enhanced droplet flow cytometer system and method |
ITTO20100651A1 (it) | 2010-07-28 | 2012-01-29 | Ist Sperimentale It Lazzaro Spallanza | Procedimento ed apparecchiatura per la caratterizzazione e la separazione di spermatozoi con sensori micrometrici a leva sospesa |
WO2013192495A2 (en) * | 2012-06-22 | 2013-12-27 | Bio-Rad Laboratories, Inc. | Condensed geometry nozzle for flow cytometry |
US11668640B2 (en) | 2015-03-06 | 2023-06-06 | Inguran, Llc | Nozzle assembly for a flow cytometry system and methods of manufacture |
AU2013318001B2 (en) | 2012-09-19 | 2016-06-16 | Inguran, Llc | Flow cytometer nozzle tip |
CA2885170C (en) | 2012-09-19 | 2019-02-19 | Inguran, Llc | Nozzle assembly for a flow cytometer system and methods of manufacture |
WO2014169231A1 (en) | 2013-04-12 | 2014-10-16 | Norton Pierce O | Automated set-up for cell sorting |
WO2015111293A1 (ja) * | 2014-01-24 | 2015-07-30 | ソニー株式会社 | 粒子分取装置及び粒子分取方法 |
US11577366B2 (en) | 2016-12-12 | 2023-02-14 | Omax Corporation | Recirculation of wet abrasive material in abrasive waterjet systems and related technology |
USD869676S1 (en) | 2017-03-28 | 2019-12-10 | Becton, Dickinson And Company | Particle sorting module |
USD868991S1 (en) | 2017-03-28 | 2019-12-03 | Becton, Dickinson And Company | Register block |
US10443838B2 (en) * | 2017-04-05 | 2019-10-15 | Hall Labs Llc | Method for forming consistently-sized and controllably-timed droplets |
USD864415S1 (en) | 2018-01-30 | 2019-10-22 | Becton, Dickinson And Company | Particle sorting system |
USD882817S1 (en) | 2018-01-30 | 2020-04-28 | Becton, Dickinson And Company | Sample container |
USD872296S1 (en) | 2018-01-30 | 2020-01-07 | Becton, Dickinson And Company | Particle sorting module |
USD876668S1 (en) | 2018-01-30 | 2020-02-25 | Becton, Dickinson And Company | Particle sorting module mount |
JP7073805B2 (ja) * | 2018-03-14 | 2022-05-24 | 株式会社リコー | 液滴形成ヘッド、液滴形成装置、及び液滴形成方法 |
US20230236173A1 (en) | 2020-06-22 | 2023-07-27 | Westfaelische Wilhelms-Universitaet Muenster | Sperm stratification |
JPWO2022024477A1 (de) * | 2020-07-28 | 2022-02-03 | ||
JPWO2022024575A1 (de) * | 2020-07-28 | 2022-02-03 |
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-
1995
- 1995-10-13 JP JP8513421A patent/JPH10507524A/ja active Pending
- 1995-10-13 AU AU39582/95A patent/AU698929B2/en not_active Expired
- 1995-10-13 EP EP95937480A patent/EP0786078B1/de not_active Expired - Lifetime
- 1995-10-13 WO PCT/US1995/013308 patent/WO1996012171A2/en active IP Right Grant
- 1995-10-13 DE DE69532416T patent/DE69532416T2/de not_active Expired - Lifetime
-
1996
- 1996-04-16 US US08/627,963 patent/US6133044A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU698929B2 (en) | 1998-11-12 |
DE69532416T2 (de) | 2004-12-02 |
EP0786078B1 (de) | 2004-01-07 |
JPH10507524A (ja) | 1998-07-21 |
EP0786078A2 (de) | 1997-07-30 |
US6133044A (en) | 2000-10-17 |
WO1996012171A3 (en) | 1996-08-01 |
WO1996012171A2 (en) | 1996-04-25 |
AU3958295A (en) | 1996-05-06 |
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