DE69529050D1 - Orale dosierungsformen mit pulverschicht - Google Patents

Orale dosierungsformen mit pulverschicht

Info

Publication number
DE69529050D1
DE69529050D1 DE69529050T DE69529050T DE69529050D1 DE 69529050 D1 DE69529050 D1 DE 69529050D1 DE 69529050 T DE69529050 T DE 69529050T DE 69529050 T DE69529050 T DE 69529050T DE 69529050 D1 DE69529050 D1 DE 69529050D1
Authority
DE
Germany
Prior art keywords
oral dosage
dosage forms
powder layer
powder
morphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69529050T
Other languages
English (en)
Other versions
DE69529050T2 (de
Inventor
Benjamin Oshlack
Pedi, Jr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of DE69529050D1 publication Critical patent/DE69529050D1/de
Publication of DE69529050T2 publication Critical patent/DE69529050T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
DE69529050T 1994-05-25 1995-05-01 Orale dosierungsformen mit pulverschicht Expired - Lifetime DE69529050T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/249,150 US5411745A (en) 1994-05-25 1994-05-25 Powder-layered morphine sulfate formulations
PCT/US1995/005680 WO1995031972A1 (en) 1994-05-25 1995-05-01 Powder-layered oral dosage forms

Publications (2)

Publication Number Publication Date
DE69529050D1 true DE69529050D1 (de) 2003-01-16
DE69529050T2 DE69529050T2 (de) 2003-10-09

Family

ID=22942251

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69529050T Expired - Lifetime DE69529050T2 (de) 1994-05-25 1995-05-01 Orale dosierungsformen mit pulverschicht

Country Status (7)

Country Link
US (1) US5411745A (de)
EP (1) EP0711152B1 (de)
JP (1) JP3015105B2 (de)
AT (1) ATE228825T1 (de)
AU (1) AU2436395A (de)
DE (1) DE69529050T2 (de)
WO (1) WO1995031972A1 (de)

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Also Published As

Publication number Publication date
US5411745A (en) 1995-05-02
EP0711152B1 (de) 2002-12-04
AU2436395A (en) 1995-12-18
ATE228825T1 (de) 2002-12-15
JP3015105B2 (ja) 2000-03-06
WO1995031972A1 (en) 1995-11-30
DE69529050T2 (de) 2003-10-09
EP0711152A4 (de) 1997-09-17
EP0711152A1 (de) 1996-05-15
JPH09500914A (ja) 1997-01-28

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