DE69524100D1 - Verfahren zur herstellung von aminoazobicycloalkanen aus oximen - Google Patents

Verfahren zur herstellung von aminoazobicycloalkanen aus oximen

Info

Publication number
DE69524100D1
DE69524100D1 DE69524100T DE69524100T DE69524100D1 DE 69524100 D1 DE69524100 D1 DE 69524100D1 DE 69524100 T DE69524100 T DE 69524100T DE 69524100 T DE69524100 T DE 69524100T DE 69524100 D1 DE69524100 D1 DE 69524100D1
Authority
DE
Germany
Prior art keywords
aminoazobicycloalcanes
oximes
producing
producing aminoazobicycloalcanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69524100T
Other languages
English (en)
Other versions
DE69524100T2 (de
Inventor
E Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE69524100D1 publication Critical patent/DE69524100D1/de
Application granted granted Critical
Publication of DE69524100T2 publication Critical patent/DE69524100T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Indole Compounds (AREA)
DE69524100T 1994-07-23 1995-07-18 Verfahren zur herstellung von aminoazobicycloalkanen aus oximen Expired - Lifetime DE69524100T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9414900A GB9414900D0 (en) 1994-07-23 1994-07-23 Novel process
PCT/EP1995/002824 WO1996003401A2 (en) 1994-07-23 1995-07-18 Process for the production of aminoazobicycloalkanes from oximes

Publications (2)

Publication Number Publication Date
DE69524100D1 true DE69524100D1 (de) 2002-01-03
DE69524100T2 DE69524100T2 (de) 2002-08-22

Family

ID=10758800

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524100T Expired - Lifetime DE69524100T2 (de) 1994-07-23 1995-07-18 Verfahren zur herstellung von aminoazobicycloalkanen aus oximen

Country Status (9)

Country Link
US (1) US5856489A (de)
EP (1) EP0772613B1 (de)
JP (1) JP4001380B2 (de)
DE (1) DE69524100T2 (de)
ES (1) ES2167447T3 (de)
GB (1) GB9414900D0 (de)
HK (1) HK1012349A1 (de)
MX (1) MX9700596A (de)
WO (1) WO1996003401A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1313660B1 (it) * 1999-10-01 2002-09-09 Dompe Spa Procedimento stereoselettivo per la preparazione di endo-3-amminoazabicicloalcani.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
NZ197356A (en) * 1980-06-18 1984-05-31 Beecham Group Ltd Ar-alkylsulphinyl-n-(azaicycloalkyl(alkyl)) benzamides
US4432983A (en) * 1981-04-30 1984-02-21 Research Corporation Conformationally restricted histamine H2 -receptor antagonists containing a tropane ring
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
US5258528A (en) * 1990-11-30 1993-11-02 Warner-Lambert Company Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group

Also Published As

Publication number Publication date
EP0772613B1 (de) 2001-11-21
HK1012349A1 (en) 1999-07-30
MX9700596A (es) 1997-06-28
JPH10503188A (ja) 1998-03-24
JP4001380B2 (ja) 2007-10-31
WO1996003401A2 (en) 1996-02-08
EP0772613A2 (de) 1997-05-14
WO1996003401A3 (en) 1996-07-04
ES2167447T3 (es) 2002-05-16
DE69524100T2 (de) 2002-08-22
GB9414900D0 (en) 1994-09-14
US5856489A (en) 1999-01-05

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DE69524100D1 (de) Verfahren zur herstellung von aminoazobicycloalkanen aus oximen

Legal Events

Date Code Title Description
8364 No opposition during term of opposition