DE69518410T2 - 22-thiavitamin-d3-derivate - Google Patents
22-thiavitamin-d3-derivateInfo
- Publication number
- DE69518410T2 DE69518410T2 DE69518410T DE69518410T DE69518410T2 DE 69518410 T2 DE69518410 T2 DE 69518410T2 DE 69518410 T DE69518410 T DE 69518410T DE 69518410 T DE69518410 T DE 69518410T DE 69518410 T2 DE69518410 T2 DE 69518410T2
- Authority
- DE
- Germany
- Prior art keywords
- hydroxy
- represents hydrogen
- thiavitamin
- derivatives
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000003966 growth inhibitor Substances 0.000 abstract 1
- 210000002510 keratinocyte Anatomy 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- 150000003710 vitamin D derivatives Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10736694 | 1994-04-11 | ||
| PCT/JP1995/000699 WO1995027697A1 (fr) | 1994-04-11 | 1995-04-10 | Derive de la 22-thiavitamine d¿3? |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69518410D1 DE69518410D1 (de) | 2000-09-21 |
| DE69518410T2 true DE69518410T2 (de) | 2000-12-14 |
Family
ID=14457272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69518410T Expired - Lifetime DE69518410T2 (de) | 1994-04-11 | 1995-04-10 | 22-thiavitamin-d3-derivate |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5824811A (de) |
| EP (1) | EP0755922B1 (de) |
| KR (1) | KR100244060B1 (de) |
| CN (1) | CN1046502C (de) |
| AT (1) | ATE195513T1 (de) |
| AU (1) | AU2148295A (de) |
| BR (1) | BR9507355A (de) |
| DE (1) | DE69518410T2 (de) |
| DK (1) | DK0755922T3 (de) |
| ES (1) | ES2150560T3 (de) |
| GR (1) | GR3034322T3 (de) |
| PT (1) | PT755922E (de) |
| RU (1) | RU2142941C1 (de) |
| WO (1) | WO1995027697A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9226877D0 (en) * | 1992-12-23 | 1993-02-17 | Leo Pharm Prod Ltd | Chemical compounds |
| US6869940B2 (en) | 1995-12-28 | 2005-03-22 | Chugai Seiyaku Kabushiki Kaisha | Malignant tumor metastasis inhibitors |
| AU1152997A (en) | 1995-12-28 | 1997-07-28 | Chugai Seiyaku Kabushiki Kaisha | Malignant tumor metastasis inhibitors |
| US6184398B1 (en) * | 1996-12-20 | 2001-02-06 | Chugai Seiyaku Kabushiki Kaisha | 16-ene-vitamin D derivatives |
| KR100573234B1 (ko) * | 1996-12-20 | 2006-04-24 | 쥬가이 세이야쿠 가부시키가이샤 | 16-엔-비타민 ｄ 유도체 |
| WO1998051678A1 (en) | 1997-05-16 | 1998-11-19 | Women & Infants Hospital | CYCLIC ETHER VITAMIN D3 COMPOUNDS, 1α (OH) 3-EPI-VITAMIN D3 COMPOUNDS AND USES THEREOF |
| WO2001016099A1 (fr) * | 1999-08-27 | 2001-03-08 | Chugai Seiyaku Kabushiki Kaisha | DÉRIVÉS DE VITAMINE D AYANT DES SUBSTITUANTS À LA POSITION 2$g(a) |
| GB2364231A (en) * | 2000-04-05 | 2002-01-23 | Bush Boake Allen Ltd | Flavouring agent |
| US6899911B2 (en) * | 2000-04-05 | 2005-05-31 | International Flavors & Fragrances, Inc. | Ethyl 4-(thioacetoxy)butyrate as a flavoring agent and methods for preparing and using same |
| EP1275643A4 (de) | 2000-04-19 | 2009-06-03 | Chugai Pharmaceutical Co Ltd | Vitamin d derivate |
| NZ528622A (en) * | 2000-06-15 | 2005-05-27 | Chugai Pharmaceutical Co Ltd | Methods for preparing vitamin D derivatives that are useful for treating psoriasis |
| JP5932339B2 (ja) | 2009-01-27 | 2016-06-08 | バーグ エルエルシー | 化学療法に付随する副作用を軽減するためのビタミンｄ３およびその類似体 |
| IN2012DN02137A (de) | 2009-08-14 | 2015-08-07 | Berg Biosystems Llc | |
| SG10201709894RA (en) | 2013-05-29 | 2018-01-30 | Berg Llc | Preventing or mitigating chemotherapy induced alopecia using vitamin d |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3577552D1 (de) * | 1984-11-27 | 1990-06-13 | Chugai Pharmaceutical Co Ltd | Vitamin d-derivate und verfahren zu deren herstellung. |
| JPS61267550A (ja) | 1984-12-28 | 1986-11-27 | Chugai Pharmaceut Co Ltd | ９，１０−セコ−５，７，１０（１９）−プレグナトリエン誘導体 |
| JP3050564B2 (ja) * | 1989-12-15 | 2000-06-12 | 中外製薬株式会社 | 新規な２２―オキサビタミンｄ誘導体 |
| GB9007236D0 (en) | 1990-03-30 | 1990-05-30 | Leo Pharm Prod Ltd | Chemical compounds |
| JP2752506B2 (ja) * | 1990-07-26 | 1998-05-18 | 株式会社クラレ | １α―ヒドロキシタキステロール誘導体の製造方法 |
| DE4220757A1 (de) * | 1992-06-24 | 1994-01-05 | Schering Ag | Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln |
| GB9226877D0 (en) * | 1992-12-23 | 1993-02-17 | Leo Pharm Prod Ltd | Chemical compounds |
| JP4089473B2 (ja) * | 2003-03-12 | 2008-05-28 | 株式会社ジェイテクト | ブラケット一体型リザーブタンク |
-
1995
- 1995-04-10 KR KR1019960705708A patent/KR100244060B1/ko not_active IP Right Cessation
- 1995-04-10 EP EP95914550A patent/EP0755922B1/de not_active Expired - Lifetime
- 1995-04-10 AT AT95914550T patent/ATE195513T1/de not_active IP Right Cessation
- 1995-04-10 PT PT95914550T patent/PT755922E/pt unknown
- 1995-04-10 RU RU96121801A patent/RU2142941C1/ru not_active IP Right Cessation
- 1995-04-10 DE DE69518410T patent/DE69518410T2/de not_active Expired - Lifetime
- 1995-04-10 AU AU21482/95A patent/AU2148295A/en not_active Abandoned
- 1995-04-10 DK DK95914550T patent/DK0755922T3/da active
- 1995-04-10 ES ES95914550T patent/ES2150560T3/es not_active Expired - Lifetime
- 1995-04-10 CN CN95193058A patent/CN1046502C/zh not_active Expired - Fee Related
- 1995-04-10 WO PCT/JP1995/000699 patent/WO1995027697A1/ja active IP Right Grant
- 1995-04-10 US US08/718,499 patent/US5824811A/en not_active Expired - Lifetime
- 1995-04-10 BR BR9507355A patent/BR9507355A/pt not_active IP Right Cessation
-
2000
- 2000-09-01 GR GR20000402009T patent/GR3034322T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3034322T3 (en) | 2000-12-29 |
| RU2142941C1 (ru) | 1999-12-20 |
| US5824811A (en) | 1998-10-20 |
| WO1995027697A1 (fr) | 1995-10-19 |
| AU2148295A (en) | 1995-10-30 |
| KR970702245A (ko) | 1997-05-13 |
| EP0755922B1 (de) | 2000-08-16 |
| EP0755922A1 (de) | 1997-01-29 |
| BR9507355A (pt) | 1997-09-09 |
| EP0755922A4 (de) | 1997-07-02 |
| KR100244060B1 (ko) | 2000-02-01 |
| CN1046502C (zh) | 1999-11-17 |
| DK0755922T3 (da) | 2000-11-13 |
| ES2150560T3 (es) | 2000-12-01 |
| DE69518410D1 (de) | 2000-09-21 |
| ATE195513T1 (de) | 2000-09-15 |
| PT755922E (pt) | 2000-11-30 |
| CN1148380A (zh) | 1997-04-23 |
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| DE69518410D1 (de) | 22-thiavitamin-d3-derivate | |
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| PT947504E (pt) | Derivados de vitamina d 16-eno | |
| MX9604735A (es) | Derivados de la 22-tiavitamina d3. | |
| AU5156593A (en) | Vitamin d derivative and process for producing the same | |
| ATE140919T1 (de) | Indolderivate | |
| DE69615814T2 (de) | Uch-15-verbindungen | |
| ES2164258T3 (es) | Procedimiento de preparacion de derivados de carbamoilmetilurea. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |