DE69516048T2 - Elektrophoretische immunosubstraktion auf der kapillare zur klassifikation und typisierung von m-proteinen - Google Patents

Elektrophoretische immunosubstraktion auf der kapillare zur klassifikation und typisierung von m-proteinen

Info

Publication number
DE69516048T2
DE69516048T2 DE69516048T DE69516048T DE69516048T2 DE 69516048 T2 DE69516048 T2 DE 69516048T2 DE 69516048 T DE69516048 T DE 69516048T DE 69516048 T DE69516048 T DE 69516048T DE 69516048 T2 DE69516048 T2 DE 69516048T2
Authority
DE
Germany
Prior art keywords
immuno
typing
electrophoretic
subtraction
capillary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69516048T
Other languages
English (en)
Other versions
DE69516048D1 (de
Inventor
Hann-Ping Wang
Cheng-Ming Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of DE69516048D1 publication Critical patent/DE69516048D1/de
Publication of DE69516048T2 publication Critical patent/DE69516048T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/561—Immunoelectrophoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
DE69516048T 1994-01-25 1995-01-17 Elektrophoretische immunosubstraktion auf der kapillare zur klassifikation und typisierung von m-proteinen Expired - Lifetime DE69516048T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/186,347 US5567282A (en) 1994-01-25 1994-01-25 On-capillary electrophoretic immunosubtraction for classification and typing of M-proteins
PCT/US1995/000506 WO1995020160A2 (en) 1994-01-25 1995-01-17 On-capillary electrophoretic immunosubtraction for classification and typing of m-proteins

Publications (2)

Publication Number Publication Date
DE69516048D1 DE69516048D1 (de) 2000-05-11
DE69516048T2 true DE69516048T2 (de) 2000-10-12

Family

ID=22684588

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69516048T Expired - Lifetime DE69516048T2 (de) 1994-01-25 1995-01-17 Elektrophoretische immunosubstraktion auf der kapillare zur klassifikation und typisierung von m-proteinen

Country Status (6)

Country Link
US (1) US5567282A (de)
EP (1) EP0690988B1 (de)
JP (1) JPH08508576A (de)
DE (1) DE69516048T2 (de)
ES (1) ES2144604T3 (de)
WO (1) WO1995020160A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783397A (en) * 1995-12-11 1998-07-21 Northeastern University Screening natural samples for new therapeutic compounds using capillary electrophoresis
US5922184A (en) * 1997-07-21 1999-07-13 Bio-Rad Laboratories, Inc. Computer-directed detection of paraproteins
US6299747B1 (en) 1997-12-17 2001-10-09 Cetek Corporation Capillary electrophoretic methods to detect new biologically active compounds in complex biological material
US6156179A (en) * 1998-07-09 2000-12-05 Bio-Rad Laboratories Computer directed identification of paraproteins
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
FR2862134B1 (fr) * 2003-11-12 2007-07-27 Sebia Sa Analyse et typage de proteines monoclonales par electrophorese capillaire et immunodeplacement
JP5178070B2 (ja) * 2007-07-03 2013-04-10 日東紡績株式会社 糖化免疫グロブリンによる疾患の判定方法
EP2184606B1 (de) 2008-11-03 2015-06-24 Helena Laboratories (UK) Ltd. Immunverschiebungs-Elektrophorese
JP6207148B2 (ja) * 2012-11-15 2017-10-04 岸本　忠史 電気泳動装置、電気泳動法および電気泳動法を用いた濃縮・分離・分析方法
DK3276351T3 (da) 2016-07-27 2020-07-20 Sebia Sa Immunofixationselektroforese-fremgangsmåde med target-komponenter on-gel immunoforskydning
GB201709387D0 (en) * 2017-06-13 2017-07-26 Genetic Microdevices Ltd Method
WO2019209730A1 (en) * 2018-04-24 2019-10-31 Helena Laboratories Corporation Removal of interfering factors from serum protein electrophoresis profiles
CN113552370B (zh) * 2021-09-23 2021-12-28 北京小蝇科技有限责任公司 一种毛细管免疫分型单克隆免疫球蛋白定量分析方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59224565A (ja) * 1983-04-28 1984-12-17 Morinaga Milk Ind Co Ltd 抗原検出用試薬
US5139630A (en) * 1991-05-31 1992-08-18 Beckman Instruments, Inc. Identification of sample constituents utilizing capillary electrophoresis
US5120413A (en) * 1991-05-31 1992-06-09 Beckman Instruments, Inc. Analysis of samples utilzing capillary electrophoresis
US5228960A (en) * 1992-07-17 1993-07-20 Beckman Instruments, Inc. Analysis of samples by capillary electrophoretic immunosubtraction
IT1273311B (it) * 1993-02-19 1997-07-08 Lympus Optical Co Ltd Metodo per elaborazione di dati elettroforetici

Also Published As

Publication number Publication date
JPH08508576A (ja) 1996-09-10
EP0690988B1 (de) 2000-04-05
WO1995020160A2 (en) 1995-07-27
WO1995020160A3 (en) 1995-08-24
ES2144604T3 (es) 2000-06-16
EP0690988A1 (de) 1996-01-10
US5567282A (en) 1996-10-22
DE69516048D1 (de) 2000-05-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BECKMAN COULTER, INC., BREA, CALIF., US