DE69510780D1 - Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographie - Google Patents

Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographie

Info

Publication number
DE69510780D1
DE69510780D1 DE69510780T DE69510780T DE69510780D1 DE 69510780 D1 DE69510780 D1 DE 69510780D1 DE 69510780 T DE69510780 T DE 69510780T DE 69510780 T DE69510780 T DE 69510780T DE 69510780 D1 DE69510780 D1 DE 69510780D1
Authority
DE
Germany
Prior art keywords
column
known material
mixture
materials
passing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69510780T
Other languages
English (en)
Other versions
DE69510780T2 (de
Inventor
William Asher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SRI International Inc
Original Assignee
SRI International Inc
Stanford Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SRI International Inc, Stanford Research Institute filed Critical SRI International Inc
Application granted granted Critical
Publication of DE69510780D1 publication Critical patent/DE69510780D1/de
Publication of DE69510780T2 publication Critical patent/DE69510780T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/422—Displacement mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE69510780T 1994-04-05 1995-02-23 Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographie Expired - Fee Related DE69510780T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/223,165 US5427686A (en) 1994-04-05 1994-04-05 Process for separating material from mixture using displacement chromatography
PCT/US1995/002288 WO1995026795A1 (en) 1994-04-05 1995-02-23 Process for separating material from mixture using displacement chromatography

Publications (2)

Publication Number Publication Date
DE69510780D1 true DE69510780D1 (de) 1999-08-19
DE69510780T2 DE69510780T2 (de) 2000-01-13

Family

ID=22835333

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69510780T Expired - Fee Related DE69510780T2 (de) 1994-04-05 1995-02-23 Verfahren zur trennung eines materials von einer mischung durch verdrängungschromatographie

Country Status (7)

Country Link
US (1) US5427686A (de)
EP (1) EP0754083B1 (de)
JP (1) JPH10501885A (de)
AT (1) ATE182085T1 (de)
CA (1) CA2187090A1 (de)
DE (1) DE69510780T2 (de)
WO (1) WO1995026795A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5851400A (en) * 1997-03-21 1998-12-22 University Of Maryland At Baltimore County Method for eliminating the displacer in displacement chromatography of proteins
US6239262B1 (en) 1998-01-07 2001-05-29 Rensselaer Polytechnic Institute Low molecular weight displacers for protein purification in hydrophobic interaction and reversed phase chromatographic systems
US7141602B2 (en) * 1998-09-18 2006-11-28 Lek Pharmaceuticals D.D. Process for obtaining HMG-CoA reductase inhibitors of high purity
SI20072A (sl) * 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze
US6746695B1 (en) 1998-10-02 2004-06-08 Armadillo Pharmaceuticals, Inc. Pharmaceutical preparations of bioactive substances extracted from natural sources
GB9822963D0 (en) * 1998-10-20 1998-12-16 Agner Erik Improvements in or relating to chromatography
US6573373B1 (en) 1999-06-29 2003-06-03 Isis Pharmaceuticals, Inc. High affinity, low molecular weight displacers for oligonucleotide purification
US6610125B2 (en) 2001-10-23 2003-08-26 University Of Maine System Board Of Trustees Selective filtration and concentration of toxic nerve agents
WO2003074148A1 (en) 2002-02-28 2003-09-12 Rensselaer Polytechnic Institute High-affinity, low-molecular-mass displacers for ion-exchange chromatography
GB2439875B (en) * 2005-04-22 2010-10-20 Waters Investments Ltd Apparatus and methods for mass spectrometric directed purification of biopolymers
WO2009135656A1 (en) * 2008-05-06 2009-11-12 Lonza Biologics Plc. A method for the purification of antibodies using displacement chromatography
GB201115218D0 (en) * 2011-09-02 2011-10-19 Glaxo Group Ltd Novel process
CN105727912B (zh) * 2016-04-07 2018-08-17 湖北省农业科学院农业质量标准与检测技术研究所 一种新型胆固醇键合硅胶固定相及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920398A (en) * 1973-08-06 1975-11-18 Dow Chemical Co Method for chromatographic analysis of organic acids or their carboxylate salts
US3925019A (en) * 1973-08-06 1975-12-09 Dow Chemical Co Chromatographic analysis of ionic species
US3971842A (en) * 1974-08-08 1976-07-27 Atlantic Richfield Company Continuous displacement chromatographic separation
US4274967A (en) * 1978-07-07 1981-06-23 Technicon Instruments Corporation Chromatographic apparatus and method
AU536948B2 (en) * 1979-12-19 1984-05-31 Asahi Kasei Kogyo Kabushiki Kaisha Separation of rare earth metals
JPS59145022A (ja) * 1983-02-08 1984-08-20 Japan Atom Energy Res Inst リチウム同位体を分離する方法
JPS6075530A (ja) * 1983-09-30 1985-04-27 Asahi Chem Ind Co Ltd 金属元素の新しい分離精製方法
US4724081A (en) * 1986-04-28 1988-02-09 Soken Kagaku Kabushiki Kaisha Process and apparatus for separation by liquid chromatography
GB2223692A (en) * 1988-09-16 1990-04-18 Philips Nv Liquid chromatography
US5028696A (en) * 1988-10-28 1991-07-02 Torres Anthony R Ion exchange and separation method
US4915843A (en) * 1988-11-28 1990-04-10 Union Oil Company Of California Continuous displacement chromatographic method

Also Published As

Publication number Publication date
ATE182085T1 (de) 1999-07-15
JPH10501885A (ja) 1998-02-17
EP0754083B1 (de) 1999-07-14
DE69510780T2 (de) 2000-01-13
EP0754083A1 (de) 1997-01-22
WO1995026795A1 (en) 1995-10-12
CA2187090A1 (en) 1995-10-12
US5427686A (en) 1995-06-27

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee