DE69510772D1 - Verfahren zur quantifizierung von lbp in körperflüssigkeiten - Google Patents

Verfahren zur quantifizierung von lbp in körperflüssigkeiten

Info

Publication number
DE69510772D1
DE69510772D1 DE69510772T DE69510772T DE69510772D1 DE 69510772 D1 DE69510772 D1 DE 69510772D1 DE 69510772 T DE69510772 T DE 69510772T DE 69510772 T DE69510772 T DE 69510772T DE 69510772 D1 DE69510772 D1 DE 69510772D1
Authority
DE
Germany
Prior art keywords
lbp
quantifying
body liquids
quantifying lbp
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69510772T
Other languages
English (en)
Other versions
DE69510772T2 (de
Inventor
Mark White
Stephen Carroll
Jeremy Ma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xoma Technology Ltd USA
Original Assignee
Xoma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Corp filed Critical Xoma Corp
Application granted granted Critical
Publication of DE69510772D1 publication Critical patent/DE69510772D1/de
Publication of DE69510772T2 publication Critical patent/DE69510772T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/821—Chemistry: analytical and immunological testing involving complement factors or complement systems

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Peptides Or Proteins (AREA)
DE69510772T 1994-01-24 1995-01-24 Verfahren zur quantifizierung von lbp in körperflüssigkeiten Expired - Lifetime DE69510772T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/186,811 US5484705A (en) 1994-01-24 1994-01-24 Method for quantifying lipopolysaccharide binding protein
PCT/US1995/000982 WO1995020163A1 (en) 1994-01-24 1995-01-24 Method for quantifying lbp in body fluids

Publications (2)

Publication Number Publication Date
DE69510772D1 true DE69510772D1 (de) 1999-08-19
DE69510772T2 DE69510772T2 (de) 1999-11-11

Family

ID=22686373

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69510772T Expired - Lifetime DE69510772T2 (de) 1994-01-24 1995-01-24 Verfahren zur quantifizierung von lbp in körperflüssigkeiten

Country Status (13)

Country Link
US (3) US5484705A (de)
EP (1) EP0741870B1 (de)
JP (1) JP3554331B2 (de)
CN (1) CN1132013C (de)
AT (1) ATE182216T1 (de)
AU (1) AU701710B2 (de)
DE (1) DE69510772T2 (de)
DK (1) DK0741870T3 (de)
ES (1) ES2133738T3 (de)
GR (1) GR3031303T3 (de)
HK (1) HK1015174A1 (de)
MX (1) MX9602688A (de)
WO (1) WO1995020163A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5652332A (en) * 1993-03-12 1997-07-29 Xoma Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof
US5891618A (en) * 1994-01-24 1999-04-06 Xoma Corporation Method for quantifying LBP in body fluids
US5484705A (en) * 1994-01-24 1996-01-16 Xoma Corporation Method for quantifying lipopolysaccharide binding protein
US5932536A (en) * 1994-06-14 1999-08-03 The Rockefeller University Compositions for neutralization of lipopolysaccharides
EP0839156A1 (de) * 1995-07-20 1998-05-06 Xoma Corporation Peptide gegen pilzbefall
NZ332720A (en) * 1996-05-10 2000-07-28 Xoma Corp Therapeutic uses of bactericidal/permeability increasing (BPI) protein to treat human meningococcemia
AU736096B2 (en) * 1996-05-23 2001-07-26 Xoma Corporation Therapeutic uses of BPI protein products in humans with hemorrhage due to trauma
US5888973A (en) * 1996-08-09 1999-03-30 Xoma Corporation Anti-chlamydial uses of BPI protein products
US6482796B2 (en) 1996-11-01 2002-11-19 Xoma Corporation Therapeutic uses of N-terminal BPI protein products in ANCA-positive patients
US6093573A (en) * 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US5990082A (en) * 1997-10-22 1999-11-23 Xoma Corporation Uses of lipopolysaccharide binding protein
US6013631A (en) 1998-06-19 2000-01-11 Xoma Corporation Bactericidal/permeability-increasing protein (BPI) deletion analogs
US7465555B2 (en) * 2002-04-02 2008-12-16 Becton, Dickinson And Company Early detection of sepsis
CA2505785A1 (en) * 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
BR0316231A (pt) * 2002-11-12 2005-10-04 Becton Dickinson Co Métodos para determinar o estado de sepsia para prognosticar o começo de sepsia e para diagnosticar a sìndrome de resposta inflamatória sistêmica em um indivìduo e para isolar um biomarcador, perfil biomarcador r kit
WO2004044555A2 (en) * 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
US7191068B2 (en) * 2003-03-25 2007-03-13 Proteogenix, Inc. Proteomic analysis of biological fluids
US8068990B2 (en) * 2003-03-25 2011-11-29 Hologic, Inc. Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
US20060157647A1 (en) * 2005-01-18 2006-07-20 Becton, Dickinson And Company Multidimensional liquid chromatography/spectrometry
AU2006236588A1 (en) 2005-04-15 2006-10-26 Becton, Dickinson And Company Diagnosis of sepsis
ATE549129T1 (de) * 2007-04-26 2012-03-15 Adept Technology Inc Vakuumgreifvorrichtung
US8669113B2 (en) 2008-04-03 2014-03-11 Becton, Dickinson And Company Advanced detection of sepsis
US7846678B2 (en) * 2008-08-18 2010-12-07 BioDtech, Inc. Enhancing endotoxin detection
JP5674664B2 (ja) * 2008-09-04 2015-02-25 ベックマン コールター， インコーポレイテッド パンキナーゼ活性化およびシグナリング経路の評価
CN104407156B (zh) * 2014-12-05 2016-03-16 重庆中元生物技术有限公司 检测多糖结合蛋白(lbp)的胶乳增强免疫比浊试剂盒及其制备方法
CN109507323A (zh) * 2018-12-07 2019-03-22 上海浩港生物技术有限公司 一种用质谱仪检测人类血液中lbp含量的试剂盒
CN109507127A (zh) * 2018-12-07 2019-03-22 上海浩港生物技术有限公司 一种用于检测人类血液中lbp含量的试剂盒

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310879A (en) * 1985-04-30 1994-05-10 The Scripps Research Institute Antibodies which immunoreact with lapine lipopolysaccharide binding protein (LBP)
US5245013A (en) * 1985-04-30 1993-09-14 Richard Ulevitch Acute phase protein modulating endotoxic activity of lipopolysaccharides, assay methods and polypeptides
WO1986006279A1 (en) * 1985-04-30 1986-11-06 Scripps Clinic And Research Foundation Acute phase protein modulating endotoxic activity of lipopolysaccharides, compositions and methods
DE69032662T2 (de) * 1989-08-01 1999-03-11 Scripps Research Inst Verfahren und zusammensetzungen zur verbesserung der symptome von sepsis
JPH07502642A (ja) * 1991-09-26 1995-03-23 インサイト　ファーマシューティカルズ，インコーポレイテッド 新規な形態のリポ糖結合性タンパク質（ｌｂｐ）
AU6522794A (en) * 1993-03-22 1994-10-11 Incyte Pharmaceuticals, Inc. Use of bactericidal/permeability increasing protein and lipopolysaccharide binding protein levels and ratios thereof in diagnosis
CA2161971A1 (en) * 1993-04-30 1994-11-10 Randal W. Scott Recombinant bpi-based and lbp-based proteins, nucleic acid molecules encoding same, methods of producing same, and uses thereof
AU7175694A (en) * 1993-06-17 1995-01-17 Xoma Corporation Lipopolysaccharide binding protein derivatives
AU7330994A (en) * 1993-07-14 1995-02-13 Xoma Corporation Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products
US5484705A (en) * 1994-01-24 1996-01-16 Xoma Corporation Method for quantifying lipopolysaccharide binding protein

Also Published As

Publication number Publication date
GR3031303T3 (en) 1999-12-31
HK1015174A1 (en) 1999-10-08
AU1732195A (en) 1995-08-08
EP0741870B1 (de) 1999-07-14
DK0741870T3 (da) 1999-12-13
AU701710B2 (en) 1999-02-04
US6274328B1 (en) 2001-08-14
EP0741870A1 (de) 1996-11-13
JPH09508465A (ja) 1997-08-26
ES2133738T3 (es) 1999-09-16
US5804367A (en) 1998-09-08
MX9602688A (es) 1997-05-31
CN1139485A (zh) 1997-01-01
DE69510772T2 (de) 1999-11-11
US5484705A (en) 1996-01-16
ATE182216T1 (de) 1999-07-15
WO1995020163A1 (en) 1995-07-27
JP3554331B2 (ja) 2004-08-18
CN1132013C (zh) 2003-12-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: XOMA TECHNOLOGY LTD., BERKELEY, CALIF., US