DE69132144D1 - Menschliche phospholipase aktivierender proteinteil - Google Patents

Menschliche phospholipase aktivierender proteinteil

Info

Publication number
DE69132144D1
DE69132144D1 DE69132144T DE69132144T DE69132144D1 DE 69132144 D1 DE69132144 D1 DE 69132144D1 DE 69132144 T DE69132144 T DE 69132144T DE 69132144 T DE69132144 T DE 69132144T DE 69132144 D1 DE69132144 D1 DE 69132144D1
Authority
DE
Germany
Prior art keywords
activating protein
phospholipase
rheumatoid arthritis
sample
person
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69132144T
Other languages
English (en)
Inventor
John S Bomalaski
Mike A Clark
Robert G L Shorr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69132144D1 publication Critical patent/DE69132144D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69132144T 1990-12-06 1991-12-06 Menschliche phospholipase aktivierender proteinteil Expired - Lifetime DE69132144D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/626,589 US5294698A (en) 1990-12-06 1990-12-06 Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis
PCT/US1991/009302 WO1992010756A1 (en) 1990-12-06 1991-12-06 Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis

Publications (1)

Publication Number Publication Date
DE69132144D1 true DE69132144D1 (de) 2000-05-31

Family

ID=24511034

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132144T Expired - Lifetime DE69132144D1 (de) 1990-12-06 1991-12-06 Menschliche phospholipase aktivierender proteinteil

Country Status (8)

Country Link
US (4) US5294698A (de)
EP (1) EP0563244B1 (de)
JP (1) JPH06503647A (de)
AT (1) ATE192236T1 (de)
AU (1) AU9147391A (de)
CA (1) CA2097935A1 (de)
DE (1) DE69132144D1 (de)
WO (1) WO1992010756A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527775A (en) * 1994-10-13 1996-06-18 Enzon, Inc. Reduction of mammalian neoplasms with phospholipase A2 activating substances
US5668016A (en) * 1995-12-29 1997-09-16 Fernandez-Pol; Jose Alberto Method of preparing and activating samples for radioimmunoassay and other test
US5955287A (en) * 1995-12-29 1999-09-21 Fernandez-Pol; Jose Alberto Method of determining level of biological substances elevated in the presence of cancer and other neoplasms
KR20040011895A (ko) * 2002-07-31 2004-02-11 김대경 소의 뇌에서의 신규한 칼슘 비의존적 포스포리파아제 에이투 효소, 이의 용도 및 제조 방법
EP2280286A1 (de) * 2003-09-15 2011-02-02 Oklahoma Medical Research Foundation Verfahren zur Verwendung von Zytokin-Assays zur Diagnose, Behandlung und Beurteilung von Systemischem Lupus Erythematosus
JP4466684B2 (ja) * 2007-06-12 2010-05-26 トヨタ自動車株式会社 リアクトル
EP2418491A1 (de) * 2010-08-10 2012-02-15 Bioftalmik, S.L. Verfahren zur Diagnose von Xerophthalmie und Blepharitis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916056A (en) * 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
US5153166A (en) * 1988-08-18 1992-10-06 Trustees Of At Biochem Chromatographic stationary supports
JPH07196699A (ja) * 1993-12-28 1995-08-01 Unitika Ltd 抗ヒトホスホリパーゼエイツー活性化蛋白質抗体とこの抗体を産生するハイブリドーマ、並びにこの抗体を用いたヒトホスホリパーゼエイツー活性化蛋白質の測定用試薬及び測定方法
JPH07196698A (ja) * 1993-12-28 1995-08-01 Unitika Ltd 抗ヒトホスホリパーゼエイツー活性化蛋白質抗体とこの抗体を産生するハイブリドーマ、並びにこの抗体を用いたヒトホスホリパーゼエイツー活性化蛋白質の測定用試薬及び測定方法

Also Published As

Publication number Publication date
EP0563244B1 (de) 2000-04-26
US5367063A (en) 1994-11-22
CA2097935A1 (en) 1992-06-07
ATE192236T1 (de) 2000-05-15
US5294698A (en) 1994-03-15
US5786154A (en) 1998-07-28
EP0563244A1 (de) 1993-10-06
WO1992010756A1 (en) 1992-06-25
JPH06503647A (ja) 1994-04-21
US5580968A (en) 1996-12-03
AU9147391A (en) 1992-07-08
EP0563244A4 (en) 1995-03-29

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Legal Events

Date Code Title Description
8332 No legal effect for de