DE69503905D1 - Peptidderivate mit metallopeptidasehemmender aktivität - Google Patents

Peptidderivate mit metallopeptidasehemmender aktivität

Info

Publication number
DE69503905D1
DE69503905D1 DE69503905T DE69503905T DE69503905D1 DE 69503905 D1 DE69503905 D1 DE 69503905D1 DE 69503905 T DE69503905 T DE 69503905T DE 69503905 T DE69503905 T DE 69503905T DE 69503905 D1 DE69503905 D1 DE 69503905D1
Authority
DE
Germany
Prior art keywords
groups
carbon atoms
alkyl
alkyl moiety
mono
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69503905T
Other languages
English (en)
Other versions
DE69503905T2 (de
Inventor
Franco Pellacini
Gabriele Norcini
Daniela Botta
Stefano Romagnano
Francesco Santangelo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Publication of DE69503905D1 publication Critical patent/DE69503905D1/de
Application granted granted Critical
Publication of DE69503905T2 publication Critical patent/DE69503905T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
DE69503905T 1994-06-21 1995-06-02 Peptidderivate mit metallopeptidasehemmender aktivität Expired - Fee Related DE69503905T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941292A IT1270261B (it) 1994-06-21 1994-06-21 Derivati peptidici ad attivita' inibitrice delle metallopeptidasi
PCT/EP1995/002100 WO1995035307A1 (en) 1994-06-21 1995-06-02 Peptide derivatives with metallopeptidase inhibitory activity

Publications (2)

Publication Number Publication Date
DE69503905D1 true DE69503905D1 (de) 1998-09-10
DE69503905T2 DE69503905T2 (de) 1999-04-22

Family

ID=11369147

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69503905T Expired - Fee Related DE69503905T2 (de) 1994-06-21 1995-06-02 Peptidderivate mit metallopeptidasehemmender aktivität

Country Status (7)

Country Link
EP (1) EP0766694B1 (de)
AT (1) ATE169303T1 (de)
AU (1) AU2673795A (de)
DE (1) DE69503905T2 (de)
ES (1) ES2122627T3 (de)
IT (1) IT1270261B (de)
WO (1) WO1995035307A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201101672A1 (ru) 2009-05-28 2012-06-29 Новартис Аг Замещенные производные аминомасляной кислоты в качестве ингибиторов неприлизина
AU2010251967B9 (en) 2009-05-28 2014-04-03 Novartis Ag Substituted aminopropionic derivatives as neprilysin inhibitors
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
JP6301371B2 (ja) 2013-02-14 2018-04-11 ノバルティス アーゲー インビボ効力が改善されたｎｅｐ阻害剤としての置換ビスフェニルブタン酸誘導体
PE20151666A1 (es) 2013-02-14 2015-11-19 Novartis Ag Derivados sustituidos del acido bisfenil butanoico fosfonico como inhibidores de la nep

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8311286D0 (en) * 1983-04-26 1983-06-02 Searle & Co Carboxyalkyl peptide derivatives

Also Published As

Publication number Publication date
ITMI941292A1 (it) 1995-12-21
EP0766694A1 (de) 1997-04-09
AU2673795A (en) 1996-01-15
ITMI941292A0 (it) 1994-06-21
EP0766694B1 (de) 1998-08-05
DE69503905T2 (de) 1999-04-22
WO1995035307A1 (en) 1995-12-28
ES2122627T3 (es) 1998-12-16
IT1270261B (it) 1997-04-29
ATE169303T1 (de) 1998-08-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee