DE69511689D1 - Phosphonyldipeptide zur bekämpfung von kardiovasvakuläre erkrankungen - Google Patents

Phosphonyldipeptide zur bekämpfung von kardiovasvakuläre erkrankungen

Info

Publication number
DE69511689D1
DE69511689D1 DE69511689T DE69511689T DE69511689D1 DE 69511689 D1 DE69511689 D1 DE 69511689D1 DE 69511689 T DE69511689 T DE 69511689T DE 69511689 T DE69511689 T DE 69511689T DE 69511689 D1 DE69511689 D1 DE 69511689D1
Authority
DE
Germany
Prior art keywords
carbon atoms
alkyl
pct
groups
alkyl moiety
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69511689T
Other languages
English (en)
Other versions
DE69511689T2 (de
Inventor
Gabriele Norcini
Gabriele Morazzoni
Francesco Santangelo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Publication of DE69511689D1 publication Critical patent/DE69511689D1/de
Application granted granted Critical
Publication of DE69511689T2 publication Critical patent/DE69511689T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69511689T 1994-04-14 1995-04-11 Phosphonyldipeptide zur bekämpfung von kardiovasvakuläre erkrankungen Expired - Fee Related DE69511689T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI940696A IT1274673B (it) 1994-04-14 1994-04-14 Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari
PCT/EP1995/001322 WO1995028417A1 (en) 1994-04-14 1995-04-11 Phosphonyldipeptides useful in the treatment of cardiovascular diseases

Publications (2)

Publication Number Publication Date
DE69511689D1 true DE69511689D1 (de) 1999-09-30
DE69511689T2 DE69511689T2 (de) 2000-04-27

Family

ID=11368561

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69511689T Expired - Fee Related DE69511689T2 (de) 1994-04-14 1995-04-11 Phosphonyldipeptide zur bekämpfung von kardiovasvakuläre erkrankungen

Country Status (8)

Country Link
US (1) US5760285A (de)
EP (1) EP0755405B1 (de)
AT (1) ATE183750T1 (de)
AU (1) AU2305895A (de)
DE (1) DE69511689T2 (de)
ES (1) ES2136848T3 (de)
IT (1) IT1274673B (de)
WO (1) WO1995028417A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276161B1 (it) * 1995-11-23 1997-10-27 Zambon Spa Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
US6166052A (en) * 1998-03-11 2000-12-26 Warner-Lambert Company Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379146A (en) * 1981-02-17 1983-04-05 Merck & Co., Inc. Substituted phosphonamides as antihypertensives
US4432972A (en) * 1981-08-03 1984-02-21 E. R. Squibb & Sons, Inc. Phosphonamidate compounds
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare
FR2652087B1 (fr) * 1989-09-15 1993-10-15 Bioprojet Ste Civile Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques.
US5155100A (en) * 1991-05-01 1992-10-13 Ciba-Geigy Corporation Phosphono/biaryl substituted dipeptide derivatives
US5294632A (en) * 1991-05-01 1994-03-15 Ciba-Geigy Corporation Phosphono/biaryl substituted dipetide derivatives
JPH05105698A (ja) * 1991-06-13 1993-04-27 Takeda Chem Ind Ltd ホスホン酸誘導体、その製造法および用途
IT1254521B (it) * 1992-03-17 1995-09-25 Zambon Spa Derivati della 2-ammino-tetralina attivi sul sistema cardiovascolare

Also Published As

Publication number Publication date
WO1995028417A1 (en) 1995-10-26
ATE183750T1 (de) 1999-09-15
ITMI940696A0 (it) 1994-04-14
DE69511689T2 (de) 2000-04-27
EP0755405B1 (de) 1999-08-25
ITMI940696A1 (it) 1995-10-14
ES2136848T3 (es) 1999-12-01
AU2305895A (en) 1995-11-10
EP0755405A1 (de) 1997-01-29
IT1274673B (it) 1997-07-24
US5760285A (en) 1998-06-02

Similar Documents

Publication Publication Date Title
AU2884295A (en) Phosphinic acid derivatives with metallopeptidase inhibitory activity
AU550774B2 (en) 1-aryl-2-aminomethyl cyclopropane carboxylates
CA2036876A1 (fr) Derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ES8205771A1 (es) Un procedimiento para la obtencion de un derivado acilado sustituido de acido octahidro-1h-indol-2-carboxilico
BR9503582A (pt) Composto composiçao farmaceutica utilizaçao e método de tratamento de um ser humano
BR9307595A (pt) Composto, processo para sua preparação, composição herbicida, e, processo para danificar severamente ou exterminar plantas indesejáveis
AU2001272666A1 (en) 2-adamantylethylamines and their use in the treatment of conditions generally associated with abnormalities in glutamatergic transmission
DE3876813D1 (de) 3(2h)pyridazinon, verfahren zu dessen herstellung und dieses enthaltendes mittel gegen srs-a.
ID26622A (id) Senyawa-senyawa pengganti 2-benzylamino-2-phenyl-acetamide
MX9804295A (es) Compuestos farmaceuticamente utiles.
DE69726716T2 (de) Antikachektische zusammensetzung
MXPA04005940A (es) Acidos 3-(imidazolil)-2-aminopropanoicos.
ES472290A1 (es) Un procedimiento para preparar un compuesto de benceno di- sustituido en orto
DE69511689D1 (de) Phosphonyldipeptide zur bekämpfung von kardiovasvakuläre erkrankungen
DE59509582D1 (de) Alpha-(pyrazol-3-yl)-oxymethylen-phenylbutensäuremethylester und ihre verwendung zur bekämpfung von schadpilzen oder tierischen schädlingen
ATE169303T1 (de) Peptidderivate mit metallopeptidasehemmender aktivität
ES8307234A1 (es) "procedimiento para la preparacion de derivados de 1,2,3-tiadiazol-5-il-urea".
HU894471D0 (en) Process for the preparation of 15-amino-20,21-dinor-eburnamenine derivatives and pharmaceutical compositions containing them
ES433894A1 (es) Procedimiento para la preparacion de nuevas bencilaminas.
DK44779A (da) 2-chlorsulfinylazetidin-4-on-forbindelser til anvendelse som mellemprodukter ved fremstilling af 3-exomethylencephamsulfoxider

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee