DE69434810D1 - Immobilisiertes markierungsverfahren - Google Patents

Immobilisiertes markierungsverfahren

Info

Publication number
DE69434810D1
DE69434810D1 DE69434810T DE69434810T DE69434810D1 DE 69434810 D1 DE69434810 D1 DE 69434810D1 DE 69434810 T DE69434810 T DE 69434810T DE 69434810 T DE69434810 T DE 69434810T DE 69434810 D1 DE69434810 D1 DE 69434810D1
Authority
DE
Germany
Prior art keywords
pct
ligand
metal
support
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69434810T
Other languages
English (en)
Other versions
DE69434810T2 (de
Inventor
Alfred Pollak
Robert Dunn-Dufault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bracco International BV
Original Assignee
Bracco International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco International BV filed Critical Bracco International BV
Publication of DE69434810D1 publication Critical patent/DE69434810D1/de
Application granted granted Critical
Publication of DE69434810T2 publication Critical patent/DE69434810T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
DE69434810T 1993-11-16 1994-11-16 Immobilisiertes markierungsverfahren Expired - Fee Related DE69434810T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15268093A 1993-11-16 1993-11-16
US152680 1993-11-16
PCT/CA1994/000637 WO1995013832A1 (en) 1993-11-16 1994-11-16 Immobilized labelling method

Publications (2)

Publication Number Publication Date
DE69434810D1 true DE69434810D1 (de) 2006-09-14
DE69434810T2 DE69434810T2 (de) 2007-08-02

Family

ID=22543938

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434810T Expired - Fee Related DE69434810T2 (de) 1993-11-16 1994-11-16 Immobilisiertes markierungsverfahren

Country Status (8)

Country Link
US (1) US5789555A (de)
EP (1) EP0730472B1 (de)
JP (1) JP4293632B2 (de)
AT (1) ATE334704T1 (de)
AU (1) AU8137694A (de)
CA (1) CA2175557A1 (de)
DE (1) DE69434810T2 (de)
WO (1) WO1995013832A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789555A (en) * 1993-11-16 1998-08-04 Resolution Pharmaceuticals Inc. Immobilized labelling method
US5569745A (en) * 1994-02-25 1996-10-29 Resolution Pharmaceuticals Inc. Peptide-Chelator conjugates
US5662885A (en) * 1994-07-22 1997-09-02 Resolution Pharmaceuticals Inc. Peptide derived radionuclide chelators
US5804158A (en) * 1995-05-31 1998-09-08 Resolution Pharmaceuticals Inc. Sequestered imaging agents
US6770261B2 (en) * 1995-06-02 2004-08-03 Research Corporation Technologies Magnetic resonance imaging agents for the detection of physiological agents
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
US6872536B1 (en) 1998-11-10 2005-03-29 Bracco Imaging S.P.A. Chemotactic peptide antagonists for imaging sites of inflammation
US7320784B1 (en) 1999-02-17 2008-01-22 Bracco Imaging S.P.A. Immobilized labeling compounds and methods
US7109167B2 (en) * 2000-06-02 2006-09-19 Bracco International B.V. Compounds for targeting endothelial cells, compositions containing the same and methods for their use
US8263739B2 (en) * 2000-06-02 2012-09-11 Bracco Suisse Sa Compounds for targeting endothelial cells, compositions containing the same and methods for their use
CA2440656A1 (en) 2001-03-09 2002-09-19 Apollo Biotechnology, Inc. Conjugate probes and optical detection of analytes
WO2004022105A2 (en) * 2002-09-03 2004-03-18 University Of Zurich Preparation of m(co)3-complexes by solid phase techniques via metal assisted cleavage from the solid support
KR100612869B1 (ko) 2004-11-08 2006-08-14 삼성전자주식회사 고정화된 금속-리간드 복합체에 의한 세포 용해 방법
US7798998B2 (en) 2006-10-06 2010-09-21 Surgiquest, Inc. Elastically deformable surgical access device
KR101430627B1 (ko) 2008-05-13 2014-08-14 유니버시티 오브 캔사스 금속 추출 펩타이드(ｍａｐ) 태그 및 관련된 방법
MX350082B (es) * 2011-07-29 2017-08-24 Avelas Biosciences Inc Moleculas de entrega selectiva y metodos de uso.
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
WO2014176284A1 (en) * 2013-04-22 2014-10-30 Avelas Biosciences, Inc. Selective drug delivery compositions and methods of use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2727245C3 (de) * 1977-06-16 1980-06-26 Brintzinger, Hans, Prof. Dr., 7750 Konstanz Polymergebundene CyclopentadienylÜbergangsmetall-Verbindungen und ihre Ligand-Substitutions-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Katalysatoren
US4272503A (en) * 1978-05-25 1981-06-09 New England Nuclear Corporation Reductant composition for technetium-99m and method for making technetium-99m labelled ligands
US4305922A (en) * 1978-10-04 1981-12-15 University Patents, Inc. Labeling proteins with 99m-Tc by ligand exchange
US4659839A (en) * 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
SE8703682L (sv) * 1987-09-24 1989-03-25 Wallac Oy Homogen bestaemningsmetod som utnyttjar affinitetsreaktioner
US5059541A (en) * 1988-04-29 1991-10-22 Neorx Corporation Minimal derivatization of proteins
US4988496A (en) * 1988-05-31 1991-01-29 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
US5089249A (en) * 1988-06-10 1992-02-18 Neorx Corporation Conjugates for bone imaging and bone cancer therapy
US5162505A (en) * 1989-09-19 1992-11-10 Centocor Proteins modified with positively charged carriers and compositions prepared therefrom
US5206346A (en) * 1990-12-05 1993-04-27 E. I. Du Pont De Nemours And Company Method for iodination/purification
ATE168015T1 (de) * 1990-12-21 1998-07-15 Mallinckrodt Medical Inc Zur strahlensynovektomie nützliche radionukleotidmarkierte teilchen
FI88654C (fi) * 1991-03-15 1993-06-10 Datacity Center Oy Fluorescenshoejningsmetod
US5789555A (en) * 1993-11-16 1998-08-04 Resolution Pharmaceuticals Inc. Immobilized labelling method
US5480970A (en) * 1993-12-22 1996-01-02 Resolution Pharmaceuticals Metal chelators
US5569745A (en) * 1994-02-25 1996-10-29 Resolution Pharmaceuticals Inc. Peptide-Chelator conjugates

Also Published As

Publication number Publication date
JP4293632B2 (ja) 2009-07-08
WO1995013832A1 (en) 1995-05-26
ATE334704T1 (de) 2006-08-15
EP0730472B1 (de) 2006-08-02
JPH09505061A (ja) 1997-05-20
AU8137694A (en) 1995-06-06
EP0730472A1 (de) 1996-09-11
US5789555A (en) 1998-08-04
DE69434810T2 (de) 2007-08-02
CA2175557A1 (en) 1995-05-26

Similar Documents

Publication Publication Date Title
DE69434810D1 (de) Immobilisiertes markierungsverfahren
HU910155D0 (en) Process for the production borane acid adducts of rhenium-dioxime and technetium-99m-dioxime complexes containing biochemically active groups
ATE149730T1 (de) Verfahren zur volumenverminderung einer radioaktiver zusammensetzung
EP1028123A3 (de) Verfahren zur Herstellung von Metallocen-Verbindungen
GR3024598T3 (en) Metal complexes of acid adducts to dioxime ligands useful in labelling proteins and other amine-containing compounds
GB9304979D0 (en) Imobilisation and separation of cells and other particles
AU8424691A (en) Raw material briquette for mineral wool production and process for its preparation and its use
IS3966A (is) Aðferð til framleiðslu á lyfjablöndum sem innihalda nifedipine
Watkinson et al. Synthesis of a bis-manganese water splitting complex
IE830326L (en) Production of transition metal complexes
TW357312B (en) Method and apparatus for locating specific information from a plurality of information
FI933546A (fi) Kemisk process
ZA9710930B (en) Process for the production of metal-complex carboxylic acid amides
AU7699196A (en) Perfluoroalkylation method and reagent therefor
TW340112B (en) Process for the preparation of isobornyl (meth) acrylate
ATE264828T1 (de) Verfahren zur herstellung von biarylen
FR2750423B1 (fr) Procede d'hydrogenation asymetrique d'un compose cetonique
BG101894A (en) 4-aminoteirahydrobenzisoxazole or -isothiazole compounds
IL122004A0 (en) Producing process of (fluoroaryl) borane compound and producing process of tetrakis (fluoroaryl) borate derivative
IE880131L (en) Preparation of hydroxybiphenyls
DE69922052D1 (de) Immobilisierte marker-verbindungen und verfahren
GB9707741D0 (en) Process
ATE182487T1 (de) Vorrichtung und verfahren zum synthetisieren von makromolekülen
ATE190666T1 (de) Verfahren zur herstellung von glycolipiden
Chandrasekaran et al. Group VI metal carbonyl complexes of (amino) spirocyclic cyclotriphosphazenes

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: GROSSE, SCHUMACHER, KNAUER, VON HIRSCHHAUSEN, 8033

8339 Ceased/non-payment of the annual fee