DE69427130D1 - Ssi tyrphostine und pharmazeutische zusammensetzungen - Google Patents

Ssi tyrphostine und pharmazeutische zusammensetzungen

Info

Publication number
DE69427130D1
DE69427130D1 DE69427130T DE69427130T DE69427130D1 DE 69427130 D1 DE69427130 D1 DE 69427130D1 DE 69427130 T DE69427130 T DE 69427130T DE 69427130 T DE69427130 T DE 69427130T DE 69427130 D1 DE69427130 D1 DE 69427130D1
Authority
DE
Germany
Prior art keywords
ssi
pharmaceutical compositions
tyrphostine
methods
novel compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427130T
Other languages
English (en)
Other versions
DE69427130T2 (de
Inventor
Alexander Levitzki
Abraham Novogrodsky
Aviv Gazit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KUPOT HOLIM HEALTH INSURANCE I
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
KUPOT HOLIM HEALTH INSURANCE I
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KUPOT HOLIM HEALTH INSURANCE I, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical KUPOT HOLIM HEALTH INSURANCE I
Publication of DE69427130D1 publication Critical patent/DE69427130D1/de
Application granted granted Critical
Publication of DE69427130T2 publication Critical patent/DE69427130T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69427130T 1993-11-24 1994-11-23 Ssi tyrphostine und pharmazeutische zusammensetzungen Expired - Fee Related DE69427130T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL10773693A IL107736A (en) 1993-11-24 1993-11-24 Pharmaceutical composition for the prevention of septic shock and for the treatment of chronic inflammatory diseases
PCT/US1994/013535 WO1995014464A1 (en) 1993-11-24 1994-11-23 Ssi tyrphostins and pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE69427130D1 true DE69427130D1 (de) 2001-05-23
DE69427130T2 DE69427130T2 (de) 2002-01-03

Family

ID=11065497

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427130T Expired - Fee Related DE69427130T2 (de) 1993-11-24 1994-11-23 Ssi tyrphostine und pharmazeutische zusammensetzungen

Country Status (8)

Country Link
EP (1) EP0731697B1 (de)
JP (1) JPH10504014A (de)
AT (1) ATE200618T1 (de)
AU (1) AU702800B2 (de)
CA (1) CA2177289A1 (de)
DE (1) DE69427130T2 (de)
IL (1) IL107736A (de)
WO (1) WO1995014464A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981569A (en) * 1992-11-13 1999-11-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Substituted phenylacrylonitrile compounds and compositions thereof for the treatment of disease
WO1997011692A2 (en) * 1995-09-11 1997-04-03 Osteoarthritis Sciences, Inc. Protein tyrosine kinase inhibitors for treating osteoarthritis
IL119069A0 (en) * 1996-08-14 1996-11-14 Mor Research Applic Ltd Pharmaceutical composition comprising tyrphostins
US5854285A (en) * 1997-04-03 1998-12-29 Natpro, Inc. Protein kinase inhibitor
JP2002516634A (ja) * 1997-06-18 2002-06-04 ザ ロックフェラー ユニヴァーシティ 敗血性ショックおよび実験的関節炎の治療において有用な、抗体およびペプチドの同定方法およびその使用
EP1250137B1 (de) * 2000-01-24 2007-08-15 Genzyme Corporation Inhibitoren des jak/stat-weges und deren verwendung zur behandlung von allgemeiner primärer osteoarthritis
AU4820101A (en) 2000-04-13 2001-10-30 Hsc Res Dev Lp Novel compounds for modulating cell proliferation
EP1752446A3 (de) * 2000-04-13 2007-03-21 HSC Research and Development Limited Partnership Verbindungen für die Modulation der Proliferation von Zellen
WO2003065971A2 (en) * 2001-06-14 2003-08-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Non-myeloablative tolerogenic treatment with tyrphostins
WO2005049009A1 (en) * 2003-11-21 2005-06-02 The University Of Newcastle Research Associates Limited Methods and agents for inhibiting dynamin-dependent endocytosis
KR101170655B1 (ko) 2003-12-11 2012-08-03 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 세포 증식 질환 치료용 화합물
EP1727822A4 (de) 2004-03-26 2007-05-09 Hsc Res Dev Lp Neue verbindungen zur modulation der zellproliferation
RU2456265C2 (ru) 2006-03-31 2012-07-20 Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем Биологически доступная для перорального применения кофейная кислота, относящаяся к противоопухолевым лекарственным средствам
GB2458259A (en) * 2008-02-05 2009-09-16 Univ Aberdeen Neuroprotective 3-phenylacrylonitrile (3-PAN) derivatives
WO2010005807A2 (en) 2008-07-08 2010-01-14 Board Of Regents, The University Of Texas System Novel inhibitors of proliferation and activation of signal transducer and activator of transcription (stats)
EP2432465B1 (de) 2009-05-21 2015-07-22 Children's Medical Research Institute Verwendung dynamischer ringstabilisatoren

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6239558A (ja) * 1985-08-13 1987-02-20 Kanegafuchi Chem Ind Co Ltd α−シアノアクリル酸アミド誘導体
GB9004348D0 (en) * 1990-02-27 1990-04-25 Orion Yhtymae Oy New use of catechol derivatives and their physiologically acceptable salts and esters
AU632992B2 (en) * 1987-12-24 1993-01-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Pharmaceutical compositions comprising benzylidene- and cinnamylidene-malononitrile derivatives for the inhibition of proliferative processes in mammalian cells, certain such novel compounds and their preparation
US5217999A (en) * 1987-12-24 1993-06-08 Yissum Research Development Company Of The Hebrew University Of Jerusalem Styryl compounds which inhibit EGF receptor protein tyrosine kinase
WO1991016892A1 (en) * 1990-04-27 1991-11-14 Rorer International (Holdings), Inc. Styryl compounds which inhibit egf receptor protein tyrosine kinase
CA2080554A1 (en) * 1991-10-15 1993-04-16 Mitsubishi Chemical Corporation Styrene derivatives
AU6910994A (en) * 1993-05-14 1994-12-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods and compounds for inhibiting cell proliferative disorders characterized by abnormal (abl) activity

Also Published As

Publication number Publication date
AU1293595A (en) 1995-06-13
IL107736A0 (en) 1994-02-27
CA2177289A1 (en) 1995-06-01
JPH10504014A (ja) 1998-04-14
EP0731697A1 (de) 1996-09-18
EP0731697B1 (de) 2001-04-18
DE69427130T2 (de) 2002-01-03
ATE200618T1 (de) 2001-05-15
IL107736A (en) 2001-01-11
AU702800B2 (en) 1999-03-04
WO1995014464A1 (en) 1995-06-01

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee