ATE84724T1 - Gewisse paf-antagonist/antihistamin-mischungen und verfahren. - Google Patents
Gewisse paf-antagonist/antihistamin-mischungen und verfahren.Info
- Publication number
- ATE84724T1 ATE84724T1 AT89304068T AT89304068T ATE84724T1 AT E84724 T1 ATE84724 T1 AT E84724T1 AT 89304068 T AT89304068 T AT 89304068T AT 89304068 T AT89304068 T AT 89304068T AT E84724 T1 ATE84724 T1 AT E84724T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- certain
- antihistamine
- mixtures
- paf antagonist
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000003848 thrombocyte activating factor antagonist Substances 0.000 title abstract 2
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 title 1
- 230000001387 anti-histamine Effects 0.000 title 1
- 239000000739 antihistaminic agent Substances 0.000 title 1
- -1 diaryl tetrahydrofuran Chemical compound 0.000 abstract 2
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 229940066051 combinations of antihistamines Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N tetrahydrofuran Substances C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 1
- KYTREVLPRJOBEM-UHFFFAOYSA-N triazolo[4,5-i][1,2]benzodiazepine Chemical compound C1=CC2=CC=CN=NC2=C2C1=NN=N2 KYTREVLPRJOBEM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18653588A | 1988-04-27 | 1988-04-27 | |
| EP89304068A EP0345931B1 (de) | 1988-04-27 | 1989-04-24 | Gewisse PAF-Antagonist/Antihistamin-Mischungen und Verfahren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE84724T1 true ATE84724T1 (de) | 1993-02-15 |
Family
ID=22685331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89304068T ATE84724T1 (de) | 1988-04-27 | 1989-04-24 | Gewisse paf-antagonist/antihistamin-mischungen und verfahren. |
Country Status (15)
| Country | Link |
|---|---|
| EP (2) | EP0402422A1 (de) |
| JP (1) | JPH0655673B2 (de) |
| KR (1) | KR930009786B1 (de) |
| AT (1) | ATE84724T1 (de) |
| AU (1) | AU619555B2 (de) |
| CA (1) | CA1327316C (de) |
| DE (1) | DE68904475T2 (de) |
| DK (1) | DK255190A (de) |
| ES (1) | ES2044100T4 (de) |
| IE (1) | IE63697B1 (de) |
| IL (1) | IL90100A (de) |
| MY (1) | MY106956A (de) |
| NZ (1) | NZ228879A (de) |
| WO (1) | WO1989010143A1 (de) |
| ZA (1) | ZA893101B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH30676A (en) * | 1986-07-22 | 1997-09-16 | Boehringer Ingelhein Kg | Hetrazepine compounds which have useful pharmaceutical utility |
| US6277846B1 (en) * | 1990-05-31 | 2001-08-21 | Allergan Sales, Inc. | Use of platelet activating factor antagonists as anti-pruritic agents |
| US5227378A (en) * | 1990-08-02 | 1993-07-13 | Hoffmann-La Roche Inc. | Combination of PAF antagonists and LTD4 antagonists for the treatment of allergic reactions |
| EP0469477B1 (de) * | 1990-08-02 | 1995-09-20 | F. Hoffmann-La Roche Ag | Antiallergische Mischung |
| FR2673842B1 (fr) * | 1991-03-13 | 1993-12-24 | Rhone Poulenc Rorer Sa | Nouvelles compositions liquides a base de derives de la piperidine substitues en 1,4. |
| FR2684298B1 (fr) * | 1991-12-03 | 1994-03-11 | Rhone Poulenc Rorer Sa | Nouvelles compositions pharmaceutiques solides a base de derives de lapiperidine substitues en 1,4. |
| JP3060287B2 (ja) * | 1995-10-09 | 2000-07-10 | 参天製薬株式会社 | アパファントを主薬とする水性点眼剤 |
| DE10007203A1 (de) * | 2000-02-17 | 2001-08-23 | Asta Medica Ag | Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis |
| US8492376B2 (en) * | 2010-04-21 | 2013-07-23 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4539332A (en) * | 1983-11-14 | 1985-09-03 | Merck & Co., Inc. | 2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists |
| NZ211146A (en) * | 1984-02-29 | 1987-10-30 | Merck & Co Inc | 2,5-diaryl-tetrahydrothiophene derivatives and pharmaceutical compositions |
| US4595693A (en) * | 1984-06-04 | 1986-06-17 | Merck & Co., Inc. | Method of use of 2,5-diaryl tetrahydrofurans and analogs thereof as PAF-antagonists |
| DE3502392A1 (de) * | 1985-01-25 | 1986-07-31 | Boehringer Ingelheim KG, 6507 Ingelheim | Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen |
| US4910206A (en) * | 1986-07-14 | 1990-03-20 | Sandoz Pharmaceuticals Corp. | 5-hetero-or aryl-substituted-imidazo(2,1-a)isoquinolines and their use as PAF receptor antagonists |
-
1989
- 1989-04-24 JP JP1505865A patent/JPH0655673B2/ja not_active Expired - Lifetime
- 1989-04-24 EP EP89905952A patent/EP0402422A1/de active Pending
- 1989-04-24 AU AU35782/89A patent/AU619555B2/en not_active Ceased
- 1989-04-24 WO PCT/US1989/001671 patent/WO1989010143A1/en not_active Ceased
- 1989-04-24 EP EP89304068A patent/EP0345931B1/de not_active Expired - Lifetime
- 1989-04-24 KR KR1019890702438A patent/KR930009786B1/ko not_active Expired - Fee Related
- 1989-04-24 DE DE8989304068T patent/DE68904475T2/de not_active Expired - Fee Related
- 1989-04-24 ES ES89304068T patent/ES2044100T4/es not_active Expired - Lifetime
- 1989-04-24 AT AT89304068T patent/ATE84724T1/de not_active IP Right Cessation
- 1989-04-26 ZA ZA893101A patent/ZA893101B/xx unknown
- 1989-04-26 NZ NZ228879A patent/NZ228879A/en unknown
- 1989-04-26 CA CA000597855A patent/CA1327316C/en not_active Expired - Fee Related
- 1989-04-26 MY MYPI89000538A patent/MY106956A/en unknown
- 1989-04-26 IE IE136289A patent/IE63697B1/en not_active IP Right Cessation
- 1989-04-27 IL IL9010089A patent/IL90100A/en not_active IP Right Cessation
-
1990
- 1990-10-23 DK DK255190A patent/DK255190A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IE891362L (en) | 1989-10-27 |
| DE68904475T2 (de) | 1993-05-13 |
| KR930009786B1 (ko) | 1993-10-11 |
| DE68904475D1 (de) | 1993-03-04 |
| IE63697B1 (en) | 1995-05-31 |
| JPH03502097A (ja) | 1991-05-16 |
| WO1989010143A1 (en) | 1989-11-02 |
| CA1327316C (en) | 1994-03-01 |
| EP0345931B1 (de) | 1993-01-20 |
| NZ228879A (en) | 1992-08-26 |
| DK255190D0 (da) | 1990-10-23 |
| AU3578289A (en) | 1989-11-24 |
| IL90100A0 (en) | 1989-12-15 |
| KR900700136A (ko) | 1990-08-11 |
| EP0345931A1 (de) | 1989-12-13 |
| ZA893101B (en) | 1989-12-27 |
| ES2044100T4 (es) | 1996-07-16 |
| JPH0655673B2 (ja) | 1994-07-27 |
| IL90100A (en) | 1995-01-24 |
| ES2044100T3 (es) | 1994-01-01 |
| EP0402422A1 (de) | 1990-12-19 |
| DK255190A (da) | 1990-10-23 |
| AU619555B2 (en) | 1992-01-30 |
| MY106956A (en) | 1995-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |