DE69424288T2 - Partikel mit modifizierten physikalisch-chemischen eigenschaften, ihre herstellung und verwendung - Google Patents
Partikel mit modifizierten physikalisch-chemischen eigenschaften, ihre herstellung und verwendungInfo
- Publication number
- DE69424288T2 DE69424288T2 DE69424288T DE69424288T DE69424288T2 DE 69424288 T2 DE69424288 T2 DE 69424288T2 DE 69424288 T DE69424288 T DE 69424288T DE 69424288 T DE69424288 T DE 69424288T DE 69424288 T2 DE69424288 T2 DE 69424288T2
- Authority
- DE
- Germany
- Prior art keywords
- particles
- production
- chemical properties
- modified physical
- insecticides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title abstract 3
- 239000000126 substance Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003337 fertilizer Substances 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 230000035764 nutrition Effects 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
- C09K23/14—Derivatives of phosphoric acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Optics & Photonics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Nanotechnology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69424288T DE69424288T2 (de) | 1993-08-12 | 1994-08-09 | Partikel mit modifizierten physikalisch-chemischen eigenschaften, ihre herstellung und verwendung |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4327063A DE4327063A1 (de) | 1993-08-12 | 1993-08-12 | Ubidecarenon-Partikel mit modifizierten physikochemischen Eigenschaften |
PCT/SE1994/000728 WO1995005164A1 (en) | 1993-08-12 | 1994-08-09 | Particles with modified physicochemical properties, their preparation and uses |
DE69424288T DE69424288T2 (de) | 1993-08-12 | 1994-08-09 | Partikel mit modifizierten physikalisch-chemischen eigenschaften, ihre herstellung und verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69424288D1 DE69424288D1 (de) | 2000-06-08 |
DE69424288T2 true DE69424288T2 (de) | 2000-10-19 |
Family
ID=6495011
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE4327063A Withdrawn DE4327063A1 (de) | 1993-08-12 | 1993-08-12 | Ubidecarenon-Partikel mit modifizierten physikochemischen Eigenschaften |
DE69424288T Expired - Lifetime DE69424288T2 (de) | 1993-08-12 | 1994-08-09 | Partikel mit modifizierten physikalisch-chemischen eigenschaften, ihre herstellung und verwendung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE4327063A Withdrawn DE4327063A1 (de) | 1993-08-12 | 1993-08-12 | Ubidecarenon-Partikel mit modifizierten physikochemischen Eigenschaften |
Country Status (11)
Country | Link |
---|---|
US (1) | US6197349B1 (de) |
EP (1) | EP0711151B1 (de) |
JP (1) | JPH09502963A (de) |
AT (1) | ATE192333T1 (de) |
AU (1) | AU7392694A (de) |
DE (2) | DE4327063A1 (de) |
DK (1) | DK0711151T3 (de) |
ES (1) | ES2145146T3 (de) |
GR (1) | GR3033751T3 (de) |
PT (1) | PT711151E (de) |
WO (1) | WO1995005164A1 (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10311352A1 (de) * | 2003-03-14 | 2004-09-23 | Siemens Ag | Im HE(21 delta)-Mode anregbarer Resonator |
Families Citing this family (108)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030133955A1 (en) * | 1993-02-22 | 2003-07-17 | American Bioscience, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
US5439686A (en) * | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
US20070117862A1 (en) * | 1993-02-22 | 2007-05-24 | Desai Neil P | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
US5747001A (en) * | 1995-02-24 | 1998-05-05 | Nanosystems, L.L.C. | Aerosols containing beclomethazone nanoparticle dispersions |
DE69633222T2 (de) | 1995-02-24 | 2005-09-08 | Elan Pharma International Ltd. | Nanopartikel-dispersionen enthaltende aerosole |
DE19537027A1 (de) | 1995-10-05 | 1997-04-10 | Beiersdorf Ag | Hautpflegemittel für alte Haut |
WO1997030696A1 (fr) * | 1996-02-26 | 1997-08-28 | Daiichi Pharmaceutical Co., Ltd. | Liposome et dispersion de liposome |
US20070092563A1 (en) * | 1996-10-01 | 2007-04-26 | Abraxis Bioscience, Inc. | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
ES2159938T3 (es) * | 1997-02-11 | 2001-10-16 | Mse Pharmazeutika Gmbh | Preparados transdermicos, orales e intravenosos de 2,3-dimetoxi-5-metil-6-decaprenil-1,4-benzoquinona. |
US20030199425A1 (en) * | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
US8853260B2 (en) * | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
IT1296914B1 (it) * | 1997-12-01 | 1999-08-03 | Maria Rosa Gasco | Composizione farmaceutica comprendente microparticelle atte al passaggio transmucosale ed al superamento della barriera |
US7521068B2 (en) | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
DE19856432A1 (de) * | 1998-12-08 | 2000-06-15 | Basf Ag | Nanopartikuläre Kern-Schale Systeme sowie deren Verwendung in pharmazeutischen und kosmetischen Zubereitungen |
US6200550B1 (en) * | 1998-12-11 | 2001-03-13 | Q-Pharma, Inc. | Oral care compositions comprising coenzyme Q10 |
DE19905880A1 (de) * | 1999-02-11 | 2000-08-17 | Mse Pharmazeutika Gmbh | Spray enthaltend Ubichinon Qn |
DE19905879A1 (de) * | 1999-02-11 | 2000-08-17 | Mse Pharmazeutika Gmbh | Ubichinon Qn zur Behandlung von Schmerzen |
US20040034107A1 (en) * | 1999-02-11 | 2004-02-19 | Mse Pharmazeutika Gmbh | Ubiquinone Qn for the treatment of pain |
US6616942B1 (en) * | 1999-03-29 | 2003-09-09 | Soft Gel Technologies, Inc. | Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing |
DE19926168A1 (de) * | 1999-06-09 | 2000-12-14 | Beiersdorf Ag | Stylingmittel auf Alkoholbasis mit Biochinonen |
DE19926156A1 (de) * | 1999-06-09 | 2000-12-14 | Beiersdorf Ag | Haarkosmetische Zubereitungen insbesondere solche zur Verbesserung der Kämmbarkeit der Haare auf der Grundlage von Ubichinonen |
US6555139B2 (en) * | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
SG98393A1 (en) | 2000-05-19 | 2003-09-19 | Inst Materials Research & Eng | Injectable drug delivery systems with cyclodextrin-polymer based hydrogels |
DE10046541A1 (de) | 2000-09-19 | 2002-03-28 | Knoll Ag | Mechanisch stabile darreichungsformen, enthaltend Ubichinone |
US6403116B1 (en) | 2000-11-03 | 2002-06-11 | Triarco Inductries, Inc. | Coenzyme Q10 formulation |
US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
EP1269994A3 (de) * | 2001-06-22 | 2003-02-12 | Pfizer Products Inc. | Pharmazeutische Zusammensetzungen die ein Arzneimittel und die Konzentration verbesserende Polymere enthalten |
WO2003000236A1 (en) * | 2001-06-23 | 2003-01-03 | Lyotropic Therapeutics, Inc | Particles with improved solubilization capacity |
JP2004536136A (ja) | 2001-07-27 | 2004-12-02 | エヌ・ヴイ・ヌートリシア | 敗血症の防止及び/又は処置のための経腸組成物 |
US20080305173A1 (en) * | 2001-07-31 | 2008-12-11 | Beuford Arlie Bogue | Amorphous drug beads |
AU2002323168A1 (en) | 2001-09-05 | 2003-03-18 | Rensselaer Polytechnic Institute | Passivated nanoparticles, method of fabrication thereof, and devices incorporating nanoparticles |
US20060003012A9 (en) | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
JP2005504090A (ja) | 2001-09-26 | 2005-02-10 | バクスター・インターナショナル・インコーポレイテッド | 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製 |
DE10151392A1 (de) * | 2001-10-18 | 2003-05-08 | Bayer Cropscience Ag | Pulverförmige Feststoff-Formulierungen |
WO2003041632A2 (en) | 2001-11-14 | 2003-05-22 | Texas Tech University | Eutectic-based self-nanoemulsified drug delivery system |
ES2278984T3 (es) * | 2001-11-22 | 2007-08-16 | Firmenich Sa | Microcapsulas perfumantes o saborizantes que comprenden un agente ignifugo. |
ATE403432T1 (de) | 2002-02-01 | 2008-08-15 | Pfizer Prod Inc | Pharmazeutische darreichungsform mit gesteuerter freigabe eines cholesterylester- transferproteininhibitors |
CN1633245A (zh) * | 2002-02-14 | 2005-06-29 | Dsmip资产有限公司 | 水可分散的辅酶q10干粉 |
WO2003075900A2 (de) * | 2002-03-09 | 2003-09-18 | Mse Pharmazeutika Gmbh | Verwendung von ubichinonen zur beeinflussung der histaminwirkung zur behandlung von bronchitis, asthma, allergischen krankheiten |
DE10214031A1 (de) * | 2002-03-27 | 2004-02-19 | Pharmatech Gmbh | Verfahren zur Herstellung und Anwendung von Mikro- und Nanoteilchen durch aufbauende Mikronisation |
EP1551457A1 (de) * | 2002-07-16 | 2005-07-13 | Elan Pharma International Limited | Flüssige dosierzusammensetzungen von stabilen wirkstoffen in nanoteilchenform |
ITMI20021725A1 (it) * | 2002-08-01 | 2002-10-31 | Zambon Spa | Composizioni farmaceutiche ad attivita' antibiotica. |
CA2496441C (en) | 2002-08-12 | 2010-03-16 | Pfizer Products Inc. | Pharmaceutical compositions of semi-ordered drugs and polymers |
AU2003299590B8 (en) | 2002-12-09 | 2010-04-08 | Abraxis Bioscience, Llc | Compositions and methods of delivery of pharmacological agents |
WO2004062602A2 (en) * | 2003-01-09 | 2004-07-29 | Arizeke Pharmaceuticals Inc. | Compositions and methods for targeted biological delivery of molecular carriers |
CN100594023C (zh) * | 2003-02-03 | 2010-03-17 | 诺瓦提斯公司 | 药物制剂 |
JP2007515361A (ja) * | 2003-03-06 | 2007-06-14 | レンセラー・ポリテクニック・インスティチュート | ナノ粒子の、室温におけるバルク固体からの迅速な生成 |
JP4481928B2 (ja) * | 2003-03-11 | 2010-06-16 | 株式会社カネカ | コエンザイムq▲10▼を含有した水中油型乳化組成物、及びその製法 |
DE10312763A1 (de) * | 2003-03-21 | 2004-09-30 | IFAC Institut für angewandte Colloidtechnologie GmbH & Co. KG | Verfahren zur Herstellung einer SLN-Dispersion |
US7438903B2 (en) * | 2003-06-06 | 2008-10-21 | Nbty, Inc. | Methods and compositions that enhance bioavailability of coenzyme-Q10 |
CH715855B1 (de) * | 2003-08-28 | 2020-08-14 | Mibelle Ag | Zubereitung bestehend aus mindestens zwei Nanoemulsionen. |
WO2005032278A1 (en) | 2003-09-29 | 2005-04-14 | Soft Gel Technologies, Inc. | SOLUBILIZED CoQ-10 |
US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
US7713440B2 (en) * | 2003-10-08 | 2010-05-11 | Lyotropic Therapeutics, Inc. | Stabilized uncoated particles of reversed liquid crystalline phase materials |
MXPA06008293A (es) * | 2004-01-22 | 2007-06-11 | Univ Miami | Formulaciones topicas de coenzima q10 y metodos de uso. |
US7354980B1 (en) | 2004-03-12 | 2008-04-08 | Key Medical Technologies, Inc. | High refractive index polymers for ophthalmic applications |
WO2005095950A1 (en) * | 2004-03-30 | 2005-10-13 | Pfizer Products Inc. | Method and device for evaluation of pharmaceutical compositions |
US7803366B2 (en) | 2004-05-07 | 2010-09-28 | Nbty, Inc. | Methods and compositions that enhance bioavailability of coenzyme-Q10 |
US7446157B2 (en) | 2004-12-07 | 2008-11-04 | Key Medical Technologies, Inc. | Nanohybrid polymers for ophthalmic applications |
NZ563946A (en) | 2005-06-03 | 2012-02-24 | Acrux Dds Pty Ltd | Testosterone containing non-occlusive transdermal drug delivery composition for application to the arm pit / axilla |
EP1905064A2 (de) * | 2005-06-24 | 2008-04-02 | Applied Nanoworks, Inc. | Nanopartikel und verfahren zu ihrer herstellung |
WO2007016435A2 (en) * | 2005-07-28 | 2007-02-08 | Isp Investments Inc. | Method to improve characteristics of spray dried powders and granulated materials, and the products thereby produced |
AU2006280511A1 (en) * | 2005-08-12 | 2007-02-22 | Astrazeneca Ab | Process |
WO2008054508A2 (en) * | 2006-04-13 | 2008-05-08 | Alza Corporation | Stable nanosized amorphous drug |
US8491888B2 (en) * | 2006-05-05 | 2013-07-23 | Softgel Formulators, Inc. | Highly absorbable coenzyme Q10 composition and method of producing same |
US20080181957A1 (en) * | 2006-06-23 | 2008-07-31 | Min Wei | Increased amorphous stability of poorly water soluble drugs by nanosizing |
US20080245769A1 (en) * | 2006-07-17 | 2008-10-09 | Applied Nanoworks, Inc. | Nanoparticles and method of making thereof |
WO2008065502A1 (en) * | 2006-11-29 | 2008-06-05 | Pfizer Products Inc. | Pharmaceutical compositions based on a) nanoparticles comprising enteric polymers and b) casein |
US20080152717A1 (en) * | 2006-12-14 | 2008-06-26 | Isp Investments, Inc. | Amorphous valsartan and the production thereof |
US8613946B2 (en) * | 2006-12-21 | 2013-12-24 | Isp Investment Inc. | Carotenoids of enhanced bioavailability |
WO2008092046A2 (en) * | 2007-01-26 | 2008-07-31 | Isp Investments Inc. | Amorphous oxcarbazepine and the production thereof |
CN101622302B (zh) * | 2007-01-26 | 2013-01-23 | Isp投资公司 | 生产喷雾干燥产品的制剂工艺方法 |
TW200848039A (en) * | 2007-02-09 | 2008-12-16 | Astrazeneca Ab | Pharmaceutical compositions |
JP2010517759A (ja) * | 2007-02-09 | 2010-05-27 | アストラゼネカ・アクチエボラーグ | 水性媒体中における固体非晶質サブミクロン粒子の安定な分散体を製造する方法 |
US8343541B2 (en) | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
WO2008125940A2 (en) * | 2007-04-17 | 2008-10-23 | Pfizer Products Inc. | Nanoparticles comprising non-crystalline drug |
WO2008135855A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
WO2008135828A2 (en) * | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
US20100080852A1 (en) * | 2007-05-03 | 2010-04-01 | Ronald Arthur Beyerinck | Phamaceutical composition comprising nanoparticles and casein |
WO2008149230A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate |
US8974827B2 (en) * | 2007-06-04 | 2015-03-10 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
US20100215747A1 (en) * | 2007-07-13 | 2010-08-26 | Corey Jay Bloom | Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers |
KR100790957B1 (ko) | 2007-09-06 | 2008-01-04 | 영남대학교 산학협력단 | 코-엔자임 q 경구용 고형제제 조성물 |
US9233078B2 (en) * | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
EP2231169B1 (de) * | 2007-12-06 | 2016-05-04 | Bend Research, Inc. | Pharmazeutische zusammensetzungen mit nanopartikeln und resuspensionsmaterial |
ES2403193T3 (es) | 2008-02-05 | 2013-05-16 | Laboratorios Bago S.A. | Composiciones que comprenden alprazolam para el tratamiento del insomnio primario y del insomnio asociado con estados de ansiedad y procedimientos para su preparación |
CA2721071C (en) | 2008-04-11 | 2017-10-17 | Cytotech Labs, Llc | Methods and use of inducing apoptosis in cancer cells |
JP5687187B2 (ja) * | 2008-04-30 | 2015-03-18 | シーカ・テクノロジー・アーゲー | エポキシ樹脂組成物のための活性剤 |
WO2009135865A1 (de) * | 2008-05-09 | 2009-11-12 | Basf Se | Verfahren zur herstellung von partikeln enthaltend agrochemische wirkstoffe in amorpher form |
CA2730760A1 (en) * | 2008-07-16 | 2010-01-21 | Surmodics Pharmaceuticals, Inc. | Process for preparing microparticles containing bioactive peptides |
JP2012506904A (ja) | 2008-10-28 | 2012-03-22 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 難水溶性成分のためのメソ多孔性材料賦形剤 |
WO2010075065A2 (en) * | 2008-12-15 | 2010-07-01 | Banner Pharmacaps, Inc. | Methods for enhancing the release and absorption of water insoluble active agents |
KR101066197B1 (ko) * | 2009-04-06 | 2011-09-20 | 한국생명공학연구원 | 코엔자임 q10 나노입자, 그 제조방법 및 상기 나노입자를 포함하는 조성물 |
JP6081195B2 (ja) | 2009-05-11 | 2017-02-15 | バーグ エルエルシー | エピメタボリックシフター、多次元細胞内分子、または環境影響因子を使用する腫瘍性障害の診断のための方法 |
AU2010260208B2 (en) | 2009-06-16 | 2014-11-13 | Bristol-Myers Squibb Holdings Ireland Unlimited Company | Dosage forms of apixaban |
KR101779910B1 (ko) | 2009-10-22 | 2017-09-21 | 비쭈리 헬스 사이언스 엘엘씨 | 플라보노이드를 함유하는 조성물을 제조하는 방법 및 그의 사용 방법 |
EP2544663B1 (de) | 2010-03-12 | 2018-01-03 | Berg LLC | Intravenöse formulierung aus dem coenzym q10 (coq10) und verwendungsverfahren dafür |
DE102010021688A1 (de) * | 2010-05-27 | 2011-12-01 | Qineva Gmbh & Co. Kg | Verfahren zur Herstellung eines micellaren Wirkstoffkonzentrats |
CN103608323B (zh) | 2011-04-04 | 2016-08-17 | 博格有限责任公司 | 治疗中枢神经系统肿瘤的方法 |
EP2510930A1 (de) | 2011-04-15 | 2012-10-17 | Bionanoplus, S.L. | Nanopartikel mit Halbestern aus Poly(Methylvinylether-Co-Maleinsäureanhydrid) und Verwendungen davon |
PE20180414A1 (es) | 2011-06-17 | 2018-03-01 | Berg Llc | Composiciones farmaceuticas inhalables |
WO2013090452A1 (en) | 2011-12-12 | 2013-06-20 | Orbis Biosciences, Inc. | Sustained release particle formulations |
US10933032B2 (en) | 2013-04-08 | 2021-03-02 | Berg Llc | Methods for the treatment of cancer using coenzyme Q10 combination therapies |
IL276423B2 (en) | 2013-09-04 | 2024-05-01 | Berg Llc | Pharmaceutical preparations containing coenzyme Q10 for use in cancer treatment |
KR101499867B1 (ko) * | 2014-04-22 | 2015-03-06 | 에스케이케미칼주식회사 | 활성 성분 (i) 함유 조성물 및 이의 제조 방법 |
EP3103440A1 (de) | 2015-06-12 | 2016-12-14 | INDENA S.p.A. | Feste dispersionen von coenzym q10 |
CN111135142A (zh) * | 2020-01-16 | 2020-05-12 | 兰州大学 | 一种异甘草素纳米乳及其制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
JPS6168412A (ja) | 1984-09-10 | 1986-04-08 | Fujisawa Pharmaceut Co Ltd | 医薬品の凍結乾燥方法 |
DE3524788A1 (de) * | 1985-07-11 | 1987-01-22 | Lentia Gmbh | Stabile, intravenoes applizierbare, waessrige fettemulsion und ein verfahren zu deren herstellung |
-
1993
- 1993-08-12 DE DE4327063A patent/DE4327063A1/de not_active Withdrawn
-
1994
- 1994-08-09 EP EP94923855A patent/EP0711151B1/de not_active Expired - Lifetime
- 1994-08-09 AU AU73926/94A patent/AU7392694A/en not_active Abandoned
- 1994-08-09 DE DE69424288T patent/DE69424288T2/de not_active Expired - Lifetime
- 1994-08-09 WO PCT/SE1994/000728 patent/WO1995005164A1/en active IP Right Grant
- 1994-08-09 DK DK94923855T patent/DK0711151T3/da active
- 1994-08-09 AT AT94923855T patent/ATE192333T1/de active
- 1994-08-09 PT PT94923855T patent/PT711151E/pt unknown
- 1994-08-09 ES ES94923855T patent/ES2145146T3/es not_active Expired - Lifetime
- 1994-08-09 JP JP7506899A patent/JPH09502963A/ja active Pending
-
1997
- 1997-11-06 US US08/968,899 patent/US6197349B1/en not_active Expired - Lifetime
-
2000
- 2000-06-22 GR GR20000401446T patent/GR3033751T3/el not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10311352A1 (de) * | 2003-03-14 | 2004-09-23 | Siemens Ag | Im HE(21 delta)-Mode anregbarer Resonator |
Also Published As
Publication number | Publication date |
---|---|
DE4327063A1 (de) | 1995-02-16 |
ES2145146T3 (es) | 2000-07-01 |
DK0711151T3 (da) | 2000-08-14 |
ATE192333T1 (de) | 2000-05-15 |
US6197349B1 (en) | 2001-03-06 |
EP0711151B1 (de) | 2000-05-03 |
EP0711151A1 (de) | 1996-05-15 |
DE69424288D1 (de) | 2000-06-08 |
JPH09502963A (ja) | 1997-03-25 |
PT711151E (pt) | 2000-10-31 |
GR3033751T3 (en) | 2000-10-31 |
WO1995005164A1 (en) | 1995-02-23 |
AU7392694A (en) | 1995-03-14 |
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Owner name: MSE PHARMAZEUTIKA GMBH, 61352 BAD HOMBURG, DE |