DE69424209D1 - Tumorsuppressor-Gen Merlin und dessen Verwendungen - Google Patents

Tumorsuppressor-Gen Merlin und dessen Verwendungen

Info

Publication number
DE69424209D1
DE69424209D1 DE69424209T DE69424209T DE69424209D1 DE 69424209 D1 DE69424209 D1 DE 69424209D1 DE 69424209 T DE69424209 T DE 69424209T DE 69424209 T DE69424209 T DE 69424209T DE 69424209 D1 DE69424209 D1 DE 69424209D1
Authority
DE
Germany
Prior art keywords
merlin
tumor suppressor
suppressor gene
diagnosis
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69424209T
Other languages
English (en)
Other versions
DE69424209T2 (de
Inventor
James A Trofatter
Mia M Maccollin
James F Gusella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE69424209D1 publication Critical patent/DE69424209D1/de
Publication of DE69424209T2 publication Critical patent/DE69424209T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69424209T 1993-02-25 1994-02-25 Tumorsuppressor-Gen Merlin und dessen Verwendungen Expired - Fee Related DE69424209T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2203493A 1993-02-25 1993-02-25
US2606393A 1993-03-04 1993-03-04
US10880893A 1993-08-19 1993-08-19
US08/171,718 US5707863A (en) 1993-02-25 1993-12-22 Tumor suppressor gene merlin

Publications (2)

Publication Number Publication Date
DE69424209D1 true DE69424209D1 (de) 2000-06-08
DE69424209T2 DE69424209T2 (de) 2001-01-25

Family

ID=27487063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69424209T Expired - Fee Related DE69424209T2 (de) 1993-02-25 1994-02-25 Tumorsuppressor-Gen Merlin und dessen Verwendungen

Country Status (10)

Country Link
US (2) US5707863A (de)
EP (1) EP0613945B1 (de)
JP (1) JPH07143884A (de)
AT (1) ATE192489T1 (de)
CA (1) CA2115404A1 (de)
DE (1) DE69424209T2 (de)
DK (1) DK0613945T3 (de)
ES (1) ES2148283T3 (de)
GR (1) GR3034057T3 (de)
PT (1) PT613945E (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578462A (en) * 1994-01-10 1996-11-26 Bristol-Myers Squibb Company NF2 isoforms
WO1997039122A2 (en) * 1996-04-12 1997-10-23 Muro Pharmaceutical, Inc. ISOLATED AND CLONED MAST CELL 78 kDa PHOSPHOPROTEIN (MAST CELL DEGRANULATION INHIBITORY AGENT) AND USE THEREOF
US7053200B1 (en) 1999-06-01 2006-05-30 Baylor College Of Medicine Compositions and methods for the therapeutic use of an atonal-associated sequence for deafness, osteoarthritis, and abnormal cell proliferation
DE60045350D1 (de) 1999-06-01 2011-01-20 Baylor College Medicine Zusammensetzungen und verfahren zur therapeutischen anwendung einer mit dem gen atonal assoziierten sequenz
AU6181200A (en) * 1999-07-29 2001-02-19 Helix Research Institute Stomach cancer-associated gene
WO2001053529A2 (en) * 2000-01-20 2001-07-26 Genome Therapeutics Corporation RAPID DETERMINATION OF GENE STRUCTURE USING cDNA SEQUENCE
ES2291246T3 (es) * 2000-06-27 2008-03-01 Von Recklinghausen Gesellschaft E.V. Procedimiento para adquirir datos para el diagnostico presintomatico o prenatal de neurofribromatosis del tipo 1.
US20040014699A1 (en) * 2002-07-18 2004-01-22 Isis Pharmaceuticals, Inc. Antisense modulation of PTPRM expression
US20040249023A1 (en) * 2003-01-17 2004-12-09 Stoffer James O. Compounds for corrosion resistant primer coatings and protection of metal substrates
EP2771489B1 (de) * 2011-10-28 2018-07-04 Millennium Pharmaceuticals, Inc. Biomarker der reaktion auf nae-inhibitoren
TWI710635B (zh) 2014-10-09 2020-11-21 美商珍維克公司 編碼人類無調同源物-1(hath1)之腺病毒載體
CN110846309B (zh) * 2018-08-20 2023-03-24 中国农业科学院兰州兽医研究所 用于鉴定多房棘球绦虫引物对、引物探针组以及他们的应用
JP2024515629A (ja) * 2021-04-14 2024-04-10 リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル ニューロフィブロミン２／マーリン（ｎｆ２）遺伝子療法のための材料及び方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2045129A1 (en) * 1989-02-01 1990-08-02 Alfred I. Geller Herpes simplex virus type i expression vector
AU2468992A (en) * 1991-08-16 1993-03-16 General Hospital Corporation, The Method of gene delivery to post-mitotic cells
US5578462A (en) * 1994-01-10 1996-11-26 Bristol-Myers Squibb Company NF2 isoforms

Also Published As

Publication number Publication date
JPH07143884A (ja) 1995-06-06
ES2148283T3 (es) 2000-10-16
DE69424209T2 (de) 2001-01-25
DK0613945T3 (da) 2000-09-25
US5707863A (en) 1998-01-13
CA2115404A1 (en) 1994-08-26
PT613945E (pt) 2000-10-31
EP0613945B1 (de) 2000-05-03
US6077685A (en) 2000-06-20
ATE192489T1 (de) 2000-05-15
EP0613945A2 (de) 1994-09-07
GR3034057T3 (en) 2000-11-30
EP0613945A3 (de) 1996-01-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee