DE69421536D1 - Selektives dehalogenierungsverfahren - Google Patents

Selektives dehalogenierungsverfahren

Info

Publication number
DE69421536D1
DE69421536D1 DE69421536T DE69421536T DE69421536D1 DE 69421536 D1 DE69421536 D1 DE 69421536D1 DE 69421536 T DE69421536 T DE 69421536T DE 69421536 T DE69421536 T DE 69421536T DE 69421536 D1 DE69421536 D1 DE 69421536D1
Authority
DE
Germany
Prior art keywords
selective dehalogenation
procedure
general formula
dehalogenation procedure
compound represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69421536T
Other languages
English (en)
Other versions
DE69421536T2 (de
Inventor
Toshifumi Akiba
Takanobu Ikeya
Hirofumi Kawanishi
Yusuke Daiichi Pharma Yukimoto
Shinji Daiichi Pharma Kamihara
Tsutomu Daiichi Pharmace Ebata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69421536D1 publication Critical patent/DE69421536D1/de
Publication of DE69421536T2 publication Critical patent/DE69421536T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DE69421536T 1993-08-05 1994-08-03 Selektives dehalogenierungsverfahren Expired - Lifetime DE69421536T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19442393 1993-08-05
PCT/JP1994/001280 WO1995004712A1 (fr) 1993-08-05 1994-08-03 Procede de deshalogenation selective

Publications (2)

Publication Number Publication Date
DE69421536D1 true DE69421536D1 (de) 1999-12-09
DE69421536T2 DE69421536T2 (de) 2000-07-06

Family

ID=16324364

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69421536T Expired - Lifetime DE69421536T2 (de) 1993-08-05 1994-08-03 Selektives dehalogenierungsverfahren

Country Status (8)

Country Link
US (1) US5780669A (de)
EP (1) EP0712831B1 (de)
AT (1) ATE186292T1 (de)
DE (1) DE69421536T2 (de)
DK (1) DK0712831T3 (de)
ES (1) ES2140547T3 (de)
GR (1) GR3032474T3 (de)
WO (1) WO1995004712A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09124556A (ja) 1995-08-30 1997-05-13 Dai Ichi Seiyaku Co Ltd ハロゲン化シクロプロパン誘導体の製造方法
DE19620798A1 (de) * 1996-05-23 1997-11-27 Bayer Ag Verfahren zur Herstellung von 2-Fluor-1-cyclopropancarbonsäure und Derivaten davon durch reduktive Enthalogenierung
US6984768B2 (en) 2002-05-21 2006-01-10 Battelle Energy Alliance, Llc Method for destroying halocarbon compositions using a critical solvent
WO2004060851A1 (ja) * 2003-01-07 2004-07-22 Daiichi Pharmaceutical Co., Ltd. 還元的脱ハロゲン化方法
EP1731499B1 (de) * 2004-03-31 2014-10-01 Daiichi Sankyo Company, Limited Verfahren zur herstellung einer 1,2-cis-2-fluorcyclopropan-1-carbonsäureesterverbindung
JP4584625B2 (ja) * 2004-05-20 2010-11-24 第一三共株式会社 １，２−シス−２−フルオロシクロプロパン−１−カルボン酸エステル類の製法
CN106316824B (zh) * 2016-08-18 2018-10-19 广州康瑞泰药业有限公司 一种合成2-氟环丙烷甲酸的新方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3824433A1 (de) * 1988-07-19 1990-01-25 Bayer Ag Fluorcyclopropyl-derivate
JP3159537B2 (ja) * 1992-08-21 2001-04-23 第一製薬株式会社 ２−フルオロシクロプロパンカルボン酸の製法
JP3326215B2 (ja) * 1992-11-20 2002-09-17 第一製薬株式会社 還元的脱ハロゲン化法

Also Published As

Publication number Publication date
EP0712831A1 (de) 1996-05-22
ES2140547T3 (es) 2000-03-01
WO1995004712A1 (fr) 1995-02-16
GR3032474T3 (en) 2000-05-31
EP0712831A4 (de) 1996-09-25
DK0712831T3 (da) 2000-04-03
US5780669A (en) 1998-07-14
EP0712831B1 (de) 1999-11-03
ATE186292T1 (de) 1999-11-15
DE69421536T2 (de) 2000-07-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition