ATE186292T1 - Selektives dehalogenierungsverfahren - Google Patents
Selektives dehalogenierungsverfahrenInfo
- Publication number
- ATE186292T1 ATE186292T1 AT94923063T AT94923063T ATE186292T1 AT E186292 T1 ATE186292 T1 AT E186292T1 AT 94923063 T AT94923063 T AT 94923063T AT 94923063 T AT94923063 T AT 94923063T AT E186292 T1 ATE186292 T1 AT E186292T1
- Authority
- AT
- Austria
- Prior art keywords
- dehalogenation process
- selective dehalogenation
- general formula
- compound represented
- producing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000005695 dehalogenation reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Chemical group 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19442393 | 1993-08-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE186292T1 true ATE186292T1 (de) | 1999-11-15 |
Family
ID=16324364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94923063T ATE186292T1 (de) | 1993-08-05 | 1994-08-03 | Selektives dehalogenierungsverfahren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5780669A (de) |
| EP (1) | EP0712831B1 (de) |
| AT (1) | ATE186292T1 (de) |
| DE (1) | DE69421536T2 (de) |
| DK (1) | DK0712831T3 (de) |
| ES (1) | ES2140547T3 (de) |
| GR (1) | GR3032474T3 (de) |
| WO (1) | WO1995004712A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09124556A (ja) | 1995-08-30 | 1997-05-13 | Dai Ichi Seiyaku Co Ltd | ハロゲン化シクロプロパン誘導体の製造方法 |
| DE19620798A1 (de) * | 1996-05-23 | 1997-11-27 | Bayer Ag | Verfahren zur Herstellung von 2-Fluor-1-cyclopropancarbonsäure und Derivaten davon durch reduktive Enthalogenierung |
| US6984768B2 (en) | 2002-05-21 | 2006-01-10 | Battelle Energy Alliance, Llc | Method for destroying halocarbon compositions using a critical solvent |
| CN1304356C (zh) * | 2003-01-07 | 2007-03-14 | 第一制药株式会社 | 还原脱卤方法 |
| JP4891068B2 (ja) * | 2004-03-31 | 2012-03-07 | 第一三共株式会社 | １，２−シス−２−フルオロシクロプロパン−１−カルボン酸エステル類の製造法 |
| JP4584625B2 (ja) * | 2004-05-20 | 2010-11-24 | 第一三共株式会社 | １，２−シス−２−フルオロシクロプロパン−１−カルボン酸エステル類の製法 |
| CN106316824B (zh) * | 2016-08-18 | 2018-10-19 | 广州康瑞泰药业有限公司 | 一种合成2-氟环丙烷甲酸的新方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3824433A1 (de) * | 1988-07-19 | 1990-01-25 | Bayer Ag, 5090 Leverkusen | Fluorcyclopropyl-derivate |
| JP3159537B2 (ja) * | 1992-08-21 | 2001-04-23 | 第一製薬株式会社 | ２−フルオロシクロプロパンカルボン酸の製法 |
| JP3326215B2 (ja) * | 1992-11-20 | 2002-09-17 | 第一製薬株式会社 | 還元的脱ハロゲン化法 |
-
1994
- 1994-08-03 WO PCT/JP1994/001280 patent/WO1995004712A1/ja not_active Ceased
- 1994-08-03 AT AT94923063T patent/ATE186292T1/de active
- 1994-08-03 EP EP94923063A patent/EP0712831B1/de not_active Expired - Lifetime
- 1994-08-03 DE DE69421536T patent/DE69421536T2/de not_active Expired - Lifetime
- 1994-08-03 US US08/592,402 patent/US5780669A/en not_active Expired - Lifetime
- 1994-08-03 DK DK94923063T patent/DK0712831T3/da active
- 1994-08-03 ES ES94923063T patent/ES2140547T3/es not_active Expired - Lifetime
-
2000
- 2000-01-25 GR GR20000400168T patent/GR3032474T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0712831B1 (de) | 1999-11-03 |
| EP0712831A1 (de) | 1996-05-22 |
| ES2140547T3 (es) | 2000-03-01 |
| US5780669A (en) | 1998-07-14 |
| DE69421536D1 (de) | 1999-12-09 |
| DK0712831T3 (da) | 2000-04-03 |
| DE69421536T2 (de) | 2000-07-06 |
| EP0712831A4 (de) | 1996-09-25 |
| WO1995004712A1 (en) | 1995-02-16 |
| GR3032474T3 (en) | 2000-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |