DE69419503T2 - Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungen - Google Patents

Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungen

Info

Publication number
DE69419503T2
DE69419503T2 DE69419503T DE69419503T DE69419503T2 DE 69419503 T2 DE69419503 T2 DE 69419503T2 DE 69419503 T DE69419503 T DE 69419503T DE 69419503 T DE69419503 T DE 69419503T DE 69419503 T2 DE69419503 T2 DE 69419503T2
Authority
DE
Germany
Prior art keywords
fluorocarbon
fluorocoline
emulsions
lung
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69419503T
Other languages
English (en)
Other versions
DE69419503D1 (de
Inventor
Jeffrey Weers
Ernest Schutt
Timothy Pelura
Peter Keipert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alliance Pharmaceutical Corp
Original Assignee
Alliance Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alliance Pharmaceutical Corp filed Critical Alliance Pharmaceutical Corp
Application granted granted Critical
Publication of DE69419503D1 publication Critical patent/DE69419503D1/de
Publication of DE69419503T2 publication Critical patent/DE69419503T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69419503T 1993-03-16 1994-03-01 Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungen Expired - Fee Related DE69419503T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/032,333 US5635538A (en) 1993-03-16 1993-03-16 Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
PCT/US1994/002222 WO1994021227A1 (en) 1993-03-16 1994-03-01 Fluorocarbon emulsions with reduced pulmonary gas-trapping properties

Publications (2)

Publication Number Publication Date
DE69419503D1 DE69419503D1 (de) 1999-08-19
DE69419503T2 true DE69419503T2 (de) 1999-11-18

Family

ID=21864383

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69419503T Expired - Fee Related DE69419503T2 (de) 1993-03-16 1994-03-01 Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungen

Country Status (10)

Country Link
US (1) US5635538A (de)
EP (1) EP0689422B1 (de)
JP (1) JPH08507786A (de)
AT (1) ATE182071T1 (de)
AU (1) AU679052B2 (de)
DE (1) DE69419503T2 (de)
DK (1) DK0689422T3 (de)
ES (1) ES2133546T3 (de)
GR (1) GR3030793T3 (de)
WO (1) WO1994021227A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2679150A1 (fr) * 1991-07-17 1993-01-22 Atta Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations.
US5628930A (en) * 1992-10-27 1997-05-13 Alliance Pharmaceutical Corp. Stabilization of fluorocarbon emulsions
DE69831248T2 (de) * 1997-02-28 2006-04-13 The Regents Of The University Of California, Oakland Verfahren und zusammensetzungen zur optimierung des sauerstofftransportes in zellfreien systemen
US5814601A (en) * 1997-02-28 1998-09-29 The Regents Of The University Of California Methods and compositions for optimization of oxygen transport by cell-free systems
US6420143B1 (en) 1998-02-13 2002-07-16 Caliper Technologies Corp. Methods and systems for performing superheated reactions in microscale fluidic systems
US20030153491A1 (en) * 2002-01-11 2003-08-14 Winslow Robert M. Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
US20050164915A1 (en) * 2002-04-01 2005-07-28 Sangart, Inc. Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
ES2305368T3 (es) * 2002-05-10 2008-11-01 THE PROCTER & GAMBLE COMPANY Tisu estampado en relieve que tiene fibras superficiales sueltas y metodo para su produccion.
JP3912206B2 (ja) * 2002-07-05 2007-05-09 株式会社日立製作所 筒内直接燃料噴射装置用燃料ポンプ
DK1558226T3 (da) 2002-10-11 2012-05-07 Baxter Int Fremgangsmåde til cardiobeskyttelse og neurobeskyttelse ved intravenøs indgivelse af halogenerede, flygtige anæstetika
US20090117207A1 (en) * 2005-11-29 2009-05-07 Zoltani Csaba K Methods and compositions for treatment of poison-caused pathology
CN101448485B (zh) * 2006-05-22 2013-01-09 联合制药公司 用于血液替代品和其他治疗用途的优化的氟碳乳剂

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975512A (en) * 1970-12-21 1976-08-17 University Of Illinois Foundation Non-toxic brominated perfluorocarbons radiopaque agents
FR2515198A1 (fr) * 1981-10-22 1983-04-29 Centre Nat Rech Scient Microemulsions aqueuses de fluorocarbures indefiniment stables a une temperature donnee, procede d'obtention et application a titre de transporteurs d'oxygene
FR2523956A1 (fr) * 1982-03-26 1983-09-30 Ugine Kuhlmann Bis-(perfluoroalkyl)-1,2-ethenes ramifies, leur preparation et leur utilisation comme transporteurs d'oxygene convertisseur electromecanique
US4640833A (en) * 1983-02-28 1987-02-03 Adamantech, Inc. Use of perfluorobromoalkyl ethers as X-ray contrast agents
GB8504916D0 (en) * 1985-02-26 1985-03-27 Isc Chemicals Ltd Emulsions of perfluorocarbons in aqueous media
US5080885A (en) * 1986-01-14 1992-01-14 Alliance Pharmaceutical Corp. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
US4895876A (en) * 1987-03-20 1990-01-23 Air Products And Chemicals, Inc. Concentrated stable fluorochemical aqueous emulsions containing triglycerides
US4866096A (en) * 1987-03-20 1989-09-12 Air Products And Chemicals, Inc. Stable fluorochemical aqueous emulsions
EP0480925B1 (de) * 1989-07-05 1997-09-24 Alliance Pharmaceutical Corporation Fluorkohlenstoffemulsionen mit gesättigten phospholipidemulgatoren
DE4019062A1 (de) * 1989-08-30 1991-03-07 Kali Chemie Ag Stabilisierung von perfluorcarbonemulsionen und als emulsionsstabilisierende zusaetze verwendbare perfluorierte heterocyclische verbindungen
FR2679150A1 (fr) * 1991-07-17 1993-01-22 Atta Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations.
US5264220A (en) * 1991-11-12 1993-11-23 Long David M Jr Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents

Also Published As

Publication number Publication date
GR3030793T3 (en) 1999-11-30
ATE182071T1 (de) 1999-07-15
JPH08507786A (ja) 1996-08-20
DK0689422T3 (da) 1999-12-06
AU6356694A (en) 1994-10-11
DE69419503D1 (de) 1999-08-19
AU679052B2 (en) 1997-06-19
EP0689422A1 (de) 1996-01-03
WO1994021227A1 (en) 1994-09-29
ES2133546T3 (es) 1999-09-16
EP0689422B1 (de) 1999-07-14
US5635538A (en) 1997-06-03

Similar Documents

Publication Publication Date Title
DE69419503T2 (de) Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungen
ATE183099T1 (de) Konvertierbare mikroemulsionsverbindungen
ES2072452T3 (es) Medios cosmeticos desodorizantes.
KR890700018A (ko) 화장료
DE69420967T2 (de) Lösung zur verwendung gegen den pilzbefall von nägeln
ATE79016T1 (de) Kosmetische praeparate.
DE69400332D1 (de) Gel-ähnliche Zusammensetzung enthaltend Organopolysiloxane, ohne Geliermittel zur Kosmetische und Dermatologische Anwendung
DE69701965D1 (de) Verfahren zur modifizierung des befehlsatzes in einer smartkarte
DK0680699T3 (da) Varmestabile olie-i-vand-emulsioner stabiliseret medhydrolysater
MX9206150A (es) Agentes antiinflamatorios de derivados de tripeptidos
KR900000335A (ko) 히드록시알킬시스테인 유도체 및 이를 함유하는 거담제
BR9709570A (pt) Melhoramentos no efeito de herbicidas
KR910003095A (ko) 사람의 단백질 c변이체 및 이의 제조방법
CA2156922A1 (en) Fluorocarbon emulsions with reduced pulmonary gas-trapping properties
FI893042A0 (fi) Fiskodlingsfoerfarande.
ATE550076T1 (de) Kosmetische zubereitungen mit stabilisierten konservierungsmitteln
KR900001853A (ko) 변형된 인간 psti
KR970064587A (ko) 육모제(育毛劑)
SE7709195L (sv) Fungicid
AU4861690A (en) Sulfur-containing acrylic esters and fungicides containing them
JPS6463342A (en) Stabilization of glutathione-containing composition
KR830005839A (ko) 치마조성물(齒磨組成物)
ES2160249T3 (es) Mezclas fungicidas.
AU1248792A (en) Influenza virus vaccine composition having a synergistic effect and containing influenza virus core as an additive
KR900014598A (ko) 변형된 pe_40의 제조

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee