ATE182071T1 - Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungen - Google Patents
Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungenInfo
- Publication number
- ATE182071T1 ATE182071T1 AT94910799T AT94910799T ATE182071T1 AT E182071 T1 ATE182071 T1 AT E182071T1 AT 94910799 T AT94910799 T AT 94910799T AT 94910799 T AT94910799 T AT 94910799T AT E182071 T1 ATE182071 T1 AT E182071T1
- Authority
- AT
- Austria
- Prior art keywords
- fluorocarbon
- lungs
- trapping properties
- reduced gas
- less
- Prior art date
Links
- NBVXSUQYWXRMNV-UHFFFAOYSA-N fluoromethane Chemical compound FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 title abstract 5
- 239000000839 emulsion Substances 0.000 title abstract 3
- 210000004072 lung Anatomy 0.000 title 1
- 230000014759 maintenance of location Effects 0.000 abstract 2
- 210000000056 organ Anatomy 0.000 abstract 2
- 230000002685 pulmonary effect Effects 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/032,333 US5635538A (en) | 1993-03-16 | 1993-03-16 | Fluorocarbon emulsions with reduced pulmonary gas-trapping properties |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE182071T1 true ATE182071T1 (de) | 1999-07-15 |
Family
ID=21864383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94910799T ATE182071T1 (de) | 1993-03-16 | 1994-03-01 | Fluorkohlenstoff-emulsionen mit reduzierten gaseinschliessenden eigenschaften in den lungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5635538A (de) |
| EP (1) | EP0689422B1 (de) |
| JP (1) | JPH08507786A (de) |
| AT (1) | ATE182071T1 (de) |
| AU (1) | AU679052B2 (de) |
| DE (1) | DE69419503T2 (de) |
| DK (1) | DK0689422T3 (de) |
| ES (1) | ES2133546T3 (de) |
| GR (1) | GR3030793T3 (de) |
| WO (1) | WO1994021227A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2679150A1 (fr) * | 1991-07-17 | 1993-01-22 | Atta | Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations. |
| US5628930A (en) | 1992-10-27 | 1997-05-13 | Alliance Pharmaceutical Corp. | Stabilization of fluorocarbon emulsions |
| US5814601A (en) * | 1997-02-28 | 1998-09-29 | The Regents Of The University Of California | Methods and compositions for optimization of oxygen transport by cell-free systems |
| JP4583510B2 (ja) * | 1997-02-28 | 2010-11-17 | ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 無細胞系による酸素輸送の最適化のための方法と組成物 |
| US6420143B1 (en) | 1998-02-13 | 2002-07-16 | Caliper Technologies Corp. | Methods and systems for performing superheated reactions in microscale fluidic systems |
| US20030153491A1 (en) * | 2002-01-11 | 2003-08-14 | Winslow Robert M. | Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
| US20050164915A1 (en) * | 2002-04-01 | 2005-07-28 | Sangart, Inc. | Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
| EP1365068B1 (de) * | 2002-05-10 | 2008-05-07 | The Procter & Gamble Company | Geprägtes Tissue mit abstehenden Oberflächenfasern und Verfahren zu dessen Herstellung |
| JP3912206B2 (ja) * | 2002-07-05 | 2007-05-09 | 株式会社日立製作所 | 筒内直接燃料噴射装置用燃料ポンプ |
| HK1079703A1 (zh) | 2002-10-11 | 2006-04-13 | 巴克斯特国际公司 | 通过静脉施用卤化挥发性麻醉药保护心脏和保护神经的方法 |
| US20090117207A1 (en) * | 2005-11-29 | 2009-05-07 | Zoltani Csaba K | Methods and compositions for treatment of poison-caused pathology |
| JP5205369B2 (ja) * | 2006-05-22 | 2013-06-05 | アライアンス ファーマシューティカル コーポレイション | 血液代替のため、および他の治療的使用のための、最適化フルオロカーボンエマルジョン |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3975512A (en) * | 1970-12-21 | 1976-08-17 | University Of Illinois Foundation | Non-toxic brominated perfluorocarbons radiopaque agents |
| FR2515198A1 (fr) * | 1981-10-22 | 1983-04-29 | Centre Nat Rech Scient | Microemulsions aqueuses de fluorocarbures indefiniment stables a une temperature donnee, procede d'obtention et application a titre de transporteurs d'oxygene |
| FR2523956A1 (fr) * | 1982-03-26 | 1983-09-30 | Ugine Kuhlmann | Bis-(perfluoroalkyl)-1,2-ethenes ramifies, leur preparation et leur utilisation comme transporteurs d'oxygene convertisseur electromecanique |
| US4640833A (en) * | 1983-02-28 | 1987-02-03 | Adamantech, Inc. | Use of perfluorobromoalkyl ethers as X-ray contrast agents |
| GB8504916D0 (en) * | 1985-02-26 | 1985-03-27 | Isc Chemicals Ltd | Emulsions of perfluorocarbons in aqueous media |
| US4865836A (en) * | 1986-01-14 | 1989-09-12 | Fluoromed Pharmaceutical, Inc. | Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport |
| US5080885A (en) * | 1986-01-14 | 1992-01-14 | Alliance Pharmaceutical Corp. | Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport |
| US4987154A (en) * | 1986-01-14 | 1991-01-22 | Alliance Pharmaceutical Corp. | Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use |
| US4895876A (en) * | 1987-03-20 | 1990-01-23 | Air Products And Chemicals, Inc. | Concentrated stable fluorochemical aqueous emulsions containing triglycerides |
| US4866096A (en) * | 1987-03-20 | 1989-09-12 | Air Products And Chemicals, Inc. | Stable fluorochemical aqueous emulsions |
| WO1991000110A1 (en) * | 1989-07-05 | 1991-01-10 | Alliance Pharmaceutical Corp. | Fluorocarbon emulsions having saturated phospholipid emulsifiers |
| DE4019062A1 (de) * | 1989-08-30 | 1991-03-07 | Kali Chemie Ag | Stabilisierung von perfluorcarbonemulsionen und als emulsionsstabilisierende zusaetze verwendbare perfluorierte heterocyclische verbindungen |
| FR2679150A1 (fr) * | 1991-07-17 | 1993-01-22 | Atta | Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations. |
| US5264220A (en) * | 1991-11-12 | 1993-11-23 | Long David M Jr | Method of extending the vascular dwell-time of particulate therapeutic and particulate diagnostic agents |
-
1993
- 1993-03-16 US US08/032,333 patent/US5635538A/en not_active Expired - Lifetime
-
1994
- 1994-03-01 JP JP6521057A patent/JPH08507786A/ja not_active Ceased
- 1994-03-01 DE DE69419503T patent/DE69419503T2/de not_active Expired - Fee Related
- 1994-03-01 ES ES94910799T patent/ES2133546T3/es not_active Expired - Lifetime
- 1994-03-01 EP EP94910799A patent/EP0689422B1/de not_active Expired - Lifetime
- 1994-03-01 AT AT94910799T patent/ATE182071T1/de not_active IP Right Cessation
- 1994-03-01 WO PCT/US1994/002222 patent/WO1994021227A1/en not_active Ceased
- 1994-03-01 AU AU63566/94A patent/AU679052B2/en not_active Ceased
- 1994-03-01 DK DK94910799T patent/DK0689422T3/da active
-
1999
- 1999-07-15 GR GR990401830T patent/GR3030793T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6356694A (en) | 1994-10-11 |
| DE69419503D1 (de) | 1999-08-19 |
| DK0689422T3 (da) | 1999-12-06 |
| EP0689422B1 (de) | 1999-07-14 |
| US5635538A (en) | 1997-06-03 |
| ES2133546T3 (es) | 1999-09-16 |
| JPH08507786A (ja) | 1996-08-20 |
| EP0689422A1 (de) | 1996-01-03 |
| DE69419503T2 (de) | 1999-11-18 |
| AU679052B2 (en) | 1997-06-19 |
| WO1994021227A1 (en) | 1994-09-29 |
| GR3030793T3 (en) | 1999-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |