DE69409578D1 - Verfahren für die Synthese von 9-(2-Hydroxyethoxymethyl)guanin - Google Patents

Verfahren für die Synthese von 9-(2-Hydroxyethoxymethyl)guanin

Info

Publication number
DE69409578D1
DE69409578D1 DE69409578T DE69409578T DE69409578D1 DE 69409578 D1 DE69409578 D1 DE 69409578D1 DE 69409578 T DE69409578 T DE 69409578T DE 69409578 T DE69409578 T DE 69409578T DE 69409578 D1 DE69409578 D1 DE 69409578D1
Authority
DE
Germany
Prior art keywords
guanine
synthesis
hydroxyethoxymethyl
acyclovir
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69409578T
Other languages
English (en)
Other versions
DE69409578T2 (de
Inventor
Tiberio Bruzzese
Giuseppe Guazzi
Marco Rognoni
Giuliano Marcon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solchem Italiana SpA
Original Assignee
Solar Chemical SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solar Chemical SA filed Critical Solar Chemical SA
Publication of DE69409578D1 publication Critical patent/DE69409578D1/de
Application granted granted Critical
Publication of DE69409578T2 publication Critical patent/DE69409578T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69409578T 1993-06-14 1994-06-01 Verfahren für die Synthese von 9-(2-Hydroxyethoxymethyl)guanin Expired - Fee Related DE69409578T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001264A IT1264599B1 (it) 1993-06-14 1993-06-14 Processo per la sintesi della 9-(2-idrossietossimetil)- guanina

Publications (2)

Publication Number Publication Date
DE69409578D1 true DE69409578D1 (de) 1998-05-20
DE69409578T2 DE69409578T2 (de) 1998-11-19

Family

ID=11366388

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69409578T Expired - Fee Related DE69409578T2 (de) 1993-06-14 1994-06-01 Verfahren für die Synthese von 9-(2-Hydroxyethoxymethyl)guanin

Country Status (7)

Country Link
US (1) US5496945A (de)
EP (1) EP0628558B1 (de)
AT (1) ATE165096T1 (de)
DE (1) DE69409578T2 (de)
DK (1) DK0628558T3 (de)
ES (1) ES2117172T3 (de)
IT (1) IT1264599B1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1276126B1 (it) * 1995-11-14 1997-10-27 Archimica Spa Procedimento per la preparazine di 9-((2-idrossietossi)metil) guanina
CN103601768B (zh) * 2013-11-13 2015-09-30 齐鲁天和惠世制药有限公司 一种阿米卡星的制备方法
CN107903268A (zh) * 2017-11-16 2018-04-13 湖北省宏源药业科技股份有限公司 一种阿昔洛韦的提纯方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4146715A (en) * 1975-08-27 1979-03-27 Burroughs Wellcome Co. 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
DK135489D0 (da) * 1989-03-20 1989-03-20 Gea Farmaceutisk Fabrik As Fremgangsmaade til fremstilling af 9-substituerede guaninderivater og mellemprodukter til brug ved fremgangsmaaden
JP3225545B2 (ja) * 1991-09-18 2001-11-05 味の素株式会社 非環状ヌクレオシド類の製造法

Also Published As

Publication number Publication date
ES2117172T3 (es) 1998-08-01
ITMI931264A0 (it) 1993-06-14
IT1264599B1 (it) 1996-10-04
US5496945A (en) 1996-03-05
ITMI931264A1 (it) 1994-12-14
DE69409578T2 (de) 1998-11-19
EP0628558B1 (de) 1998-04-15
EP0628558A1 (de) 1994-12-14
ATE165096T1 (de) 1998-05-15
DK0628558T3 (da) 1999-02-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SOLCHEM ITALIANA S.P.A., MULAZZANO, IT

8339 Ceased/non-payment of the annual fee