DE69333782D1 - Ein proteinase inhibitor, vorläufer davon und genetische sequenzen dafür kodierend - Google Patents

Ein proteinase inhibitor, vorläufer davon und genetische sequenzen dafür kodierend

Info

Publication number
DE69333782D1
DE69333782D1 DE69333782T DE69333782T DE69333782D1 DE 69333782 D1 DE69333782 D1 DE 69333782D1 DE 69333782 T DE69333782 T DE 69333782T DE 69333782 T DE69333782 T DE 69333782T DE 69333782 D1 DE69333782 D1 DE 69333782D1
Authority
DE
Germany
Prior art keywords
genetic sequences
proteinase inhibitor
presenter
coding
monomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333782T
Other languages
English (en)
Other versions
DE69333782T2 (de
Inventor
Anne Anderson
Hilary Atkinson
Louise Heath
Elizabeth Clarke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexima Ltd
Original Assignee
Hexima Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hexima Ltd filed Critical Hexima Ltd
Publication of DE69333782D1 publication Critical patent/DE69333782D1/de
Application granted granted Critical
Publication of DE69333782T2 publication Critical patent/DE69333782T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/06—Uses of viruses as vector in vitro
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69333782T 1992-12-16 1993-12-16 Ein proteinase-inhibitor, vorläufer davon und dafür kodierende genetische sequenzen Expired - Lifetime DE69333782T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPL639992 1992-12-16
AUPL639992 1992-12-16
PCT/AU1993/000659 WO1994013810A1 (en) 1992-12-16 1993-12-16 A proteinase inhibitor, precursor thereof and genetic sequences encoding same

Publications (2)

Publication Number Publication Date
DE69333782D1 true DE69333782D1 (de) 2005-04-28
DE69333782T2 DE69333782T2 (de) 2006-01-26

Family

ID=3776602

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333782T Expired - Lifetime DE69333782T2 (de) 1992-12-16 1993-12-16 Ein proteinase-inhibitor, vorläufer davon und dafür kodierende genetische sequenzen

Country Status (9)

Country Link
US (10) US6031087A (de)
EP (1) EP0674712B1 (de)
JP (3) JP3657980B2 (de)
AT (1) ATE291624T1 (de)
CA (1) CA2151933C (de)
DE (1) DE69333782T2 (de)
ES (1) ES2239754T3 (de)
NZ (1) NZ258824A (de)
WO (1) WO1994013810A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013810A1 (en) * 1992-12-16 1994-06-23 The University Of Melbourne A proteinase inhibitor, precursor thereof and genetic sequences encoding same
US6121436A (en) 1996-12-13 2000-09-19 Monsanto Company Antifungal polypeptide and methods for controlling plant pathogenic fungi
GB9725556D0 (en) * 1997-12-03 1998-02-04 Ciba Geigy Ag Organic compounds
EP0958833A1 (de) * 1998-05-20 1999-11-24 Erasmus Universiteit Rotterdam Verfahren und Mittel zur Vorbeugung oder Behandlung der Entzündung
AU2002229407C1 (en) * 2001-02-08 2005-09-01 Hexima Limited Plant-derived molecules and genetic sequences encoding same and uses therefor
WO2004050873A1 (en) * 2002-11-29 2004-06-17 The University Of Hong Kong Genetically modified plants expressing proteinase inhibitors, sapina2a or sapin2b, and methods of use thereof for the inhibition of trypsin-and chymotrypsin-like activities
AU2004233354B2 (en) * 2003-04-23 2008-02-21 Hexima Limited Insect chymotrypsin and inhibitors thereof
US20060035827A1 (en) * 2004-06-24 2006-02-16 Green Gary M Compositions and methods for the treatment or prevention of gallbladder disease
CA2614353A1 (en) * 2005-07-08 2007-01-18 Hexima Limited Management of plant pathogens
WO2007137329A2 (en) * 2006-05-25 2007-12-06 Hexima Limited Multi-gene expression vehicle
CN101848938A (zh) 2007-04-20 2010-09-29 赫希玛有限公司 经修饰的植物防卫素
AR075257A1 (es) * 2008-02-01 2011-03-23 Hexima Ltd Sistema de proteccion de plantas contra la infeccion por agentes patogenos
CA2733267A1 (en) * 2008-08-05 2010-02-11 Hexima Limited Plant anti-pathogen systems
US9889184B2 (en) 2008-08-05 2018-02-13 Hexima Limited Anti-pathogen systems
US9497908B2 (en) 2011-02-07 2016-11-22 Hexima Limited Modified plant defensins useful as anti-pathogenic agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI875467A (fi) * 1986-12-19 1988-06-20 Agricultural Genetics Co Dna-molekyler, som aer nyttiga vid vaextskydd.
JPS6413997U (de) 1987-07-17 1989-01-24
JPS6453092A (en) 1987-08-21 1989-03-01 Hitachi Ltd Blower device
US5032396A (en) * 1989-02-17 1991-07-16 Immunex Corporation IL-7 to stimulate platelet production
DE59010422D1 (de) * 1989-12-22 1996-08-22 Mikrogen Molekularbiol Entw Immunologisch aktive proteine von borrelia burgdorferi, zusammenhängende testkits und impfstoff
ATE142420T1 (de) 1990-05-25 1996-09-15 Univ Washington Verfahren zur auslösung pflanzenschützender mechanismen
JPH04145099A (ja) * 1990-10-05 1992-05-19 Sanwa Kagaku Kenkyusho Co Ltd Ｇｉｐ様活性を有するポリペプチド誘導体及びその用途
GB9104617D0 (en) * 1991-03-05 1991-04-17 Nickerson Int Seed Pest control
WO1994013810A1 (en) * 1992-12-16 1994-06-23 The University Of Melbourne A proteinase inhibitor, precursor thereof and genetic sequences encoding same

Also Published As

Publication number Publication date
EP0674712A4 (de) 1997-06-18
EP0674712A1 (de) 1995-10-04
US6806074B2 (en) 2004-10-19
WO1994013810A1 (en) 1994-06-23
NZ258824A (en) 1997-11-24
US7410796B2 (en) 2008-08-12
US20050250149A1 (en) 2005-11-10
JPH11346788A (ja) 1999-12-21
US6451573B1 (en) 2002-09-17
ATE291624T1 (de) 2005-04-15
ES2239754T3 (es) 2005-10-01
US6261821B1 (en) 2001-07-17
US6031087A (en) 2000-02-29
US20030027303A1 (en) 2003-02-06
CA2151933A1 (en) 1994-06-23
JP4115642B2 (ja) 2008-07-09
DE69333782T2 (de) 2006-01-26
US6946278B2 (en) 2005-09-20
US20070054365A1 (en) 2007-03-08
CA2151933C (en) 2007-04-24
JP2000175581A (ja) 2000-06-27
US6440727B1 (en) 2002-08-27
US20030096388A1 (en) 2003-05-22
US6955916B2 (en) 2005-10-18
JP3657980B2 (ja) 2005-06-08
JPH08506482A (ja) 1996-07-16
US20080134367A1 (en) 2008-06-05
EP0674712B1 (de) 2005-03-23
US20030129720A1 (en) 2003-07-10
US7309596B2 (en) 2007-12-18

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Legal Events

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