DE69333547D1 - Therapeutische anwendungen von chimänischer organogenese - Google Patents

Therapeutische anwendungen von chimänischer organogenese

Info

Publication number
DE69333547D1
DE69333547D1 DE69333547T DE69333547T DE69333547D1 DE 69333547 D1 DE69333547 D1 DE 69333547D1 DE 69333547 T DE69333547 T DE 69333547T DE 69333547 T DE69333547 T DE 69333547T DE 69333547 D1 DE69333547 D1 DE 69333547D1
Authority
DE
Germany
Prior art keywords
cells
chimeric
autologous
epithelium
allogeneic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69333547T
Other languages
English (en)
Other versions
DE69333547T2 (de
Inventor
F A Auger
M Rouabhia
L Lafleur
L Germain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Laval
Original Assignee
Universite Laval
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Laval filed Critical Universite Laval
Application granted granted Critical
Publication of DE69333547D1 publication Critical patent/DE69333547D1/de
Publication of DE69333547T2 publication Critical patent/DE69333547T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60—Materials for use in artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • C12N5/0629—Keratinocytes; Whole skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/16—Magnesium; Mg chelators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915—Method or apparatus for preparing biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE69333547T 1993-01-21 1993-12-21 Therapeutische anwendungen von chimänischer organogenese Expired - Lifetime DE69333547T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7318 1993-01-21
US08/007,318 US5610007A (en) 1993-01-21 1993-01-21 Chimeric sheets of epithelial cells
PCT/CA1993/000546 WO1994017179A1 (en) 1993-01-21 1993-12-21 Therapeutic applications of chimeric organogenesis

Publications (2)

Publication Number Publication Date
DE69333547D1 true DE69333547D1 (de) 2004-07-15
DE69333547T2 DE69333547T2 (de) 2005-08-18

Family

ID=21725473

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333547T Expired - Lifetime DE69333547T2 (de) 1993-01-21 1993-12-21 Therapeutische anwendungen von chimänischer organogenese

Country Status (7)

Country Link
US (1) US5610007A (de)
EP (1) EP0681608B1 (de)
JP (1) JP3748882B2 (de)
AT (1) ATE268811T1 (de)
DE (1) DE69333547T2 (de)
NZ (1) NZ258838A (de)
WO (1) WO1994017179A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002504412A (ja) * 1998-02-24 2002-02-12 アドバンスト ティシュー サイエンス インコポレイテッド 生きたキメラ皮膚置換体
US6964869B2 (en) * 1998-07-13 2005-11-15 Wisconsin Alumni Research Foundation Method and composition for skin grafts
US20060030044A1 (en) * 1998-07-13 2006-02-09 Allen-Hoffmann B Lynn Method and composition for skin grafts
EP1263931A4 (de) * 1999-11-05 2009-07-15 Gerigene Medical Corp Verstärkung und reparatur von altersbedingten schwächen des weichteilgewebes
US20020039788A1 (en) * 2000-02-29 2002-04-04 Isseroff Roslyn R. Corneal epithelial graft composites
EP1390754B1 (de) * 2001-04-24 2007-08-01 Wisconsin Alumni Research Foundation Verfahren und zusammensetzung für hauttransplantate
US20050170501A1 (en) * 2002-04-24 2005-08-04 Auger Francois A. Method for preparing tissue constructs
TW558677B (en) * 2002-08-02 2003-10-21 Chih-Hao Yiu Device for detecting angular position
EP1782846A1 (de) * 2004-06-30 2007-05-09 Arblast Co., Ltd. Hornhautepithelplatte und verfahren zu ihrer herstellung
CN101912636B (zh) * 2010-05-19 2014-03-19 郭爱华 迷你皮肤结构及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769317A (en) * 1983-06-14 1988-09-06 Hefton John M Process for growing human epidermis, product thereof
FR2589165B1 (fr) * 1985-10-24 1989-01-20 Inst Nat Sante Rech Med Procede d'obtention d'un epithelium humain de culture, tissu epithelial obtenu et son application aux allogreffes
US5032508A (en) * 1988-09-08 1991-07-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
CA2000181A1 (en) * 1988-10-14 1990-04-14 Chung-Faye Chao Process for producing cultured epidermal sheet, product and method of use
IL94611A (en) * 1989-06-05 1994-12-29 Organogenesis Inc Medium for cell cultures containing insulin or growth factor similar to insulin, transferrin or iron ion, triiodothyronine or thyroxine and method of use
EP0950707B1 (de) * 1989-07-25 2009-02-18 Cell Genesys, Inc. Homologe Rekombination für universelle Donorzellen und chimerische Säugetierzellen
ES2111566T3 (es) * 1990-04-24 1998-03-16 Mark Eisenberg Equivalentes compuestos de piel viva.

Also Published As

Publication number Publication date
WO1994017179A1 (en) 1994-08-04
US5610007A (en) 1997-03-11
DE69333547T2 (de) 2005-08-18
ATE268811T1 (de) 2004-06-15
JP3748882B2 (ja) 2006-02-22
AU5690594A (en) 1994-08-15
EP0681608B1 (de) 2004-06-09
AU682485B2 (en) 1997-10-09
NZ258838A (en) 1998-03-25
EP0681608A1 (de) 1995-11-15
JPH08508876A (ja) 1996-09-24

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Legal Events

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