DE69332365T2 - Vorrichtung zur Messung von Fluoreszenz - Google Patents

Vorrichtung zur Messung von Fluoreszenz

Info

Publication number
DE69332365T2
DE69332365T2 DE69332365T DE69332365T DE69332365T2 DE 69332365 T2 DE69332365 T2 DE 69332365T2 DE 69332365 T DE69332365 T DE 69332365T DE 69332365 T DE69332365 T DE 69332365T DE 69332365 T2 DE69332365 T2 DE 69332365T2
Authority
DE
Germany
Prior art keywords
measuring fluorescence
fluorescence
measuring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69332365T
Other languages
English (en)
Other versions
DE69332365D1 (de
Inventor
Yasutami Mitoma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tosoh Corp
Original Assignee
Tosoh Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tosoh Corp filed Critical Tosoh Corp
Application granted granted Critical
Publication of DE69332365D1 publication Critical patent/DE69332365D1/de
Publication of DE69332365T2 publication Critical patent/DE69332365T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0367Supports of cells, e.g. pivotable
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0367Supports of cells, e.g. pivotable
    • G01N2021/0371Supports combined with sample intake
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6484Optical fibres
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/028Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/808Optical sensing apparatus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE69332365T 1992-07-17 1993-07-15 Vorrichtung zur Messung von Fluoreszenz Expired - Fee Related DE69332365T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4212288A JPH0634546A (ja) 1992-07-17 1992-07-17 蛍光検出器

Publications (2)

Publication Number Publication Date
DE69332365D1 DE69332365D1 (de) 2002-11-14
DE69332365T2 true DE69332365T2 (de) 2003-02-13

Family

ID=16620119

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332365T Expired - Fee Related DE69332365T2 (de) 1992-07-17 1993-07-15 Vorrichtung zur Messung von Fluoreszenz

Country Status (4)

Country Link
US (1) US6144448A (de)
EP (1) EP0580362B1 (de)
JP (1) JPH0634546A (de)
DE (1) DE69332365T2 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935522A (en) * 1990-06-04 1999-08-10 University Of Utah Research Foundation On-line DNA analysis system with rapid thermal cycling
US7081226B1 (en) 1996-06-04 2006-07-25 University Of Utah Research Foundation System and method for fluorescence monitoring
US7273749B1 (en) 1990-06-04 2007-09-25 University Of Utah Research Foundation Container for carrying out and monitoring biological processes
US5994056A (en) 1991-05-02 1999-11-30 Roche Molecular Systems, Inc. Homogeneous methods for nucleic acid amplification and detection
US6063633A (en) * 1996-02-28 2000-05-16 The University Of Houston Catalyst testing process and apparatus
US5935524A (en) * 1996-05-07 1999-08-10 E. I. Du Pont De Nemours And Company Holder for fluorometric samples
JP4281877B2 (ja) * 1996-06-04 2009-06-17 ユニバーシティ オブ ユタ リサーチ ファウンデーション 生物学的プロセスを実行し且つモニタリングするためのシステムと方法
ATE295427T1 (de) 1996-06-04 2005-05-15 Univ Utah Res Found Überwachung der hybridisierung während pcr
JPH1048123A (ja) * 1996-08-06 1998-02-20 Kubota Corp 分光分析装置
JP2835034B2 (ja) * 1996-10-21 1998-12-14 松下電工株式会社 遠隔監視制御システムのインターフェース端末器
US8293064B2 (en) * 1998-03-02 2012-10-23 Cepheid Method for fabricating a reaction vessel
DK2308995T3 (da) 1997-02-28 2015-08-03 Cepheid Kemisk reaktionsenhed med varmeveksler og optisk detektor
US6369893B1 (en) 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6660228B1 (en) 1998-03-02 2003-12-09 Cepheid Apparatus for performing heat-exchanging, chemical reactions
DE69825142T2 (de) * 1998-05-01 2005-08-11 F. Hoffmann-La Roche Ag Vorrichtung zur gleichzeitigen Überwachung von Reaktionen, die in einer Vielzahl von Reaktionsgefässen stattfinden
EP1950553B1 (de) * 1999-08-20 2016-02-24 Nanodrop Technologies LLC Fotometer zum Vermessen einer mittels Oberflächenspannung gehaltenen flüssigen Probe
EP1080785A1 (de) * 1999-09-04 2001-03-07 F. Hoffmann-La Roche Ag Thermozyklisches System für Fluide in Patronen
WO2001021302A1 (en) * 1999-09-20 2001-03-29 General Electric Company Method and apparatus for conducting melt-polymerization reactions
US6605813B1 (en) * 1999-10-09 2003-08-12 Bhk, Inc. Benchtop fluorescence molecular beacons detector and reader
US6403037B1 (en) * 2000-02-04 2002-06-11 Cepheid Reaction vessel and temperature control system
JP4569030B2 (ja) 2001-04-23 2010-10-27 東ソー株式会社 外部光下で計測可能な蛍光検出方法、および装置
WO2003002959A1 (en) * 2001-06-15 2003-01-09 Mj Research, Inc. Controller for a fluorometer
US6839375B1 (en) * 2001-09-06 2005-01-04 Lambda Physik Ag On-line quality control of the key optical components in lithography lasers using laser induced fluorescence
US6970492B2 (en) * 2002-05-17 2005-11-29 Lambda Physik Ag DUV and VUV laser with on-line pulse energy monitor
GB0221167D0 (en) * 2002-09-12 2002-10-23 Quanta Biotech Ltd Control apparatus
US7148043B2 (en) 2003-05-08 2006-12-12 Bio-Rad Laboratories, Inc. Systems and methods for fluorescence detection with a movable detection module
US7795034B2 (en) * 2003-07-03 2010-09-14 Wako Pure Chemical Industries, Ltd. Specific component measuring method by spectral measurement
DE102004056787A1 (de) * 2004-11-24 2006-06-01 Heinrich-Heine-Universität Düsseldorf Vorrichtung und Verfahren zur Messung von Fluoreszenz in mehreren Reaktionsräumen
US20060133080A1 (en) * 2004-12-17 2006-06-22 Bio-Rad Laboratories, Inc., A Corporation Of The State Of Delaware Multiple light source orientation system for multi-well reaction plate
US7507575B2 (en) * 2005-04-01 2009-03-24 3M Innovative Properties Company Multiplex fluorescence detection device having removable optical modules
US7709249B2 (en) * 2005-04-01 2010-05-04 3M Innovative Properties Company Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector
CN101156059B (zh) * 2005-04-01 2011-06-08 3M创新有限公司 具有将多个光学模块连接到公共检测器的纤维束的多重荧光检测装置
US20070009382A1 (en) * 2005-07-05 2007-01-11 William Bedingham Heating element for a rotating multiplex fluorescence detection device
US7527763B2 (en) * 2005-07-05 2009-05-05 3M Innovative Properties Company Valve control system for a rotating multiplex fluorescence detection device
US7569382B2 (en) * 2005-10-05 2009-08-04 Instantlabs Medical Diagnostic Corp. Disposable reactor module and detection system
JP2007163403A (ja) * 2005-12-16 2007-06-28 Fujifilm Corp 試料液容器
US8551408B2 (en) * 2006-01-24 2013-10-08 Life Technologies Corporation Device and methods for quantifying analytes
US8232091B2 (en) * 2006-05-17 2012-07-31 California Institute Of Technology Thermal cycling system
EP2425894B1 (de) 2007-06-21 2016-12-28 Gen-Probe Incorporated Instrumente und Verfahren zur Aussetzung eines Behälters zu mehreren Wärmezonen
WO2009103003A2 (en) * 2008-02-15 2009-08-20 Bio-Rad Laboratories, Inc. Scanning fluorescent reader with diffuser system
KR20110008261A (ko) * 2008-04-24 2011-01-26 쓰리엠 이노베이티브 프로퍼티즈 컴파니 웨이블릿 변환을 사용한 핵산 증폭 곡선의 분석
US8134694B2 (en) * 2008-05-09 2012-03-13 Apollo Diamond Gemstone Corporation Detection of chemical vapor deposition grown diamond
US8213000B2 (en) * 2008-05-09 2012-07-03 Apollo Diamond Gemstone Corporation Retail compatible detection of CVD grown diamond
EP2376896B1 (de) * 2009-01-08 2021-05-19 IT-IS International Ltd Optisches system für chemische und/oder biochemische reaktionen
CN201837588U (zh) 2009-09-09 2011-05-18 海利克斯公司 用于多个反应的光学系统
DE102010010741A1 (de) * 2010-03-09 2011-09-15 Beckman Coulter, Inc. Lichtleitervorrichtung zum Abstrahlen und Empfangen von Licht, System, Verfahren und Computerprogrammprodukt
JP5669087B2 (ja) 2010-09-28 2015-02-12 国立大学法人九州工業大学 蛍光測定方法及び蛍光測定装置
JP2012093190A (ja) * 2010-10-26 2012-05-17 Olympus Corp 蛍光センサの補正方法おび蛍光センサ
EP2463661B1 (de) 2010-11-15 2014-01-08 F. Hoffmann-La Roche AG Instrument und Verfahren zur automatisierten Wärmebehandlung von Flüssigkeitsproben
IT1403792B1 (it) * 2010-12-30 2013-10-31 St Microelectronics Srl Analizzatore per analisi biochimiche e metodo per la determinazione di concentrazioni di sostanze fluorescenti in una soluzione
US9096892B1 (en) * 2011-02-04 2015-08-04 K2 Biomicrosystems, LLC Nucleic acid amplification and monitoring apparatus
EP2525211B1 (de) 2011-05-16 2018-01-03 F. Hoffmann-La Roche AG Instrument und verfahren zum detektieren von analyten
US9121827B2 (en) 2011-06-30 2015-09-01 Mocon, Inc. Method of contemporaneously monitoring changes in analyte concentration in a plurality of samples on individual schedules
JP5619690B2 (ja) * 2011-07-26 2014-11-05 株式会社古河電工アドバンストエンジニアリング 蛍光測定装置、ウェルの製造方法
JPWO2013140617A1 (ja) * 2012-03-23 2015-08-03 株式会社島津製作所 検出器及びその検出器を備えた液体クロマトグラフ
AU2014277774C1 (en) * 2012-07-31 2019-09-19 Gen-Probe Incorporated System, Method and Apparatus for Automated Incubation
AU2013202793B2 (en) * 2012-07-31 2014-09-18 Gen-Probe Incorporated System, method and apparatus for automated incubation
US9932632B2 (en) 2012-08-10 2018-04-03 Streck, Inc. Real-time optical system for polymerase chain reaction
EP2893320B1 (de) * 2012-08-20 2020-12-23 Siemens Healthcare Diagnostics Inc. Zweischaliges luminometer
EP3699592A1 (de) 2013-03-13 2020-08-26 Geneweave Biosciences Inc. Nichtreplikative transduktionspartikel und auf transduktionspartikeln basierende reportersysteme
US9481903B2 (en) * 2013-03-13 2016-11-01 Roche Molecular Systems, Inc. Systems and methods for detection of cells using engineered transduction particles
AU2013202805B2 (en) 2013-03-14 2015-07-16 Gen-Probe Incorporated System and method for extending the capabilities of a diagnostic analyzer
EP3014251A1 (de) 2013-06-28 2016-05-04 Streck Inc. Vorrichtungen für echtzeit-polymerasekettenreaktionen
US9540675B2 (en) 2013-10-29 2017-01-10 GeneWeave Biosciences, Inc. Reagent cartridge and methods for detection of cells
US10351893B2 (en) 2015-10-05 2019-07-16 GeneWeave Biosciences, Inc. Reagent cartridge for detection of cells
CN106635785B (zh) * 2016-12-29 2019-04-19 湖南圣湘生物科技有限公司 一种pcr荧光检测仪
US11077444B2 (en) 2017-05-23 2021-08-03 Roche Molecular Systems, Inc. Packaging for a molecular diagnostic cartridge
DE102017223851B4 (de) * 2017-12-28 2020-08-06 Biochip Systems GmbH Sensoranordnung zur Detektion wenigstens einer stofflichen Eigenschaft einer Probe sowie Mikrotiter-Platte mit einer Vielzahl von Sensoranordnungen
CN108456640A (zh) * 2018-05-24 2018-08-28 南京岚煜生物科技有限公司 用于全自动核酸提取扩增诊断一体机的pcr模块

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3992631A (en) * 1975-02-27 1976-11-16 International Diagnostic Technology, Inc. Fluorometric system, method and test article
JPS57132038A (en) * 1981-02-10 1982-08-16 Olympus Optical Co Ltd Photometric device
JPS59178337A (ja) * 1983-03-29 1984-10-09 Toshiba Corp 自動化学分析装置
FI831936A0 (fi) * 1983-05-30 1983-05-30 Labsystems Oy Anordning foer maetning av fluorescens, turbiditet, luminescens eller absorption
DE3410957A1 (de) * 1984-03-24 1985-09-26 Henkel KGaA, 4000 Düsseldorf Waessrige trennmittel
US4801187A (en) * 1986-04-30 1989-01-31 Baxter Travenol Laboratories, Inc. Liquid light tube end cap assembly
EP0266881A3 (de) * 1986-09-30 1990-04-04 Astromed Limited Verfahren und Vorrichtung für optische Mehrfachprüfung
US5217876A (en) * 1988-03-15 1993-06-08 Akzo N.V. Method for detecting microorganisms
US5252834A (en) * 1990-11-13 1993-10-12 Union Oil Company Of California Pulsed and gated multi-mode microspectrophotometry device and method
JPH04348258A (ja) * 1991-05-27 1992-12-03 Kowa Co 多チャンネル光学測定装置
CA2100020C (en) * 1992-07-17 2001-09-11 Walter Blumenfeld Methods and apparatus for detecting bacterial growth by spectrophotometric sampling of a fiber-optic array
US5371016A (en) * 1993-04-26 1994-12-06 Becton, Dickinson And Company Detecting biological activities in culture vials

Also Published As

Publication number Publication date
JPH0634546A (ja) 1994-02-08
EP0580362B1 (de) 2002-10-09
EP0580362A1 (de) 1994-01-26
US6144448A (en) 2000-11-07
DE69332365D1 (de) 2002-11-14

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee