DE69332365T2 - Vorrichtung zur Messung von Fluoreszenz - Google Patents
Vorrichtung zur Messung von FluoreszenzInfo
- Publication number
- DE69332365T2 DE69332365T2 DE69332365T DE69332365T DE69332365T2 DE 69332365 T2 DE69332365 T2 DE 69332365T2 DE 69332365 T DE69332365 T DE 69332365T DE 69332365 T DE69332365 T DE 69332365T DE 69332365 T2 DE69332365 T2 DE 69332365T2
- Authority
- DE
- Germany
- Prior art keywords
- measuring fluorescence
- fluorescence
- measuring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0367—Supports of cells, e.g. pivotable
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0367—Supports of cells, e.g. pivotable
- G01N2021/0371—Supports combined with sample intake
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6484—Optical fibres
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4212288A JPH0634546A (ja) | 1992-07-17 | 1992-07-17 | 蛍光検出器 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69332365D1 DE69332365D1 (de) | 2002-11-14 |
DE69332365T2 true DE69332365T2 (de) | 2003-02-13 |
Family
ID=16620119
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69332365T Expired - Fee Related DE69332365T2 (de) | 1992-07-17 | 1993-07-15 | Vorrichtung zur Messung von Fluoreszenz |
Country Status (4)
Country | Link |
---|---|
US (1) | US6144448A (de) |
EP (1) | EP0580362B1 (de) |
JP (1) | JPH0634546A (de) |
DE (1) | DE69332365T2 (de) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5935522A (en) * | 1990-06-04 | 1999-08-10 | University Of Utah Research Foundation | On-line DNA analysis system with rapid thermal cycling |
US7081226B1 (en) | 1996-06-04 | 2006-07-25 | University Of Utah Research Foundation | System and method for fluorescence monitoring |
US7273749B1 (en) | 1990-06-04 | 2007-09-25 | University Of Utah Research Foundation | Container for carrying out and monitoring biological processes |
US5994056A (en) | 1991-05-02 | 1999-11-30 | Roche Molecular Systems, Inc. | Homogeneous methods for nucleic acid amplification and detection |
US6063633A (en) * | 1996-02-28 | 2000-05-16 | The University Of Houston | Catalyst testing process and apparatus |
US5935524A (en) * | 1996-05-07 | 1999-08-10 | E. I. Du Pont De Nemours And Company | Holder for fluorometric samples |
JP4281877B2 (ja) * | 1996-06-04 | 2009-06-17 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | 生物学的プロセスを実行し且つモニタリングするためのシステムと方法 |
ATE295427T1 (de) | 1996-06-04 | 2005-05-15 | Univ Utah Res Found | Überwachung der hybridisierung während pcr |
JPH1048123A (ja) * | 1996-08-06 | 1998-02-20 | Kubota Corp | 分光分析装置 |
JP2835034B2 (ja) * | 1996-10-21 | 1998-12-14 | 松下電工株式会社 | 遠隔監視制御システムのインターフェース端末器 |
US8293064B2 (en) * | 1998-03-02 | 2012-10-23 | Cepheid | Method for fabricating a reaction vessel |
DK2308995T3 (da) | 1997-02-28 | 2015-08-03 | Cepheid | Kemisk reaktionsenhed med varmeveksler og optisk detektor |
US6369893B1 (en) | 1998-05-19 | 2002-04-09 | Cepheid | Multi-channel optical detection system |
US6660228B1 (en) | 1998-03-02 | 2003-12-09 | Cepheid | Apparatus for performing heat-exchanging, chemical reactions |
DE69825142T2 (de) * | 1998-05-01 | 2005-08-11 | F. Hoffmann-La Roche Ag | Vorrichtung zur gleichzeitigen Überwachung von Reaktionen, die in einer Vielzahl von Reaktionsgefässen stattfinden |
EP1950553B1 (de) * | 1999-08-20 | 2016-02-24 | Nanodrop Technologies LLC | Fotometer zum Vermessen einer mittels Oberflächenspannung gehaltenen flüssigen Probe |
EP1080785A1 (de) * | 1999-09-04 | 2001-03-07 | F. Hoffmann-La Roche Ag | Thermozyklisches System für Fluide in Patronen |
WO2001021302A1 (en) * | 1999-09-20 | 2001-03-29 | General Electric Company | Method and apparatus for conducting melt-polymerization reactions |
US6605813B1 (en) * | 1999-10-09 | 2003-08-12 | Bhk, Inc. | Benchtop fluorescence molecular beacons detector and reader |
US6403037B1 (en) * | 2000-02-04 | 2002-06-11 | Cepheid | Reaction vessel and temperature control system |
JP4569030B2 (ja) | 2001-04-23 | 2010-10-27 | 東ソー株式会社 | 外部光下で計測可能な蛍光検出方法、および装置 |
WO2003002959A1 (en) * | 2001-06-15 | 2003-01-09 | Mj Research, Inc. | Controller for a fluorometer |
US6839375B1 (en) * | 2001-09-06 | 2005-01-04 | Lambda Physik Ag | On-line quality control of the key optical components in lithography lasers using laser induced fluorescence |
US6970492B2 (en) * | 2002-05-17 | 2005-11-29 | Lambda Physik Ag | DUV and VUV laser with on-line pulse energy monitor |
GB0221167D0 (en) * | 2002-09-12 | 2002-10-23 | Quanta Biotech Ltd | Control apparatus |
US7148043B2 (en) | 2003-05-08 | 2006-12-12 | Bio-Rad Laboratories, Inc. | Systems and methods for fluorescence detection with a movable detection module |
US7795034B2 (en) * | 2003-07-03 | 2010-09-14 | Wako Pure Chemical Industries, Ltd. | Specific component measuring method by spectral measurement |
DE102004056787A1 (de) * | 2004-11-24 | 2006-06-01 | Heinrich-Heine-Universität Düsseldorf | Vorrichtung und Verfahren zur Messung von Fluoreszenz in mehreren Reaktionsräumen |
US20060133080A1 (en) * | 2004-12-17 | 2006-06-22 | Bio-Rad Laboratories, Inc., A Corporation Of The State Of Delaware | Multiple light source orientation system for multi-well reaction plate |
US7507575B2 (en) * | 2005-04-01 | 2009-03-24 | 3M Innovative Properties Company | Multiplex fluorescence detection device having removable optical modules |
US7709249B2 (en) * | 2005-04-01 | 2010-05-04 | 3M Innovative Properties Company | Multiplex fluorescence detection device having fiber bundle coupling multiple optical modules to a common detector |
CN101156059B (zh) * | 2005-04-01 | 2011-06-08 | 3M创新有限公司 | 具有将多个光学模块连接到公共检测器的纤维束的多重荧光检测装置 |
US20070009382A1 (en) * | 2005-07-05 | 2007-01-11 | William Bedingham | Heating element for a rotating multiplex fluorescence detection device |
US7527763B2 (en) * | 2005-07-05 | 2009-05-05 | 3M Innovative Properties Company | Valve control system for a rotating multiplex fluorescence detection device |
US7569382B2 (en) * | 2005-10-05 | 2009-08-04 | Instantlabs Medical Diagnostic Corp. | Disposable reactor module and detection system |
JP2007163403A (ja) * | 2005-12-16 | 2007-06-28 | Fujifilm Corp | 試料液容器 |
US8551408B2 (en) * | 2006-01-24 | 2013-10-08 | Life Technologies Corporation | Device and methods for quantifying analytes |
US8232091B2 (en) * | 2006-05-17 | 2012-07-31 | California Institute Of Technology | Thermal cycling system |
EP2425894B1 (de) | 2007-06-21 | 2016-12-28 | Gen-Probe Incorporated | Instrumente und Verfahren zur Aussetzung eines Behälters zu mehreren Wärmezonen |
WO2009103003A2 (en) * | 2008-02-15 | 2009-08-20 | Bio-Rad Laboratories, Inc. | Scanning fluorescent reader with diffuser system |
KR20110008261A (ko) * | 2008-04-24 | 2011-01-26 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 웨이블릿 변환을 사용한 핵산 증폭 곡선의 분석 |
US8134694B2 (en) * | 2008-05-09 | 2012-03-13 | Apollo Diamond Gemstone Corporation | Detection of chemical vapor deposition grown diamond |
US8213000B2 (en) * | 2008-05-09 | 2012-07-03 | Apollo Diamond Gemstone Corporation | Retail compatible detection of CVD grown diamond |
EP2376896B1 (de) * | 2009-01-08 | 2021-05-19 | IT-IS International Ltd | Optisches system für chemische und/oder biochemische reaktionen |
CN201837588U (zh) | 2009-09-09 | 2011-05-18 | 海利克斯公司 | 用于多个反应的光学系统 |
DE102010010741A1 (de) * | 2010-03-09 | 2011-09-15 | Beckman Coulter, Inc. | Lichtleitervorrichtung zum Abstrahlen und Empfangen von Licht, System, Verfahren und Computerprogrammprodukt |
JP5669087B2 (ja) | 2010-09-28 | 2015-02-12 | 国立大学法人九州工業大学 | 蛍光測定方法及び蛍光測定装置 |
JP2012093190A (ja) * | 2010-10-26 | 2012-05-17 | Olympus Corp | 蛍光センサの補正方法おび蛍光センサ |
EP2463661B1 (de) | 2010-11-15 | 2014-01-08 | F. Hoffmann-La Roche AG | Instrument und Verfahren zur automatisierten Wärmebehandlung von Flüssigkeitsproben |
IT1403792B1 (it) * | 2010-12-30 | 2013-10-31 | St Microelectronics Srl | Analizzatore per analisi biochimiche e metodo per la determinazione di concentrazioni di sostanze fluorescenti in una soluzione |
US9096892B1 (en) * | 2011-02-04 | 2015-08-04 | K2 Biomicrosystems, LLC | Nucleic acid amplification and monitoring apparatus |
EP2525211B1 (de) | 2011-05-16 | 2018-01-03 | F. Hoffmann-La Roche AG | Instrument und verfahren zum detektieren von analyten |
US9121827B2 (en) | 2011-06-30 | 2015-09-01 | Mocon, Inc. | Method of contemporaneously monitoring changes in analyte concentration in a plurality of samples on individual schedules |
JP5619690B2 (ja) * | 2011-07-26 | 2014-11-05 | 株式会社古河電工アドバンストエンジニアリング | 蛍光測定装置、ウェルの製造方法 |
JPWO2013140617A1 (ja) * | 2012-03-23 | 2015-08-03 | 株式会社島津製作所 | 検出器及びその検出器を備えた液体クロマトグラフ |
AU2014277774C1 (en) * | 2012-07-31 | 2019-09-19 | Gen-Probe Incorporated | System, Method and Apparatus for Automated Incubation |
AU2013202793B2 (en) * | 2012-07-31 | 2014-09-18 | Gen-Probe Incorporated | System, method and apparatus for automated incubation |
US9932632B2 (en) | 2012-08-10 | 2018-04-03 | Streck, Inc. | Real-time optical system for polymerase chain reaction |
EP2893320B1 (de) * | 2012-08-20 | 2020-12-23 | Siemens Healthcare Diagnostics Inc. | Zweischaliges luminometer |
EP3699592A1 (de) | 2013-03-13 | 2020-08-26 | Geneweave Biosciences Inc. | Nichtreplikative transduktionspartikel und auf transduktionspartikeln basierende reportersysteme |
US9481903B2 (en) * | 2013-03-13 | 2016-11-01 | Roche Molecular Systems, Inc. | Systems and methods for detection of cells using engineered transduction particles |
AU2013202805B2 (en) | 2013-03-14 | 2015-07-16 | Gen-Probe Incorporated | System and method for extending the capabilities of a diagnostic analyzer |
EP3014251A1 (de) | 2013-06-28 | 2016-05-04 | Streck Inc. | Vorrichtungen für echtzeit-polymerasekettenreaktionen |
US9540675B2 (en) | 2013-10-29 | 2017-01-10 | GeneWeave Biosciences, Inc. | Reagent cartridge and methods for detection of cells |
US10351893B2 (en) | 2015-10-05 | 2019-07-16 | GeneWeave Biosciences, Inc. | Reagent cartridge for detection of cells |
CN106635785B (zh) * | 2016-12-29 | 2019-04-19 | 湖南圣湘生物科技有限公司 | 一种pcr荧光检测仪 |
US11077444B2 (en) | 2017-05-23 | 2021-08-03 | Roche Molecular Systems, Inc. | Packaging for a molecular diagnostic cartridge |
DE102017223851B4 (de) * | 2017-12-28 | 2020-08-06 | Biochip Systems GmbH | Sensoranordnung zur Detektion wenigstens einer stofflichen Eigenschaft einer Probe sowie Mikrotiter-Platte mit einer Vielzahl von Sensoranordnungen |
CN108456640A (zh) * | 2018-05-24 | 2018-08-28 | 南京岚煜生物科技有限公司 | 用于全自动核酸提取扩增诊断一体机的pcr模块 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3992631A (en) * | 1975-02-27 | 1976-11-16 | International Diagnostic Technology, Inc. | Fluorometric system, method and test article |
JPS57132038A (en) * | 1981-02-10 | 1982-08-16 | Olympus Optical Co Ltd | Photometric device |
JPS59178337A (ja) * | 1983-03-29 | 1984-10-09 | Toshiba Corp | 自動化学分析装置 |
FI831936A0 (fi) * | 1983-05-30 | 1983-05-30 | Labsystems Oy | Anordning foer maetning av fluorescens, turbiditet, luminescens eller absorption |
DE3410957A1 (de) * | 1984-03-24 | 1985-09-26 | Henkel KGaA, 4000 Düsseldorf | Waessrige trennmittel |
US4801187A (en) * | 1986-04-30 | 1989-01-31 | Baxter Travenol Laboratories, Inc. | Liquid light tube end cap assembly |
EP0266881A3 (de) * | 1986-09-30 | 1990-04-04 | Astromed Limited | Verfahren und Vorrichtung für optische Mehrfachprüfung |
US5217876A (en) * | 1988-03-15 | 1993-06-08 | Akzo N.V. | Method for detecting microorganisms |
US5252834A (en) * | 1990-11-13 | 1993-10-12 | Union Oil Company Of California | Pulsed and gated multi-mode microspectrophotometry device and method |
JPH04348258A (ja) * | 1991-05-27 | 1992-12-03 | Kowa Co | 多チャンネル光学測定装置 |
CA2100020C (en) * | 1992-07-17 | 2001-09-11 | Walter Blumenfeld | Methods and apparatus for detecting bacterial growth by spectrophotometric sampling of a fiber-optic array |
US5371016A (en) * | 1993-04-26 | 1994-12-06 | Becton, Dickinson And Company | Detecting biological activities in culture vials |
-
1992
- 1992-07-17 JP JP4212288A patent/JPH0634546A/ja active Pending
-
1993
- 1993-07-15 DE DE69332365T patent/DE69332365T2/de not_active Expired - Fee Related
- 1993-07-15 EP EP93305569A patent/EP0580362B1/de not_active Expired - Lifetime
-
1996
- 1996-10-30 US US09/517,666 patent/US6144448A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0634546A (ja) | 1994-02-08 |
EP0580362B1 (de) | 2002-10-09 |
EP0580362A1 (de) | 1994-01-26 |
US6144448A (en) | 2000-11-07 |
DE69332365D1 (de) | 2002-11-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |