DE69331619D1 - Kapillardetektorzelle mit abbildenden Elementen zur Optimierung der Empfindlichkeit - Google Patents

Kapillardetektorzelle mit abbildenden Elementen zur Optimierung der Empfindlichkeit

Info

Publication number
DE69331619D1
DE69331619D1 DE69331619T DE69331619T DE69331619D1 DE 69331619 D1 DE69331619 D1 DE 69331619D1 DE 69331619 T DE69331619 T DE 69331619T DE 69331619 T DE69331619 T DE 69331619T DE 69331619 D1 DE69331619 D1 DE 69331619D1
Authority
DE
Germany
Prior art keywords
imaging elements
detector cell
optimize sensitivity
capillary detector
capillary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331619T
Other languages
English (en)
Other versions
DE69331619T2 (de
Inventor
Stephen E Moring
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
PE Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PE Corp filed Critical PE Corp
Publication of DE69331619D1 publication Critical patent/DE69331619D1/de
Application granted granted Critical
Publication of DE69331619T2 publication Critical patent/DE69331619T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G01N2021/052—Tubular type; cavity type; multireflective
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Optical Measuring Cells (AREA)
DE69331619T 1992-10-23 1993-10-07 Kapillardetektorzelle mit abbildenden Elementen zur Optimierung der Empfindlichkeit Expired - Lifetime DE69331619T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/965,827 US5274227A (en) 1992-10-23 1992-10-23 Capillary detector cell having imaging elements positioned to optimize sensitivity

Publications (2)

Publication Number Publication Date
DE69331619D1 true DE69331619D1 (de) 2002-04-04
DE69331619T2 DE69331619T2 (de) 2002-10-17

Family

ID=25510554

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331619T Expired - Lifetime DE69331619T2 (de) 1992-10-23 1993-10-07 Kapillardetektorzelle mit abbildenden Elementen zur Optimierung der Empfindlichkeit

Country Status (4)

Country Link
US (1) US5274227A (de)
EP (1) EP0594327B1 (de)
JP (1) JP3186375B2 (de)
DE (1) DE69331619T2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5269901A (en) * 1992-11-13 1993-12-14 Bio-Rad Laboratories, Inc. HPCE capillary cartridge for uncoiled capillaries with liquid coolant
EP0597152A1 (de) * 1992-11-13 1994-05-18 Jean-Pierre Chervet Optimierung einer mikrodurchflusszelle
US5495541A (en) * 1994-04-19 1996-02-27 Murray; Steven C. Optical delivery device with high numerical aperture curved waveguide
SE9703780D0 (sv) * 1997-10-17 1997-10-17 Tms Chem Ab Capillary based immunoassay
US6224830B1 (en) 1998-01-30 2001-05-01 The Governors Of The University Of Alberta Absorbance cell for microfluid devices
US6281975B1 (en) 2000-03-07 2001-08-28 Eldex Laboratories, Inc. Capillary flow cell with bulbous ends
CA2468850A1 (en) * 2001-12-04 2003-07-31 Lifepoint, Inc. Device and method for the identification of analytes in bodily fluids
GB0219248D0 (en) * 2002-08-17 2002-09-25 Univ York OPtical assembly and method for detection of light transmission
US6833062B2 (en) * 2003-02-28 2004-12-21 Combisep, Inc. Multiplexed, absorbance-based capillary electrophoresis system and method
JP4061241B2 (ja) * 2003-05-13 2008-03-12 ジーエルサイエンス株式会社 キャピラリーチューブフローセル
DE10322066B4 (de) * 2003-05-15 2005-04-21 SunChrom Wissenschaftliche Geräte GmbH Mikro-Durchflußmeßzelle für Photometer
US20070269162A1 (en) * 2006-05-18 2007-11-22 General Dynamics Advanced Information Systems Optical fiber cable to inject or extract light
JP4964647B2 (ja) * 2007-03-30 2012-07-04 ジーエルサイエンス株式会社 蛍光検出装置
DE102008000504A1 (de) 2008-03-04 2009-09-17 Agilent Technologies Inc., Santa Clara Kapillarröhre mit Anformung zur lokalen Variation eines Kapillardurchmessers
US8564768B2 (en) * 2009-04-17 2013-10-22 Schlumberger Technology Corporation High pressure and high temperature optical spectroscopy cell using spherical surfaced lenses in direct contact with a fluid pathway
EP2433120A1 (de) * 2009-05-20 2012-03-28 Agilent Technologies, Inc. Durchflusszelle zur strahlendetektion in einer zellwand
JP5534214B2 (ja) * 2009-10-05 2014-06-25 ベイバイオサイエンス株式会社 フローサイトメータおよびフローサイトメトリ方法
WO2016081727A1 (en) * 2014-11-20 2016-05-26 Drexel University Flow cells and methods of measuring an absorption spectrum of a sample
US10901228B2 (en) * 2017-06-27 2021-01-26 The Boeing Company Cavity with curved beam replicator and method of determining a characteristic of a medium therein

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4747652A (en) * 1981-04-27 1988-05-31 Raychem Corporation Optical fiber coupler
US5073345A (en) * 1983-05-31 1991-12-17 The Perkin Elmer Corporation Light detector apparatus
DE3447437A1 (de) * 1983-12-24 1985-07-11 Inotech AG, Wohlen Verfahren und vorrichtung zum fuehren und sammeln von licht in der fotometrie o.dgl.
US4747687A (en) * 1984-06-08 1988-05-31 Milton Roy Company Ball cell windows for spectrophotometers
EP0186755A3 (de) * 1984-11-26 1986-07-23 Kontron-Holding Ag Durchflusszelle
FR2577317B1 (fr) * 1985-02-08 1987-03-06 Inst Rech Hydrologique Appareil de mesure de la turbidite d'un liquide en flux continu.
US4856864A (en) * 1985-07-11 1989-08-15 Raychem Corporation Optical fiber distribution network including non-destructive taps and method of using same
US5239360A (en) * 1988-10-21 1993-08-24 Applied Biosystems, Inc. Lens for capillary electrophoresis and chromatography
DE69006091T2 (de) * 1989-04-14 1994-05-05 Kontron Instr Holding Kapillare Durchflusszelle.
EP0422448B1 (de) * 1989-09-29 1995-11-29 Waters Investments Limited Vorrichtung zum Messen der Lichtabsorption oder Fluoreszenz in flüssigen Proben

Also Published As

Publication number Publication date
JP3186375B2 (ja) 2001-07-11
US5274227A (en) 1993-12-28
EP0594327A1 (de) 1994-04-27
JPH0749340A (ja) 1995-02-21
EP0594327B1 (de) 2002-02-27
DE69331619T2 (de) 2002-10-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLERA CORP., FOSTER CITY, CALIF., US

8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

8380 Miscellaneous part iii

Free format text: PFANDRECHT

8380 Miscellaneous part iii

Free format text: PFANDRECHT AUFGEHOBEN