DE69318636T2 - Substituierte Aminothienopyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel - Google Patents

Substituierte Aminothienopyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Info

Publication number
DE69318636T2
DE69318636T2 DE69318636T DE69318636T DE69318636T2 DE 69318636 T2 DE69318636 T2 DE 69318636T2 DE 69318636 T DE69318636 T DE 69318636T DE 69318636 T DE69318636 T DE 69318636T DE 69318636 T2 DE69318636 T2 DE 69318636T2
Authority
DE
Germany
Prior art keywords
preparation
compounds
useful
aminothienopyridines
medicines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69318636T
Other languages
English (en)
Other versions
DE69318636D1 (de
Inventor
Richard Charles Effland
Joseph Thomas Klein
Lawrence Leo Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DE69318636D1 publication Critical patent/DE69318636D1/de
Publication of DE69318636T2 publication Critical patent/DE69318636T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyridine Compounds (AREA)
DE69318636T 1992-07-20 1993-07-13 Substituierte Aminothienopyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel Expired - Lifetime DE69318636T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/917,247 US5252581A (en) 1992-07-20 1992-07-20 Substituted aminothienopyridines, pharmaceutical composition and use

Publications (2)

Publication Number Publication Date
DE69318636D1 DE69318636D1 (de) 1998-06-25
DE69318636T2 true DE69318636T2 (de) 1998-11-26

Family

ID=25438534

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69318636T Expired - Lifetime DE69318636T2 (de) 1992-07-20 1993-07-13 Substituierte Aminothienopyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Country Status (13)

Country Link
US (3) US5252581A (de)
EP (1) EP0581106B1 (de)
JP (1) JP2757745B2 (de)
KR (1) KR100292212B1 (de)
AT (1) ATE166355T1 (de)
AU (1) AU662640B2 (de)
CA (1) CA2100812C (de)
DE (1) DE69318636T2 (de)
DK (1) DK0581106T3 (de)
ES (1) ES2116371T3 (de)
MX (1) MX9304353A (de)
NZ (1) NZ248170A (de)
TW (1) TW243450B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252581A (en) * 1992-07-20 1993-10-12 Hoechst-Roussel Pharmaceuticals Inc. Substituted aminothienopyridines, pharmaceutical composition and use
US5272148A (en) * 1992-09-09 1993-12-21 Hoechst-Roussel Pharmaceuticals Incorporated Heteroarenylpiperazines
EP0599697A1 (de) * 1992-11-24 1994-06-01 Synthelabo Pyrrol-Derivate, ihre Herstellung und therapeutische Verwendung
US5334596A (en) * 1993-05-11 1994-08-02 Merck & Co., Inc. Fibrinogen receptor antagonists
US20070197651A1 (en) * 1998-03-09 2007-08-23 Tufts University Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors
US6242456B1 (en) 1998-03-09 2001-06-05 Trustees Of Tufts College Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors
US20060167114A1 (en) * 1998-03-09 2006-07-27 Louis Shuster Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors
US6867203B2 (en) 1998-12-29 2005-03-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
US7875627B2 (en) * 2004-12-07 2011-01-25 Abbott Laboratories Thienopyridyl compounds that inhibit vanilloid receptor subtype 1 (VR1) and uses thereof
KR20080052630A (ko) * 2005-09-01 2008-06-11 어레이 바이오파마 인크. Raf 억제제 화합물 및 그의 사용 방법
MX2008011220A (es) 2006-03-07 2008-09-11 Array Biopharma Inc Compuestos de pirazol heterobiciclicos y metodos de uso.
MX2012009377A (es) 2010-02-11 2012-09-12 Univ Vanderbilt Benzotiazoles y azabenzotiazoles como potenciadores alostericos mglur4, composiciones y metodos para tratar la disfuncion neurologica.
JP5102401B1 (ja) 2012-03-30 2012-12-19 森下仁丹株式会社 大腸特異崩壊性カプセル
US11358971B2 (en) 2019-07-03 2022-06-14 H. Lundbeck A/S Prodrugs of modulators of the NMDA receptor
US11466027B2 (en) 2019-07-03 2022-10-11 H. Lundbeck A/S Modulators of the NMDA receptor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US281152A (en) * 1883-07-10 Safety-pin
US2811527A (en) * 1955-11-16 1957-10-29 Olin Mathieson Derivatives of thieno (3, 2-b) pyridine and method of preparing same
NO140499C (no) * 1973-07-23 1979-09-12 Takeda Chemical Industries Ltd Analogifremgangsmaate til fremstilling av thienopyridinkarboksylsyrederivcater med terapeutisk aktivitet
US3952989A (en) * 1974-11-26 1976-04-27 Bannister Hatcher Constance L Adjustable reading material stand
FR2440738A1 (fr) * 1978-11-13 1980-06-06 Parcor Medicament a base de derives des thieno (2,3-c) et (3,2-c) pyridines
US5026698A (en) * 1988-11-02 1991-06-25 Nissan Chemical Industries, Ltd. Thienopyridine type mevalonolactones
US5252581A (en) * 1992-07-20 1993-10-12 Hoechst-Roussel Pharmaceuticals Inc. Substituted aminothienopyridines, pharmaceutical composition and use

Also Published As

Publication number Publication date
DK0581106T3 (da) 1999-02-15
ATE166355T1 (de) 1998-06-15
CA2100812A1 (en) 1994-01-21
JPH06179681A (ja) 1994-06-28
EP0581106A1 (de) 1994-02-02
JP2757745B2 (ja) 1998-05-25
MX9304353A (es) 1994-02-28
TW243450B (de) 1995-03-21
US5856335A (en) 1999-01-05
NZ248170A (en) 1995-12-21
DE69318636D1 (de) 1998-06-25
EP0581106B1 (de) 1998-05-20
US5252581A (en) 1993-10-12
US5519032A (en) 1996-05-21
KR100292212B1 (ko) 2001-09-17
ES2116371T3 (es) 1998-07-16
AU4200193A (en) 1994-01-27
CA2100812C (en) 2006-11-14
KR940002249A (ko) 1994-02-17
AU662640B2 (en) 1995-09-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMACEUTICALS INC., BRIDGEWATER, N.J, US

8327 Change in the person/name/address of the patent owner

Owner name: AVENTISUB II INC., GREENVILLE, DEL., US

8328 Change in the person/name/address of the agent

Representative=s name: DERZEIT KEIN VERTRETER BESTELLT