DE69311725T2 - Verfahren zur herstellung von optisch aktiven aminodiol - Google Patents

Verfahren zur herstellung von optisch aktiven aminodiol

Info

Publication number
DE69311725T2
DE69311725T2 DE69311725T DE69311725T DE69311725T2 DE 69311725 T2 DE69311725 T2 DE 69311725T2 DE 69311725 T DE69311725 T DE 69311725T DE 69311725 T DE69311725 T DE 69311725T DE 69311725 T2 DE69311725 T2 DE 69311725T2
Authority
DE
Germany
Prior art keywords
pct
beta
optically active
producing optically
cyclopentanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69311725T
Other languages
English (en)
Other versions
DE69311725D1 (de
Inventor
David Joszef Tapolczay
Clive Alwin Meerholz
John Peter Turnbull
Bernard Charles Halter
Mark Brian Schilling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE69311725D1 publication Critical patent/DE69311725D1/de
Publication of DE69311725T2 publication Critical patent/DE69311725T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/74—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE69311725T 1992-08-21 1993-08-19 Verfahren zur herstellung von optisch aktiven aminodiol Expired - Lifetime DE69311725T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929217823A GB9217823D0 (en) 1992-08-21 1992-08-21 Chemical process
PCT/EP1993/002219 WO1994004486A1 (en) 1992-08-21 1993-08-19 Chemical process for preparing an optically active aminodiol

Publications (2)

Publication Number Publication Date
DE69311725D1 DE69311725D1 (de) 1997-07-24
DE69311725T2 true DE69311725T2 (de) 1997-10-30

Family

ID=10720746

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69311725T Expired - Lifetime DE69311725T2 (de) 1992-08-21 1993-08-19 Verfahren zur herstellung von optisch aktiven aminodiol

Country Status (11)

Country Link
US (1) US5659075A (de)
EP (1) EP0655994B1 (de)
JP (1) JP3296560B2 (de)
AT (1) ATE154589T1 (de)
AU (1) AU4950193A (de)
DE (1) DE69311725T2 (de)
DK (1) DK0655994T3 (de)
ES (1) ES2105312T3 (de)
GB (1) GB9217823D0 (de)
GR (1) GR3024069T3 (de)
WO (1) WO1994004486A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK284810B6 (sk) 1997-05-13 2005-12-01 Lonza Ag Spôsob výroby (1S,4R)- alebo (1R,4S)-4-(2-amino-6-chlór-9-H- purín-9-yl)-2-cyklopentén-1-metanolu

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3474093A (en) * 1966-05-03 1969-10-21 American Home Prod Enamine adducts of n-acyloxy-n-acylaminoacetanilide
DE2252674C3 (de) * 1972-10-27 1981-02-05 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Aldehyden aus Olefinen
GB8815265D0 (en) * 1988-06-27 1988-08-03 Wellcome Found Therapeutic nucleosides

Also Published As

Publication number Publication date
US5659075A (en) 1997-08-19
JPH08500583A (ja) 1996-01-23
GR3024069T3 (en) 1997-10-31
EP0655994A1 (de) 1995-06-07
EP0655994B1 (de) 1997-06-18
ES2105312T3 (es) 1997-10-16
DK0655994T3 (da) 1997-12-29
ATE154589T1 (de) 1997-07-15
JP3296560B2 (ja) 2002-07-02
DE69311725D1 (de) 1997-07-24
WO1994004486A1 (en) 1994-03-03
GB9217823D0 (en) 1992-10-07
AU4950193A (en) 1994-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition