DE69309377D1 - Mikronährstoff-Zusammensetzungen - Google Patents

Mikronährstoff-Zusammensetzungen

Info

Publication number
DE69309377D1
DE69309377D1 DE69309377T DE69309377T DE69309377D1 DE 69309377 D1 DE69309377 D1 DE 69309377D1 DE 69309377 T DE69309377 T DE 69309377T DE 69309377 T DE69309377 T DE 69309377T DE 69309377 D1 DE69309377 D1 DE 69309377D1
Authority
DE
Germany
Prior art keywords
micronutrient
compositions
binder
densifying
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69309377T
Other languages
English (en)
Other versions
DE69309377T2 (de
Inventor
William Joseph Mergens
Joseph Edward Raymond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE69309377D1 publication Critical patent/DE69309377D1/de
Publication of DE69309377T2 publication Critical patent/DE69309377T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Grain Derivatives (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Fertilizers (AREA)
  • Fodder In General (AREA)
DE69309377T 1992-09-23 1993-09-18 Mikronährstoff-Zusammensetzungen Expired - Lifetime DE69309377T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95038192A 1992-09-23 1992-09-23

Publications (2)

Publication Number Publication Date
DE69309377D1 true DE69309377D1 (de) 1997-05-07
DE69309377T2 DE69309377T2 (de) 1997-09-18

Family

ID=25490365

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69309377T Expired - Lifetime DE69309377T2 (de) 1992-09-23 1993-09-18 Mikronährstoff-Zusammensetzungen

Country Status (7)

Country Link
US (1) US5397576A (de)
EP (1) EP0589375B1 (de)
JP (1) JP3556689B2 (de)
AT (1) ATE150962T1 (de)
DE (1) DE69309377T2 (de)
DK (1) DK0589375T3 (de)
ES (1) ES2101185T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0995448A (ja) * 1995-09-29 1997-04-08 Calpis Food Ind Co Ltd:The 血中ビオチン濃度の増加方法およびビオチン含有飲食品
DE19651734C2 (de) * 1996-12-12 1999-05-12 Dds Drug Delivery Service Ges Zubereitung in Form eines Polymer-Hilfsstoff-Compounds und/oder eines Polymer-Wirkstoff-Compounds und Verfahren zu dessen Herstellung sowie dessen Verwendung zur Herstellung von Tabletten und/oder anderen größeren Matrixeinheiten
WO2000033673A1 (en) * 1998-12-08 2000-06-15 Csir Microparticles and process for making microparticles
GB9922271D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Formulation
JP2001181211A (ja) * 1999-12-24 2001-07-03 Sumitomo Chem Co Ltd 水溶性ビタミン粉剤
GB0003782D0 (en) * 2000-02-17 2000-04-05 Dumex Ltd As Process
US6773733B2 (en) 2001-03-26 2004-08-10 Loders Croklaan Usa Llc Structured particulate systems
EP1399132A1 (de) * 2001-06-08 2004-03-24 Powderject Vaccines, Inc. Herstellung von harten und dichten partikeln
CN103889247B (zh) 2011-09-08 2016-06-22 美国微营养有限责任公司 微量营养素补充剂
EP3982936A1 (de) 2019-06-17 2022-04-20 DSM IP Assets B.V. Feste pharmazeutische darreichungsform mit sprühgetrocknetem vitamin b12
EP3982935A1 (de) 2019-06-17 2022-04-20 DSM IP Assets B.V. Zusammensetzung mit metformin-hcl, vitamin b12 und mindestens einem flussadditiv
CN113180244A (zh) * 2021-05-31 2021-07-30 临汾市力圣生物科技开发有限公司 一种叶酸干燥工艺

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3175948A (en) * 1963-01-10 1965-03-30 Hoffmann La Roche Multivitamin tablets and premixes
US3293132A (en) * 1963-03-25 1966-12-20 Merck & Co Inc Spray dried vitamin compositions and method of preparation
US3396226A (en) * 1965-01-06 1968-08-06 Hoffmann La Roche Nongranulated compressed tablets of ascorbic acid with microcrystalline cellulose
US3914430A (en) * 1972-04-10 1975-10-21 Hoffmann La Roche Free-flowing, high density, agglomerated vitamin E powder compositions
US4489026A (en) * 1982-09-07 1984-12-18 The Upjohn Company Process for preparing solid unit dosage forms of ultra-low dose drugs
US4486435A (en) * 1983-05-16 1984-12-04 Basf Wyandotte Corporation Spray-dried vitamin powders using hydrophobic silica
EP0160087A4 (de) * 1983-10-24 1987-06-29 Basf Wyandotte Corp Verfahren zur herstellung sprühgetrockneter pulver, enthaltend ein wasserlösliches vitamin und so hergestellte pulver.
US4533674A (en) * 1983-10-24 1985-08-06 Basf Wyandotte Corporation Process for preparing a sugar and starch free spray-dried vitamin C powder containing 90 percent ascorbic acid
CA1279574C (en) * 1985-04-17 1991-01-29 Jeffrey L. Finnan Process for lubricating water-soluble vitamin powders
IT1229930B (it) * 1988-10-14 1991-09-16 Dox Al Italia Spa Procedimento per la preparazione di miscele per uso alimentare e mangimistico comprendenti sostanze attive distribuite in modo uniforme
DE69001003T2 (de) * 1989-08-31 1993-06-17 Takeda Chemical Industries Ltd Vitamin-b12-zusammensetzung.
US4994458A (en) * 1990-04-30 1991-02-19 Basf Corporation Process for rotary fluid bed granulation of riboflavin
US5000888A (en) * 1990-05-23 1991-03-19 Basf Corporation Process for spray drying riboflavin to produce a granulate product having low binder content

Also Published As

Publication number Publication date
EP0589375A1 (de) 1994-03-30
DK0589375T3 (da) 1997-09-22
US5397576A (en) 1995-03-14
DE69309377T2 (de) 1997-09-18
ES2101185T3 (es) 1997-07-01
ATE150962T1 (de) 1997-04-15
EP0589375B1 (de) 1997-04-02
JP3556689B2 (ja) 2004-08-18
JPH06197733A (ja) 1994-07-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DSM IP ASSETS B.V., TE HEERLEN, NL