DE69301468T2 - Peptide mit Bradykinin-antagonistischer Wirkung - Google Patents
Peptide mit Bradykinin-antagonistischer WirkungInfo
- Publication number
- DE69301468T2 DE69301468T2 DE69301468T DE69301468T DE69301468T2 DE 69301468 T2 DE69301468 T2 DE 69301468T2 DE 69301468 T DE69301468 T DE 69301468T DE 69301468 T DE69301468 T DE 69301468T DE 69301468 T2 DE69301468 T2 DE 69301468T2
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- antagonistic activity
- bradykinin antagonistic
- arg
- bradykinin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102400000967 Bradykinin Human genes 0.000 title 1
- 101800004538 Bradykinin Proteins 0.000 title 1
- QXZGBUJJYSLZLT-UHFFFAOYSA-N H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH Natural products NC(N)=NCCCC(N)C(=O)N1CCCC1C(=O)N1C(C(=O)NCC(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CO)C(=O)N2C(CCC2)C(=O)NC(CC=2C=CC=CC=2)C(=O)NC(CCCN=C(N)N)C(O)=O)CCC1 QXZGBUJJYSLZLT-UHFFFAOYSA-N 0.000 title 1
- 230000003042 antagnostic effect Effects 0.000 title 1
- QXZGBUJJYSLZLT-FDISYFBBSA-N bradykinin Chemical compound NC(=N)NCCC[C@H](N)C(=O)N1CCC[C@H]1C(=O)N1[C@H](C(=O)NCC(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CO)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)CCC1 QXZGBUJJYSLZLT-FDISYFBBSA-N 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 241000534944 Thia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9200438A FR2686343B1 (fr) | 1992-01-17 | 1992-01-17 | Nouveaux derives pseudopeptidiques a activite antagoniste de la bradykinine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69301468D1 DE69301468D1 (de) | 1996-03-21 |
| DE69301468T2 true DE69301468T2 (de) | 1996-09-05 |
Family
ID=9425706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69301468T Expired - Fee Related DE69301468T2 (de) | 1992-01-17 | 1993-01-15 | Peptide mit Bradykinin-antagonistischer Wirkung |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5409899A (de) |
| EP (1) | EP0552106B1 (de) |
| JP (1) | JPH0730112B2 (de) |
| AT (1) | ATE133960T1 (de) |
| AU (1) | AU653460B2 (de) |
| CA (1) | CA2087379A1 (de) |
| DE (1) | DE69301468T2 (de) |
| DK (1) | DK0552106T3 (de) |
| ES (1) | ES2086195T3 (de) |
| FR (1) | FR2686343B1 (de) |
| GR (1) | GR3019372T3 (de) |
| NZ (1) | NZ245685A (de) |
| ZA (1) | ZA93275B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2692581B1 (fr) * | 1992-06-18 | 1994-08-19 | Adir | Nouveaux dérivés peptidiques à activité antagoniste de la bradykinine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| CA2221865C (en) * | 1995-06-09 | 2007-12-11 | The Regents Of The University Of Michigan | Bradykinin analogs as selective thrombin inhibitors |
| FR2737408B1 (fr) * | 1995-07-31 | 1997-09-05 | Oreal | Utilisation d'un antagoniste de bradykinine dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue |
| DE19612067A1 (de) * | 1996-03-27 | 1997-10-02 | Hoechst Ag | Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen |
| DE19642289A1 (de) | 1996-10-14 | 1998-04-16 | Hoechst Ag | Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimer'schen Krankheit |
| US6982249B1 (en) | 1997-04-23 | 2006-01-03 | The Regents Of The University Of Michigan | Bradykinin analogs as selective inhibitors of cell activation |
| US6699486B1 (en) | 1999-11-18 | 2004-03-02 | Bolla Corporation | Treatment or prevention of photoaging and skin cancer |
| US7105172B1 (en) | 1999-11-18 | 2006-09-12 | Bolla John D | Treatment of rosacea |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE370453C (de) * | 1923-03-03 | Franz Puening | Destillationsverfahren | |
| JPS507057B1 (de) * | 1970-10-28 | 1975-03-20 |
-
1992
- 1992-01-17 FR FR9200438A patent/FR2686343B1/fr not_active Expired - Fee Related
-
1993
- 1993-01-13 US US08/006,151 patent/US5409899A/en not_active Expired - Fee Related
- 1993-01-14 JP JP5005261A patent/JPH0730112B2/ja not_active Expired - Lifetime
- 1993-01-15 DK DK93400086.0T patent/DK0552106T3/da active
- 1993-01-15 CA CA002087379A patent/CA2087379A1/fr not_active Abandoned
- 1993-01-15 DE DE69301468T patent/DE69301468T2/de not_active Expired - Fee Related
- 1993-01-15 ES ES93400086T patent/ES2086195T3/es not_active Expired - Lifetime
- 1993-01-15 AT AT93400086T patent/ATE133960T1/de not_active IP Right Cessation
- 1993-01-15 EP EP93400086A patent/EP0552106B1/de not_active Expired - Lifetime
- 1993-01-15 ZA ZA93275A patent/ZA93275B/xx unknown
- 1993-01-15 AU AU31844/93A patent/AU653460B2/en not_active Ceased
- 1993-01-15 NZ NZ24568593A patent/NZ245685A/en unknown
-
1996
- 1996-03-20 GR GR960400772T patent/GR3019372T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0552106A1 (de) | 1993-07-21 |
| AU653460B2 (en) | 1994-09-29 |
| ATE133960T1 (de) | 1996-02-15 |
| CA2087379A1 (fr) | 1993-07-18 |
| NZ245685A (en) | 1994-07-26 |
| AU3184493A (en) | 1993-07-22 |
| JPH0730112B2 (ja) | 1995-04-05 |
| DK0552106T3 (da) | 1996-06-24 |
| GR3019372T3 (en) | 1996-06-30 |
| FR2686343B1 (fr) | 1994-03-11 |
| EP0552106B1 (de) | 1996-02-07 |
| US5409899A (en) | 1995-04-25 |
| DE69301468D1 (de) | 1996-03-21 |
| JPH06179697A (ja) | 1994-06-28 |
| ZA93275B (en) | 1993-08-23 |
| FR2686343A1 (fr) | 1993-07-23 |
| ES2086195T3 (es) | 1996-06-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |