DE69226550T2 - Methode zur Steigerung des Anteils einer kristallinen organischen Verbindung, die unkristallisiert bleibt, in einem teilchenförmigen Kompositprodukt und Unterdrückung der Rekristallisation - Google Patents

Methode zur Steigerung des Anteils einer kristallinen organischen Verbindung, die unkristallisiert bleibt, in einem teilchenförmigen Kompositprodukt und Unterdrückung der Rekristallisation

Info

Publication number
DE69226550T2
DE69226550T2 DE69226550T DE69226550T DE69226550T2 DE 69226550 T2 DE69226550 T2 DE 69226550T2 DE 69226550 T DE69226550 T DE 69226550T DE 69226550 T DE69226550 T DE 69226550T DE 69226550 T2 DE69226550 T2 DE 69226550T2
Authority
DE
Germany
Prior art keywords
proportion
increasing
organic compound
composite product
crystalline organic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69226550T
Other languages
English (en)
Other versions
DE69226550D1 (de
Inventor
Takafumi Ishizaka
Yuji Kikuchi
Masumi Koishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nara Machinery Co Ltd
Original Assignee
Nara Machinery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nara Machinery Co Ltd filed Critical Nara Machinery Co Ltd
Application granted granted Critical
Publication of DE69226550D1 publication Critical patent/DE69226550D1/de
Publication of DE69226550T2 publication Critical patent/DE69226550T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/003—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/10—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in stationary drums or troughs, provided with kneading or mixing appliances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
DE69226550T 1991-03-26 1992-03-24 Methode zur Steigerung des Anteils einer kristallinen organischen Verbindung, die unkristallisiert bleibt, in einem teilchenförmigen Kompositprodukt und Unterdrückung der Rekristallisation Expired - Fee Related DE69226550T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3086332A JP2941081B2 (ja) 1991-03-26 1991-03-26 結晶性有機化合物の非晶質割合の増加と再結晶化を抑制する方法

Publications (2)

Publication Number Publication Date
DE69226550D1 DE69226550D1 (de) 1998-09-17
DE69226550T2 true DE69226550T2 (de) 1998-12-24

Family

ID=13883886

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69226550T Expired - Fee Related DE69226550T2 (de) 1991-03-26 1992-03-24 Methode zur Steigerung des Anteils einer kristallinen organischen Verbindung, die unkristallisiert bleibt, in einem teilchenförmigen Kompositprodukt und Unterdrückung der Rekristallisation

Country Status (5)

Country Link
US (1) US5336271A (de)
EP (1) EP0506219B1 (de)
JP (1) JP2941081B2 (de)
KR (1) KR950011823B1 (de)
DE (1) DE69226550T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1274101B (it) * 1994-11-09 1997-07-15 G S Srl Coating System Metodo ed apparecchiatura per la sferonizzazione e l'essiccamento di articoli.
JP2958292B2 (ja) * 1997-10-02 1999-10-06 核燃料サイクル開発機構 ウラン・プルトニウム混合酸化物の均一化混合方法
JP3390863B2 (ja) * 1997-12-01 2003-03-31 株式会社奈良機械製作所 複合固体粒子とその製造方法
KR100549095B1 (ko) * 1998-07-17 2006-02-06 얀센 파마슈티카 엔.브이. 항진균제 및 중합체로 코팅된 코어를 갖는 펠릿
JP2003025325A (ja) * 2001-07-23 2003-01-29 Sumitomo Bakelite Co Ltd 複合粒子の製造方法
US20050191357A1 (en) * 2002-03-20 2005-09-01 Yoshiaki Kawashima Method of manufacturing chemical-containing composite particles
US7425287B2 (en) 2003-01-24 2008-09-16 Showa Denko K.K. Surface modification method for inorganic oxide powder, powder produced by the method and use of the powder
JP4521654B2 (ja) * 2003-04-24 2010-08-11 株式会社ダルトン 造粒物および造粒方法
WO2004110405A1 (ja) * 2003-06-11 2004-12-23 Nara Machinery Co., Ltd. 薬物ナノ粒子、その粒子を使用した薬剤の製造方法および薬剤の製造装置
JP2005028356A (ja) * 2003-06-17 2005-02-03 Hosokawa Funtai Gijutsu Kenkyusho:Kk 複合粒子の製造方法、並びにその方法により製造された複合粒子
DE102005036211A1 (de) * 2005-08-02 2007-02-08 Lanxess Deutschland Gmbh Strahlmühle mit integriertem dynamischen Sichter
JP5781723B2 (ja) * 2009-03-24 2015-09-24 株式会社前川製作所 エアサイクル冷凍システム
WO2014203497A1 (ja) * 2013-06-20 2014-12-24 株式会社奈良機械製作所 粉体処理装置
JP2016034922A (ja) * 2014-08-02 2016-03-17 敏幸 丹羽 医薬品原末と医薬品添加剤の複合粒子の製造方法及び同方法で製造された複合粒子
JP7184627B2 (ja) * 2018-12-18 2022-12-06 花王株式会社 セルロース複合粉末の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA641298A (en) * 1962-05-15 Kimits Ladislaus Process for the preparation of finely divided aluminum pigment pastes
US3688991A (en) * 1970-07-30 1972-09-05 Norwood H Andrews Jet and anvil comminuting apparatus, and method
US3713593A (en) * 1970-08-11 1973-01-30 Freeport Sulphur Co Fine media milling process
JPS53102883A (en) * 1977-02-21 1978-09-07 Toray Ind Inc Chemical hammer agent and its use
US4298399A (en) * 1980-06-11 1981-11-03 International Pigment Processing Corp. Process for salt grinding of pigments
DE3687219T2 (de) * 1985-10-07 1993-04-08 Nara Machinery Co Ltd Methode zur verbesserung der oberflaechenqualitaet von festen teilchen und vorrichtung dazu.
DE68916497T2 (de) * 1988-09-30 1994-11-17 Rhone Poulenc Rorer Ltd Pharmazeutisches Granulat.
JPH0298366A (ja) * 1988-10-05 1990-04-10 Terumo Corp 使用済のチューブ付医療用針用プロテクター及びプロテクターを備えたチューブ付医療用針

Also Published As

Publication number Publication date
US5336271A (en) 1994-08-09
KR920017632A (ko) 1992-10-21
EP0506219B1 (de) 1998-08-12
JPH06210152A (ja) 1994-08-02
EP0506219A3 (en) 1993-08-11
JP2941081B2 (ja) 1999-08-25
DE69226550D1 (de) 1998-09-17
KR950011823B1 (ko) 1995-10-11
EP0506219A2 (de) 1992-09-30

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8339 Ceased/non-payment of the annual fee