DE69226091D1 - Stickstoffoxide von aza- und diazaanthracendionderivaten, deren herstellung und deren verwendung als antitumormittel - Google Patents

Stickstoffoxide von aza- und diazaanthracendionderivaten, deren herstellung und deren verwendung als antitumormittel

Info

Publication number
DE69226091D1
DE69226091D1 DE69226091T DE69226091T DE69226091D1 DE 69226091 D1 DE69226091 D1 DE 69226091D1 DE 69226091 T DE69226091 T DE 69226091T DE 69226091 T DE69226091 T DE 69226091T DE 69226091 D1 DE69226091 D1 DE 69226091D1
Authority
DE
Germany
Prior art keywords
aza
nitrogen oxides
diazaanthracendion
derivatives
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69226091T
Other languages
English (en)
Inventor
Carmelo Gandolfi
Ernesto Menta
Ambrogio Oliva
Silvano Spinelli
Sergio Tognella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics SpA
Original Assignee
Roche Diagnostics SpA
Boehringer Mannheim Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics SpA, Boehringer Mannheim Italia SpA filed Critical Roche Diagnostics SpA
Application granted granted Critical
Publication of DE69226091D1 publication Critical patent/DE69226091D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69226091T 1991-03-08 1992-02-27 Stickstoffoxide von aza- und diazaanthracendionderivaten, deren herstellung und deren verwendung als antitumormittel Expired - Lifetime DE69226091D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI910618A IT1244755B (it) 1991-03-08 1991-03-08 Azoto ossidi di derivati aza- e diaza-antracenedionici come farmaci antitumorali
PCT/EP1992/000421 WO1992015566A1 (en) 1991-03-08 1992-02-27 Nitrogen oxides of aza- and diaza-anthracenedione derivatives as antitumor agents

Publications (1)

Publication Number Publication Date
DE69226091D1 true DE69226091D1 (de) 1998-08-06

Family

ID=11358951

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69226091T Expired - Lifetime DE69226091D1 (de) 1991-03-08 1992-02-27 Stickstoffoxide von aza- und diazaanthracendionderivaten, deren herstellung und deren verwendung als antitumormittel

Country Status (13)

Country Link
EP (1) EP0639183B1 (de)
JP (1) JPH06505244A (de)
AT (2) ATE167856T1 (de)
AU (1) AU1276892A (de)
DE (1) DE69226091D1 (de)
IE (1) IE920704A1 (de)
IL (1) IL101157A (de)
IT (1) IT1244755B (de)
MX (1) MX9200919A (de)
NZ (1) NZ241856A (de)
TW (1) TW197426B (de)
WO (1) WO1992015566A1 (de)
ZA (1) ZA921648B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104557704B (zh) * 2013-10-28 2017-05-10 北京凯莱天成医药科技有限公司 一种匹杉琼马来酸盐的制备方法
CN103787970A (zh) * 2014-01-14 2014-05-14 北京万全德众医药生物技术有限公司 一锅煮法制备6，9-二氟苯并异喹啉-5，10-二酮的工艺
CN106366036B (zh) * 2016-08-18 2019-07-09 湖北丽益医药科技有限公司 6,9-双[(2-氨基乙基)氨基]苯并[g]异喹啉-5,10-二酮二马来酸盐及其合成工艺

Also Published As

Publication number Publication date
IT1244755B (it) 1994-08-08
IL101157A (en) 1996-07-23
EP0639183A1 (de) 1995-02-22
JPH06505244A (ja) 1994-06-16
ZA921648B (en) 1992-11-25
ITMI910618A0 (it) 1991-03-08
WO1992015566A1 (en) 1992-09-17
IE920704A1 (en) 1992-09-09
ITMI910618A1 (it) 1992-09-08
MX9200919A (es) 1992-09-30
AU1276892A (en) 1992-10-06
TW197426B (de) 1993-01-01
ATE123220T1 (de) 1995-06-15
NZ241856A (en) 1994-12-22
ATE167856T1 (de) 1998-07-15
EP0639183B1 (de) 1998-07-01

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Legal Events

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8332 No legal effect for de