DE69224983D1 - Anti-wachstumsfaktor antikörper in der behandlung von gefässstenose - Google Patents

Anti-wachstumsfaktor antikörper in der behandlung von gefässstenose

Info

Publication number
DE69224983D1
DE69224983D1 DE69224983T DE69224983T DE69224983D1 DE 69224983 D1 DE69224983 D1 DE 69224983D1 DE 69224983 T DE69224983 T DE 69224983T DE 69224983 T DE69224983 T DE 69224983T DE 69224983 D1 DE69224983 D1 DE 69224983D1
Authority
DE
Germany
Prior art keywords
growth factor
vascular stenosis
treatment
antibodies
factor antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69224983T
Other languages
English (en)
Other versions
DE69224983T2 (de
Inventor
Russell Ross
Michael Reidy
Elaine Raines
Volkhard Lindner
Gordon A A Ferns
Christopher Jackson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington
Original Assignee
University of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington filed Critical University of Washington
Publication of DE69224983D1 publication Critical patent/DE69224983D1/de
Application granted granted Critical
Publication of DE69224983T2 publication Critical patent/DE69224983T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69224983T 1991-01-17 1992-01-17 Anti-wachstumsfaktor antikörper in der behandlung von gefässstenose Expired - Fee Related DE69224983T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64175891A 1991-01-17 1991-01-17
PCT/US1992/000438 WO1992012734A1 (en) 1991-01-17 1992-01-17 Anti-growth factor antibodies in the treatment of vascular stenosis

Publications (2)

Publication Number Publication Date
DE69224983D1 true DE69224983D1 (de) 1998-05-07
DE69224983T2 DE69224983T2 (de) 1998-07-30

Family

ID=24573729

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69224983T Expired - Fee Related DE69224983T2 (de) 1991-01-17 1992-01-17 Anti-wachstumsfaktor antikörper in der behandlung von gefässstenose
DE69232579T Expired - Fee Related DE69232579T2 (de) 1991-01-17 1992-01-17 Anti-Plättchen-Wachstumsfaktor-Antikörper in der Behandlung von Restenose

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69232579T Expired - Fee Related DE69232579T2 (de) 1991-01-17 1992-01-17 Anti-Plättchen-Wachstumsfaktor-Antikörper in der Behandlung von Restenose

Country Status (10)

Country Link
US (1) US5648076A (de)
EP (2) EP0798002B1 (de)
JP (2) JP3667752B2 (de)
AT (2) ATE164521T1 (de)
AU (1) AU665529B2 (de)
CA (1) CA2100876A1 (de)
DE (2) DE69224983T2 (de)
DK (2) DK0573510T3 (de)
ES (2) ES2174144T3 (de)
WO (1) WO1992012734A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770198A (en) * 1988-05-18 1998-06-23 The Research Foundation Of The State Of New York Platelet-specific chimeric 7E3 immunoglobulin
CN1186439A (zh) * 1995-06-07 1998-07-01 森特克公司 血小板特异性的嵌合性免疫球蛋白及其使用方法
US7241568B2 (en) 1996-04-03 2007-07-10 Kyowa Hakko Kogyo Co., Ltd. Anti-fibroblast growth factor-8 monoclonal antibody
AU6497198A (en) * 1997-02-14 1998-09-08 Boehringer Mannheim Gmbh Improved method for the reduction of neointima formation after angioplasty
EP1422243B1 (de) * 2001-06-28 2008-04-23 Kyowa Hakko Kogyo Co., Ltd Humanisierter antikörper gegen fibroblastenwachstumsfaktor 8 und fragment des antikörpers
PL1680140T3 (pl) * 2003-10-16 2011-11-30 Imclone Llc Inhibitory receptora-1 czynnika wzrostu fibroblastów i związane z nim sposoby leczenia
US9339593B2 (en) * 2007-01-11 2016-05-17 Robert L. Bjork, JR. Drug-eluting coronary artery stent coated with anti-platelet-derived growth factor antibodies overlaying extracellular matrix proteins with an outer coating of anti-inflammatory (calcineurin inhibitor) and/or anti-proliferatives
JP5602432B2 (ja) * 2007-01-11 2014-10-08 ロバート ラマール ジュニア ビョーク 経皮的冠動脈インターベンション用の多剤溶出冠動脈ステント
WO2016149103A1 (en) * 2015-03-13 2016-09-22 The Regents Of The University Of California Monoclonal antibody for prevention and/or treatment of astrovirus disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE116373T1 (de) * 1987-03-03 1995-01-15 Takeda Chemical Industries Ltd Monoklonaler antikörper, hybridomen, ihre herstellung und ihre verwendung.
CA1339356C (en) * 1988-02-02 1997-08-26 Lewis T. Williams Human platelet-derived growth factor receptor
US5268358A (en) * 1988-12-08 1993-12-07 Cor Therapeutics, Inc. PDGF receptor blocking peptides
AU6605690A (en) * 1989-10-27 1991-05-31 Du Pont Merck Pharmaceutical Company, The Monoclonal antibodies to basic fibroblast growth factor that inhibit its biological activity
JP4350370B2 (ja) * 2002-12-27 2009-10-21 株式会社半導体エネルギー研究所 電子回路及び電子機器

Also Published As

Publication number Publication date
WO1992012734A1 (en) 1992-08-06
DE69232579T2 (de) 2002-08-22
JP3667752B2 (ja) 2005-07-06
EP0573510B1 (de) 1998-04-01
AU1327492A (en) 1992-08-27
EP0573510A1 (de) 1993-12-15
ES2117046T3 (es) 1998-08-01
DE69232579D1 (de) 2002-05-29
DE69224983T2 (de) 1998-07-30
ATE216592T1 (de) 2002-05-15
ATE164521T1 (de) 1998-04-15
ES2174144T3 (es) 2002-11-01
DK0573510T3 (da) 1998-04-27
DK0798002T3 (da) 2002-08-19
JPH06504551A (ja) 1994-05-26
CA2100876A1 (en) 1992-07-18
EP0798002A1 (de) 1997-10-01
JP2002316945A (ja) 2002-10-31
EP0798002B1 (de) 2002-04-24
US5648076A (en) 1997-07-15
AU665529B2 (en) 1996-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee