ES2174144T3 - Anticuerpos contra el factor de crecimiento derivado de plaquetas en el tratamiento de la reestenosis. - Google Patents
Anticuerpos contra el factor de crecimiento derivado de plaquetas en el tratamiento de la reestenosis.Info
- Publication number
- ES2174144T3 ES2174144T3 ES97106298T ES97106298T ES2174144T3 ES 2174144 T3 ES2174144 T3 ES 2174144T3 ES 97106298 T ES97106298 T ES 97106298T ES 97106298 T ES97106298 T ES 97106298T ES 2174144 T3 ES2174144 T3 ES 2174144T3
- Authority
- ES
- Spain
- Prior art keywords
- plates
- reset
- treatment
- growth factor
- antibodies against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003102 growth factor Substances 0.000 title 1
- 206010057469 Vascular stenosis Diseases 0.000 abstract 1
- 210000001367 artery Anatomy 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
METODOS PARA INHIBIR LA ESTENOSIS VASCULAR EN UN MAMIFERO, INCLUYENDO LA RESTENOSIS TRAS LA ELIMINACION QUIRURGICA DE LAS PLACAS ATEROSCLEROTICAS O EL BYPASS QUIRURGICO DE ARTERIAS OCLUIDAS. LA INHIBICION SE CONSIGUE MEDIANTE LA ADMINISTRACION DE ANTICUERPOS ANTI-FACTOR DE CRECIMIENTO, INCLUYENDO LOS ANTICUERPOS ANTI-FGF Y ANTICUERPOS ANTI-PDGF.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64175891A | 1991-01-17 | 1991-01-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2174144T3 true ES2174144T3 (es) | 2002-11-01 |
Family
ID=24573729
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97106298T Expired - Lifetime ES2174144T3 (es) | 1991-01-17 | 1992-01-17 | Anticuerpos contra el factor de crecimiento derivado de plaquetas en el tratamiento de la reestenosis. |
ES92905617T Expired - Lifetime ES2117046T3 (es) | 1991-01-17 | 1992-01-17 | Anticuerpo anti-factor de crecimiento en el tratamiento de estenosis vascular. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92905617T Expired - Lifetime ES2117046T3 (es) | 1991-01-17 | 1992-01-17 | Anticuerpo anti-factor de crecimiento en el tratamiento de estenosis vascular. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5648076A (es) |
EP (2) | EP0798002B1 (es) |
JP (2) | JP3667752B2 (es) |
AT (2) | ATE164521T1 (es) |
AU (1) | AU665529B2 (es) |
CA (1) | CA2100876A1 (es) |
DE (2) | DE69224983T2 (es) |
DK (2) | DK0573510T3 (es) |
ES (2) | ES2174144T3 (es) |
WO (1) | WO1992012734A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5770198A (en) * | 1988-05-18 | 1998-06-23 | The Research Foundation Of The State Of New York | Platelet-specific chimeric 7E3 immunoglobulin |
CN1186439A (zh) * | 1995-06-07 | 1998-07-01 | 森特克公司 | 血小板特异性的嵌合性免疫球蛋白及其使用方法 |
US7241568B2 (en) | 1996-04-03 | 2007-07-10 | Kyowa Hakko Kogyo Co., Ltd. | Anti-fibroblast growth factor-8 monoclonal antibody |
AU6497198A (en) * | 1997-02-14 | 1998-09-08 | Boehringer Mannheim Gmbh | Improved method for the reduction of neointima formation after angioplasty |
EP1422243B1 (en) * | 2001-06-28 | 2008-04-23 | Kyowa Hakko Kogyo Co., Ltd | Humanized antibody against fibroblast growth factor-8 and fragment of the antibody |
PL1680140T3 (pl) * | 2003-10-16 | 2011-11-30 | Imclone Llc | Inhibitory receptora-1 czynnika wzrostu fibroblastów i związane z nim sposoby leczenia |
US9339593B2 (en) * | 2007-01-11 | 2016-05-17 | Robert L. Bjork, JR. | Drug-eluting coronary artery stent coated with anti-platelet-derived growth factor antibodies overlaying extracellular matrix proteins with an outer coating of anti-inflammatory (calcineurin inhibitor) and/or anti-proliferatives |
JP5602432B2 (ja) * | 2007-01-11 | 2014-10-08 | ロバート ラマール ジュニア ビョーク | 経皮的冠動脈インターベンション用の多剤溶出冠動脈ステント |
WO2016149103A1 (en) * | 2015-03-13 | 2016-09-22 | The Regents Of The University Of California | Monoclonal antibody for prevention and/or treatment of astrovirus disease |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE116373T1 (de) * | 1987-03-03 | 1995-01-15 | Takeda Chemical Industries Ltd | Monoklonaler antikörper, hybridomen, ihre herstellung und ihre verwendung. |
CA1339356C (en) * | 1988-02-02 | 1997-08-26 | Lewis T. Williams | Human platelet-derived growth factor receptor |
US5268358A (en) * | 1988-12-08 | 1993-12-07 | Cor Therapeutics, Inc. | PDGF receptor blocking peptides |
AU6605690A (en) * | 1989-10-27 | 1991-05-31 | Du Pont Merck Pharmaceutical Company, The | Monoclonal antibodies to basic fibroblast growth factor that inhibit its biological activity |
JP4350370B2 (ja) * | 2002-12-27 | 2009-10-21 | 株式会社半導体エネルギー研究所 | 電子回路及び電子機器 |
-
1992
- 1992-01-17 ES ES97106298T patent/ES2174144T3/es not_active Expired - Lifetime
- 1992-01-17 AU AU13274/92A patent/AU665529B2/en not_active Ceased
- 1992-01-17 DE DE69224983T patent/DE69224983T2/de not_active Expired - Fee Related
- 1992-01-17 AT AT92905617T patent/ATE164521T1/de not_active IP Right Cessation
- 1992-01-17 WO PCT/US1992/000438 patent/WO1992012734A1/en active IP Right Grant
- 1992-01-17 CA CA002100876A patent/CA2100876A1/en not_active Abandoned
- 1992-01-17 EP EP97106298A patent/EP0798002B1/en not_active Expired - Lifetime
- 1992-01-17 DK DK92905617.4T patent/DK0573510T3/da active
- 1992-01-17 DK DK97106298T patent/DK0798002T3/da active
- 1992-01-17 AT AT97106298T patent/ATE216592T1/de not_active IP Right Cessation
- 1992-01-17 ES ES92905617T patent/ES2117046T3/es not_active Expired - Lifetime
- 1992-01-17 JP JP50537192A patent/JP3667752B2/ja not_active Expired - Fee Related
- 1992-01-17 DE DE69232579T patent/DE69232579T2/de not_active Expired - Fee Related
- 1992-01-17 EP EP92905617A patent/EP0573510B1/en not_active Expired - Lifetime
-
1994
- 1994-07-26 US US08/281,132 patent/US5648076A/en not_active Expired - Fee Related
-
2002
- 2002-03-04 JP JP2002057904A patent/JP2002316945A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO1992012734A1 (en) | 1992-08-06 |
DE69232579T2 (de) | 2002-08-22 |
JP3667752B2 (ja) | 2005-07-06 |
EP0573510B1 (en) | 1998-04-01 |
DE69224983D1 (de) | 1998-05-07 |
AU1327492A (en) | 1992-08-27 |
EP0573510A1 (en) | 1993-12-15 |
ES2117046T3 (es) | 1998-08-01 |
DE69232579D1 (de) | 2002-05-29 |
DE69224983T2 (de) | 1998-07-30 |
ATE216592T1 (de) | 2002-05-15 |
ATE164521T1 (de) | 1998-04-15 |
DK0573510T3 (da) | 1998-04-27 |
DK0798002T3 (da) | 2002-08-19 |
JPH06504551A (ja) | 1994-05-26 |
CA2100876A1 (en) | 1992-07-18 |
EP0798002A1 (en) | 1997-10-01 |
JP2002316945A (ja) | 2002-10-31 |
EP0798002B1 (en) | 2002-04-24 |
US5648076A (en) | 1997-07-15 |
AU665529B2 (en) | 1996-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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