DE69222710D1 - Verfahren zum Nachweis von DNS-Basen mit Verwendung von Fluoreszenz - Google Patents

Verfahren zum Nachweis von DNS-Basen mit Verwendung von Fluoreszenz

Info

Publication number
DE69222710D1
DE69222710D1 DE69222710T DE69222710T DE69222710D1 DE 69222710 D1 DE69222710 D1 DE 69222710D1 DE 69222710 T DE69222710 T DE 69222710T DE 69222710 T DE69222710 T DE 69222710T DE 69222710 D1 DE69222710 D1 DE 69222710D1
Authority
DE
Germany
Prior art keywords
fluorescence
procedure
detection
dna bases
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69222710T
Other languages
English (en)
Other versions
DE69222710T2 (de
Inventor
Shiguru Hosoi
Tsuyoshi Hayakawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hamamatsu Photonics KK
Original Assignee
Hamamatsu Photonics KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hamamatsu Photonics KK filed Critical Hamamatsu Photonics KK
Publication of DE69222710D1 publication Critical patent/DE69222710D1/de
Application granted granted Critical
Publication of DE69222710T2 publication Critical patent/DE69222710T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J43/00—Secondary-emission tubes; Electron-multiplier tubes
    • H01J43/04—Electron multipliers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Photometry And Measurement Of Optical Pulse Characteristics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69222710T 1991-07-23 1992-07-23 Verfahren zum Nachweis von DNS-Basen mit Verwendung von Fluoreszenz Expired - Fee Related DE69222710T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3182478A JPH0526810A (ja) 1991-07-23 1991-07-23 微粒子の螢光検出装置

Publications (2)

Publication Number Publication Date
DE69222710D1 true DE69222710D1 (de) 1997-11-20
DE69222710T2 DE69222710T2 (de) 1998-02-12

Family

ID=16118978

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69222710T Expired - Fee Related DE69222710T2 (de) 1991-07-23 1992-07-23 Verfahren zum Nachweis von DNS-Basen mit Verwendung von Fluoreszenz

Country Status (4)

Country Link
US (1) US5260029A (de)
EP (1) EP0526112B1 (de)
JP (1) JPH0526810A (de)
DE (1) DE69222710T2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3290786B2 (ja) * 1993-11-26 2002-06-10 シスメックス株式会社 粒子分析装置
US5690894A (en) * 1995-05-23 1997-11-25 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor
US5837196A (en) * 1996-01-26 1998-11-17 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor
AT403745B (de) * 1996-02-29 1998-05-25 Avl Verbrennungskraft Messtech Messanordnung mit einem für anregungs- und messstrahlung transparentem trägerelement
US5714388A (en) * 1996-08-14 1998-02-03 Bayer Corporation Apparatus and method for detecting chemiluminescent light
DE19702557C2 (de) * 1997-01-24 1999-06-17 Fraunhofer Ges Forschung Vorrichtung zur Erfassung von diffus emittiertem Licht
AU8148898A (en) * 1997-06-23 1999-01-04 Luminex Corporation Interlaced lasers for multiple fluorescence measurement
JP4215397B2 (ja) * 1998-05-14 2009-01-28 ルミネックス コーポレイション 多重分析物診断システム
AU3771599A (en) 1998-05-18 1999-12-06 University Of Washington Liquid analysis cartridge
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US6355921B1 (en) 1999-05-17 2002-03-12 Agilent Technologies, Inc. Large dynamic range light detection
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
IL162761A (en) * 2004-06-28 2013-04-30 Avraham Shekalim A device for continuous glucose measurement in body fluids
US9500588B2 (en) 2014-09-30 2016-11-22 Perkinelmer Health Sciences, Inc. Flow cell modules and liquid sample analyzers and methods including same
US9581491B2 (en) 2014-09-30 2017-02-28 Perkinelmer Health Sciences, Inc. Flow cell modules and liquid sample analyzers and methods including same

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3849654A (en) * 1973-10-19 1974-11-19 H Malvin Fluorescence cuvette
US4173415A (en) * 1976-08-20 1979-11-06 Science Spectrum, Inc. Apparatus and process for rapidly characterizing and differentiating large organic cells
US4115699A (en) * 1977-06-16 1978-09-19 Kabushiki Kaisha Nihon Kotai Kenkyujo Apparatus for sensitive detection and quantitative analysis of biological and biochemical substances
GB1598779A (en) * 1978-05-25 1981-09-23 Itt Creed Ink-jet printers
DE2943116C2 (de) * 1979-10-25 1986-06-19 Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München Einrichtung zur durchflußcytometrischen Reaktions- und/oder Diffusionsmessung
JPS59174742A (ja) * 1983-03-25 1984-10-03 Agency Of Ind Science & Technol 微小粒子を区分又は選別する方法及びその装置
US4600302A (en) * 1984-03-26 1986-07-15 Becton, Dickinson And Company Flow cytometry apparatus with uniform incoherent light excitation
US4643566A (en) * 1984-07-20 1987-02-17 Canon Kabushiki Kaisha Particle analyzing apparatus
JPH07118294B2 (ja) * 1987-02-13 1995-12-18 浜松ホトニクス株式会社 光電子増倍管
US4855930A (en) * 1987-03-27 1989-08-08 Chimerix Corporation Method and appartatus for improved time-resolved fluorescence spectroscopy
US4867559A (en) * 1988-01-06 1989-09-19 Amoco Corporation Liquid/liquid fiber-optic fluorescence detector and absorbance analyzer
EP0422616B1 (de) * 1989-10-11 1996-02-07 Canon Kabushiki Kaisha Gerät und Verfahren zur Trennung von Teilchen aus flüssigkeitssuspendierten Teilchen in Zusammenhang mit deren Eigenschaften

Also Published As

Publication number Publication date
US5260029A (en) 1993-11-09
EP0526112A3 (en) 1993-11-10
JPH0526810A (ja) 1993-02-02
DE69222710T2 (de) 1998-02-12
EP0526112B1 (de) 1997-10-15
EP0526112A2 (de) 1993-02-03

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee