DE69222031D1 - Lösungsmittelsystem zum einschliessen in kapseln - Google Patents

Lösungsmittelsystem zum einschliessen in kapseln

Info

Publication number
DE69222031D1
DE69222031D1 DE69222031T DE69222031T DE69222031D1 DE 69222031 D1 DE69222031 D1 DE 69222031D1 DE 69222031 T DE69222031 T DE 69222031T DE 69222031 T DE69222031 T DE 69222031T DE 69222031 D1 DE69222031 D1 DE 69222031D1
Authority
DE
Germany
Prior art keywords
capsules
solvent system
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69222031T
Other languages
English (en)
Other versions
DE69222031T2 (de
Inventor
Hirokazu Makino
Ichiro Hakamada
Osamu Yamada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Catalent Pharma Solutions Inc
Original Assignee
Catalent Pharma Solutions Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Catalent Pharma Solutions Inc filed Critical Catalent Pharma Solutions Inc
Publication of DE69222031D1 publication Critical patent/DE69222031D1/de
Application granted granted Critical
Publication of DE69222031T2 publication Critical patent/DE69222031T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/485—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE69222031T 1991-12-19 1992-12-18 Lösungsmittelsystem zum einschliessen in kapseln Expired - Lifetime DE69222031T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP03337138A JP3121080B2 (ja) 1991-12-19 1991-12-19 カプセル封入用溶液
PCT/US1992/010773 WO1993011753A1 (en) 1991-12-19 1992-12-18 Solvent system to be enclosed in capsules

Publications (2)

Publication Number Publication Date
DE69222031D1 true DE69222031D1 (de) 1997-10-09
DE69222031T2 DE69222031T2 (de) 1998-03-26

Family

ID=18305803

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69222031T Expired - Lifetime DE69222031T2 (de) 1991-12-19 1992-12-18 Lösungsmittelsystem zum einschliessen in kapseln

Country Status (9)

Country Link
US (1) US5912011A (de)
EP (1) EP0572627B1 (de)
JP (1) JP3121080B2 (de)
AU (1) AU3278393A (de)
CA (1) CA2103793C (de)
DE (1) DE69222031T2 (de)
ES (1) ES2108255T3 (de)
WO (1) WO1993011753A1 (de)
ZA (1) ZA929854B (de)

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PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
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AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
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US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US20070086952A1 (en) * 2005-09-29 2007-04-19 Biodel, Inc. Rapid Acting and Prolonged Acting Inhalable Insulin Preparations
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EP2497484A3 (de) 2006-02-22 2012-11-07 MannKind Corporation Verfahren zur Verbesserung der pharmazeutischen Eigenschaften von Mikropartikeln mit Diketopiperazin und einem Wirkstoff
MX2008013165A (es) * 2006-04-12 2009-01-29 Biodel Inc Formulaciones de combinacion de insulina de accion rapida y accion larga.
BRPI0713054A2 (pt) * 2006-06-30 2012-04-17 Mcneil Ppc Inc cápsulas sólidas enchidas com lìquido contendo ibuprofeno
WO2009069139A1 (en) * 2007-11-28 2009-06-04 Alkem Laboratories Ltd. Dosage form providing an ibuprofen-containing liquid fill
AU2009204309B2 (en) * 2008-01-04 2012-11-22 Biodel, Inc. Insulin formulations for insulin release as a function of tissue glucose levels
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2570147T3 (da) 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
WO2010011522A1 (en) * 2008-07-21 2010-01-28 Albemarle Corporation High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
US20150250750A1 (en) * 2012-10-16 2015-09-10 Wockhardt Limited Pharmaceutical compostions of diclofenac or salts thereof
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20180071221A1 (en) * 2015-03-02 2018-03-15 Bionpharma Healthcare Llc Immediate release soluble ibuprofen compositions
CN107951857B (zh) * 2017-11-29 2019-12-24 浙江安宝药业有限公司 布洛芬软胶囊
WO2019224832A1 (en) 2018-05-25 2019-11-28 Strides Shasun Limited Process for preparing pharmaceutical compositions resulting in reduction in overall fill volume for use with soft gelatin formulations
GB2595300B (en) * 2020-05-21 2024-03-27 Reckitt Benckiser Health Ltd Novel Formulation
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Also Published As

Publication number Publication date
WO1993011753A1 (en) 1993-06-24
ZA929854B (en) 1994-01-13
CA2103793A1 (en) 1993-06-20
JPH05310566A (ja) 1993-11-22
JP3121080B2 (ja) 2000-12-25
EP0572627A1 (de) 1993-12-08
CA2103793C (en) 1999-12-07
DE69222031T2 (de) 1998-03-26
ES2108255T3 (es) 1997-12-16
US5912011A (en) 1999-06-15
EP0572627B1 (de) 1997-09-03
AU3278393A (en) 1993-07-19

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