DE69215266D1 - Verfahren zur Herstellung von 1H-Benzimidazolen - Google Patents

Verfahren zur Herstellung von 1H-Benzimidazolen

Info

Publication number
DE69215266D1
DE69215266D1 DE69215266T DE69215266T DE69215266D1 DE 69215266 D1 DE69215266 D1 DE 69215266D1 DE 69215266 T DE69215266 T DE 69215266T DE 69215266 T DE69215266 T DE 69215266T DE 69215266 D1 DE69215266 D1 DE 69215266D1
Authority
DE
Germany
Prior art keywords
benzimidazoles
benzimidazol
carboxyphenyl
preparation
reacted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69215266T
Other languages
English (en)
Other versions
DE69215266T2 (de
Inventor
Gysel August Van
Andre Maquestiau
Eynde Jean-Jacques Vanden
Annie Mayence
Jean-Claude Vanovervelt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proviron Fine Chemicals Nv Oostende Be
Original Assignee
UCB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB SA filed Critical UCB SA
Application granted granted Critical
Publication of DE69215266D1 publication Critical patent/DE69215266D1/de
Publication of DE69215266T2 publication Critical patent/DE69215266T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69215266T 1991-04-18 1992-03-30 Verfahren zur Herstellung von 1H-Benzimidazolen Expired - Fee Related DE69215266T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919108279A GB9108279D0 (en) 1991-04-18 1991-04-18 A method of preparing 1h-benzimidazoles

Publications (2)

Publication Number Publication Date
DE69215266D1 true DE69215266D1 (de) 1997-01-02
DE69215266T2 DE69215266T2 (de) 1997-05-28

Family

ID=10693485

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69215266T Expired - Fee Related DE69215266T2 (de) 1991-04-18 1992-03-30 Verfahren zur Herstellung von 1H-Benzimidazolen

Country Status (7)

Country Link
EP (1) EP0511187B1 (de)
AT (1) ATE145398T1 (de)
DE (1) DE69215266T2 (de)
DK (1) DK0511187T3 (de)
ES (1) ES2096740T3 (de)
GB (1) GB9108279D0 (de)
GR (1) GR3022603T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942532A (en) * 1997-09-05 1999-08-24 Ortho Pharmaceutical Corporation 2-substituted phenyl-benzimidazole antibacterial agents
BR0206161A (pt) * 2001-10-19 2005-02-01 Ortho Mcneil Pharm Inc 2-fenil benzimidazóis e imidazo-[4,5]-piridinas como inibidores de cds1/chk2 e adjuvantes para quimioterapia ou terapia por radiação no tratamento de câncer
GB0821913D0 (en) 2008-12-02 2009-01-07 Price & Co Antibacterial compounds
EP2251010A1 (de) 2009-05-08 2010-11-17 Sygnis Bioscience GmbH & Co. KG Verwendungen von Thiabendazol und Derivaten davon zur Behandlung neurologischer Leiden
AR077405A1 (es) 2009-07-10 2011-08-24 Sanofi Aventis Derivados del indol inhibidores de hsp90, composiciones que los contienen y utilizacion de los mismos para el tratamiento del cancer
CN101735152A (zh) * 2009-12-18 2010-06-16 长沙理工大学 2,2'-(1,4-亚苯基)二(苯并咪唑-5-羧酸)及其制备方法
PT2575968E (pt) 2010-06-01 2016-06-20 Summit Therapeutics Plc Compostos para o tratamento de doença associada com clostridium difficile
KR20150039551A (ko) * 2013-10-02 2015-04-10 제이에스알 가부시끼가이샤 경화성 조성물, 경화막 및 그의 형성 방법, 그리고 화합물
CN110272390A (zh) * 2019-07-15 2019-09-24 北京大学 多聚磷酸盐激酶靶向抑制剂p8

Also Published As

Publication number Publication date
EP0511187B1 (de) 1996-11-20
GB9108279D0 (en) 1991-06-05
GR3022603T3 (en) 1997-05-31
DE69215266T2 (de) 1997-05-28
EP0511187A1 (de) 1992-10-28
ATE145398T1 (de) 1996-12-15
ES2096740T3 (es) 1997-03-16
DK0511187T3 (da) 1997-04-07

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: PROVIRON FINE CHEMICALS, N.V., OOSTENDE, BE

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee