DE69209323D1 - Mehrschichttabletten mit gesteuerter wirkstoffabgabe enthaltend sowohl naproxen als auch naproxen natriumsalz - Google Patents
Mehrschichttabletten mit gesteuerter wirkstoffabgabe enthaltend sowohl naproxen als auch naproxen natriumsalzInfo
- Publication number
- DE69209323D1 DE69209323D1 DE69209323T DE69209323T DE69209323D1 DE 69209323 D1 DE69209323 D1 DE 69209323D1 DE 69209323 T DE69209323 T DE 69209323T DE 69209323 T DE69209323 T DE 69209323T DE 69209323 D1 DE69209323 D1 DE 69209323D1
- Authority
- DE
- Germany
- Prior art keywords
- naproxen
- naproxic
- naproxes
- sodium salt
- active substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/937,920 US5609884A (en) | 1992-08-31 | 1992-08-31 | Controlled release naproxen sodium plus naproxen combination tablet |
PCT/US1992/009129 WO1994005277A1 (en) | 1992-08-31 | 1992-11-02 | Multilayer controlled release tablets containing both naproxen and naproxen sodium salt |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69209323D1 true DE69209323D1 (de) | 1996-04-25 |
DE69209323T2 DE69209323T2 (de) | 1996-09-05 |
Family
ID=25470568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69209323T Expired - Fee Related DE69209323T2 (de) | 1992-08-31 | 1992-11-02 | Mehrschichttabletten mit gesteuerter wirkstoffabgabe enthaltend sowohl naproxen als auch naproxen natriumsalz |
Country Status (11)
Country | Link |
---|---|
US (2) | US5609884A (de) |
EP (1) | EP0656776B1 (de) |
JP (1) | JPH08500834A (de) |
AT (1) | ATE135570T1 (de) |
AU (1) | AU2916792A (de) |
CA (1) | CA2143010A1 (de) |
DE (1) | DE69209323T2 (de) |
DK (1) | DK0656776T3 (de) |
ES (1) | ES2084390T3 (de) |
GR (1) | GR3019392T3 (de) |
WO (1) | WO1994005277A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1276689B1 (it) * | 1995-06-09 | 1997-11-03 | Applied Pharma Res | Forma farmaceutica solida ad uso orale |
US8022095B2 (en) | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
DE19715594A1 (de) * | 1997-04-15 | 1998-10-22 | Bayer Ag | Analgetika-Kombination |
EP1792616B1 (de) * | 1997-07-31 | 2009-12-16 | Abbott Respiratory LLC | Zusammensetzung enthaltend einen HMG-CoA-Reduktasehemmer und eine Nikotinsäureverbindung zur Behandlung von Hyperlipidämie |
WO2000004879A1 (en) * | 1998-07-24 | 2000-02-03 | Andrix Pharmaceuticals, Inc. | Granule modulating hydrogel system |
US6645192B2 (en) * | 1998-09-30 | 2003-11-11 | Ivy Animal Health, Inc. | Pellet implant system for immediate and delayed release of antiparasitic drug |
JP2003508430A (ja) * | 1999-08-31 | 2003-03-04 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | トラマドールサッカリナートを含有する徐放性投薬形 |
ES2305977T3 (es) * | 1999-12-28 | 2008-11-01 | Ajinomoto Co., Inc. | Preparacion antidiabetica para administracion oral. |
US6953586B1 (en) * | 2000-06-08 | 2005-10-11 | Ivy Animal Health, Inc. | Growth promoting pharmaceutical implant |
US20030035839A1 (en) * | 2001-05-15 | 2003-02-20 | Peirce Management, Llc | Pharmaceutical composition for both intraoral and oral administration |
CA2363528A1 (en) * | 2001-11-19 | 2003-05-19 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Immediate release tablet containing naproxen sodium |
US6863901B2 (en) * | 2001-11-30 | 2005-03-08 | Collegium Pharmaceutical, Inc. | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration |
US6827946B2 (en) * | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
GB2405146A (en) * | 2002-06-07 | 2005-02-23 | Cortical Pty Ltd | Napthalene derivatives which inhibit the cytokine or biological activity of macrophage migration inhibitory factor (MIF) |
US6830759B2 (en) | 2002-06-28 | 2004-12-14 | Ajinomoto Co., Inc. | Antidiabetic preparation for oral administration |
WO2004028510A1 (en) * | 2002-09-28 | 2004-04-08 | Mcneil-Ppc, Inc. | Delayed release dosage forms |
CA2503121A1 (en) * | 2002-10-25 | 2004-05-13 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
EP1558211A2 (de) * | 2002-10-30 | 2005-08-03 | Pharmacia Corporation | Orale tabletten mit verlängerter freisetzung und verfahren für deren herstellung sowie verwendung derselben |
US20040228918A1 (en) * | 2003-01-02 | 2004-11-18 | Chih-Ming Chen | Granule modulating hydrogel system |
JP5826456B2 (ja) * | 2006-04-26 | 2015-12-02 | アルファファーム ピーティーワイ リミテッド | コーティングされていない分離したユニットおよび延長放出マトリクスを含む制御放出配合物 |
GB0625646D0 (en) * | 2006-12-21 | 2007-01-31 | Jagotec Ag | Improvements in or relating to organic compounds |
EP2120945A1 (de) * | 2007-02-28 | 2009-11-25 | Collegium Pharmaceutical, Inc. | Antihistamin-kombination |
US20080031950A1 (en) * | 2007-04-27 | 2008-02-07 | Nectid Inc. | Novel anelgesic combination |
US20080026054A1 (en) * | 2007-04-27 | 2008-01-31 | Nectid Inc. | Novel anelgesic combination |
GB0714790D0 (en) * | 2007-07-30 | 2007-09-12 | Jagotec Ag | Improvements in or relating to organic compounds |
WO2010009432A1 (en) * | 2008-07-17 | 2010-01-21 | Horizon Therapeutics, Inc. | Nsaid dose unit formulations with h2-receptor antagonists and methods of use |
TWI394594B (zh) * | 2009-03-06 | 2013-05-01 | China Chemical & Pharmaceutical Co Ltd | 錠劑藥學組成物及其製造方法 |
US20110052679A1 (en) * | 2009-08-25 | 2011-03-03 | Pharmaceutics International, Inc. | Solid naproxen concentrates and related dosage forms |
US20130064891A1 (en) * | 2010-05-21 | 2013-03-14 | Ashok Sahoo | Pharmaceutical compositions of nsaid and acid inhibitor |
US9839212B2 (en) | 2015-04-16 | 2017-12-12 | Bio-Lab, Inc. | Multicomponent and multilayer compacted tablets |
AU2016317092A1 (en) * | 2015-09-01 | 2018-04-26 | Wellesley Pharmaceuticals, Llc | Extended, delayed and immediate release formulation method of manufacturing and use thereof |
WO2017062027A1 (en) * | 2015-10-09 | 2017-04-13 | Bayer Healthcare Llc | Modified release formulation of naproxen sodium |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4794112A (en) * | 1982-12-09 | 1988-12-27 | Cooper Stephen A | Acetaminophen/hydroxyzine analgesic combinations |
US4599359A (en) * | 1982-12-09 | 1986-07-08 | Stephen A. Cooper | Hydroxyzine-containing analgesic combinations |
US4571333A (en) * | 1983-06-14 | 1986-02-18 | Syntex (U.S.A.) Inc. | Controlled release naproxen and naproxen sodium tablets |
US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
US4923898A (en) * | 1984-12-26 | 1990-05-08 | Analgesic Associates | Analgesic, anti-inflammatory and skeletal muscle relaxant compositions comprising non-steroidal anti-inflammatory drugs and musculoskeletal relaxants and methods of using same |
DE3522550A1 (de) * | 1985-06-24 | 1987-01-02 | Klinge Co Chem Pharm Fab | Aufspruehbare pharmazeutische zubereitung fuer die topische anwendung |
JPS62103012A (ja) * | 1985-10-23 | 1987-05-13 | Eisai Co Ltd | 多重顆粒 |
IT1200178B (it) * | 1986-07-23 | 1989-01-05 | Alfa Farmaceutici Spa | Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica |
IT1201136B (it) * | 1987-01-13 | 1989-01-27 | Resa Farma | Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive |
SE460945B (sv) * | 1987-01-15 | 1989-12-11 | Lejus Medical Ab | En multipel-unit-dos komposition av furosemid |
GB8724763D0 (en) * | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
IT1215726B (it) * | 1988-01-18 | 1990-02-22 | Alfa Wassermann Spa | Formulazioni galeniche a cessione programmata. |
US5202128A (en) * | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
DE69222006T2 (de) * | 1991-10-30 | 1998-01-22 | Glaxo Group Ltd | Mehrschichtzusammensetzungen enthaltend Histamin- oder Serotonin- Antagonisten |
IT1258143B (it) * | 1992-09-11 | 1996-02-20 | Alfa Wassermann Spa | Compresse a cessione programmata contenenti naproxen |
-
1992
- 1992-08-31 US US07/937,920 patent/US5609884A/en not_active Expired - Fee Related
- 1992-11-02 JP JP6507154A patent/JPH08500834A/ja active Pending
- 1992-11-02 EP EP92923137A patent/EP0656776B1/de not_active Expired - Lifetime
- 1992-11-02 AT AT92923137T patent/ATE135570T1/de not_active IP Right Cessation
- 1992-11-02 WO PCT/US1992/009129 patent/WO1994005277A1/en active IP Right Grant
- 1992-11-02 DE DE69209323T patent/DE69209323T2/de not_active Expired - Fee Related
- 1992-11-02 CA CA002143010A patent/CA2143010A1/en not_active Abandoned
- 1992-11-02 DK DK92923137.1T patent/DK0656776T3/da active
- 1992-11-02 ES ES92923137T patent/ES2084390T3/es not_active Expired - Lifetime
- 1992-11-02 AU AU29167/92A patent/AU2916792A/en not_active Abandoned
-
1995
- 1995-06-01 US US08/457,415 patent/US5756125A/en not_active Expired - Fee Related
-
1996
- 1996-03-21 GR GR960400487T patent/GR3019392T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2143010A1 (en) | 1994-03-17 |
US5609884A (en) | 1997-03-11 |
WO1994005277A1 (en) | 1994-03-17 |
DK0656776T3 (da) | 1996-04-15 |
US5756125A (en) | 1998-05-26 |
ES2084390T3 (es) | 1996-05-01 |
EP0656776A1 (de) | 1995-06-14 |
GR3019392T3 (en) | 1996-06-30 |
JPH08500834A (ja) | 1996-01-30 |
DE69209323T2 (de) | 1996-09-05 |
EP0656776B1 (de) | 1996-03-20 |
ATE135570T1 (de) | 1996-04-15 |
AU2916792A (en) | 1994-03-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69209323D1 (de) | Mehrschichttabletten mit gesteuerter wirkstoffabgabe enthaltend sowohl naproxen als auch naproxen natriumsalz | |
DE3868037D1 (de) | Pharmazeutische zusammensetzung mit verzoegerter wirkstoffabgabe. | |
DE19375061I2 (de) | Hexadecylphosphocolin enthaltende arzneimittel mit antitumorwirkung. | |
MX9706785A (es) | Formas de dosificacion farmaceutica oral que comprenden un inhibidor de la bomba de protones y un agente antiacido o alginato. | |
MX9706768A (es) | Formas de dosificacion efervecente de unidades multiples que contienen inhibidor de la bomba de protones. | |
SE9402431D0 (sv) | New tablet formulation | |
IS4083A (is) | Samsetning lyfjaefna, aðferð til framleiðslu hennar, og notkunar sem lyfja | |
ATE22535T1 (de) | Pharmazeutische zusammensetzungen fuer die kontinuierliche freigabe des wirkstoffes. | |
KR950702827A (ko) | 부프로피온 함유 서방형 정제(sustained release tablets containing bupropion) | |
ES2144516T3 (es) | Preparacion con liberacion controlada que contiene una sal de morfina. | |
SE9401406D0 (sv) | Pharmaceutical products for curing tumourous diseases and process for preparing same | |
DE68909772D1 (de) | Diclofenac-Natrium-Arzneizubereitung mit verlängerter Wirkstoffabgabe. | |
ES2110212T3 (es) | Composicion farmaceutica efervescente que contiene ibuprofeno y su procedimiento de preparacion. | |
DE59400446D1 (de) | Brausesystem mit einem alkali- und/oder metallempfindlichen, pharmazeutischen Wirkstoff, und Verfahren zur Herstellung | |
DE3769707D1 (de) | Therapeutisches system mit geregelter wirkstoffabgabe. | |
DE68909409D1 (de) | Heilmitteldosierung zur verabreichung an fische. | |
DK0710108T3 (da) | Flydende, farmaceutisk præparat til oral anvendelse indeholdende 2-(4-isobutylphenyl)-propionsyre | |
DK0615441T3 (da) | Ibuprofenholdigt lægemiddel til akut brug og dets anvendelse | |
EE04661B1 (et) | Viirus-indutseeritud ssteemse oki ja hingamispuudulikkuse reverseerimine lmfotoksiin-beeta raja blokeerimise abil | |
PH27446A (en) | Compound with gastric acid inhibitory effect | |
ATE247462T1 (de) | Verwendung von metformin gegen die gewichtszunahme, die mit valproat und andere psychotropische arzneimittel verbunden ist | |
ATE129891T1 (de) | Ein ibuprofen enthaltendes retard-arzneimittel und seine verwendung. | |
ATE59551T1 (de) | Feste orale arzneiformen mit gestaffelter wirkung zur verabreichung von wirkstoffen mit geschwuere erzeugender nebenwirkung. | |
GR3024854T3 (en) | Drugs for preventing the development of tolerance during treatment with benzodiazepine-receptor-binding substances. | |
DE3650368D1 (de) | Verwendung von Depogen zur Behandlung von eingeschränktem Blutkreislauf. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |