DK0656776T3 - Flerlagstabletter med reguleret frigivelse indeholdende både naproxen og naproxen-natriumsalt - Google Patents
Flerlagstabletter med reguleret frigivelse indeholdende både naproxen og naproxen-natriumsaltInfo
- Publication number
- DK0656776T3 DK0656776T3 DK92923137.1T DK92923137T DK0656776T3 DK 0656776 T3 DK0656776 T3 DK 0656776T3 DK 92923137 T DK92923137 T DK 92923137T DK 0656776 T3 DK0656776 T3 DK 0656776T3
- Authority
- DK
- Denmark
- Prior art keywords
- naproxen
- controlled release
- sodium salt
- tablets containing
- release tablets
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/937,920 US5609884A (en) | 1992-08-31 | 1992-08-31 | Controlled release naproxen sodium plus naproxen combination tablet |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0656776T3 true DK0656776T3 (da) | 1996-04-15 |
Family
ID=25470568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92923137.1T DK0656776T3 (da) | 1992-08-31 | 1992-11-02 | Flerlagstabletter med reguleret frigivelse indeholdende både naproxen og naproxen-natriumsalt |
Country Status (11)
Country | Link |
---|---|
US (2) | US5609884A (da) |
EP (1) | EP0656776B1 (da) |
JP (1) | JPH08500834A (da) |
AT (1) | ATE135570T1 (da) |
AU (1) | AU2916792A (da) |
CA (1) | CA2143010A1 (da) |
DE (1) | DE69209323T2 (da) |
DK (1) | DK0656776T3 (da) |
ES (1) | ES2084390T3 (da) |
GR (1) | GR3019392T3 (da) |
WO (1) | WO1994005277A1 (da) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1276689B1 (it) * | 1995-06-09 | 1997-11-03 | Applied Pharma Res | Forma farmaceutica solida ad uso orale |
US8022095B2 (en) | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
DE19715594A1 (de) * | 1997-04-15 | 1998-10-22 | Bayer Ag | Analgetika-Kombination |
DK1017390T3 (da) * | 1997-07-31 | 2007-06-11 | Kos Life Sciences Inc | Coated tablet, der omfatter nikotinsyre eller en forbindelse, der metaboliseres til nikotinsyre, i en form med langvarig frigivelse og en HMG-CoA-reduktaseinhibitor i en form med öjeblikkelig frigivelse |
WO2000004879A1 (en) * | 1998-07-24 | 2000-02-03 | Andrix Pharmaceuticals, Inc. | Granule modulating hydrogel system |
US6645192B2 (en) | 1998-09-30 | 2003-11-11 | Ivy Animal Health, Inc. | Pellet implant system for immediate and delayed release of antiparasitic drug |
MXPA02002193A (es) | 1999-08-31 | 2002-09-30 | Gr Nenthal Gmbh | Forma de administracion de accion retardada que contiene sacarinato de tramadol. |
JP4822039B2 (ja) * | 1999-12-28 | 2011-11-24 | 味の素株式会社 | 経口投与用糖尿病薬製剤 |
US6953586B1 (en) * | 2000-06-08 | 2005-10-11 | Ivy Animal Health, Inc. | Growth promoting pharmaceutical implant |
US20030035839A1 (en) * | 2001-05-15 | 2003-02-20 | Peirce Management, Llc | Pharmaceutical composition for both intraoral and oral administration |
CA2363528A1 (en) * | 2001-11-19 | 2003-05-19 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Immediate release tablet containing naproxen sodium |
US6863901B2 (en) * | 2001-11-30 | 2005-03-08 | Collegium Pharmaceutical, Inc. | Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration |
US6827946B2 (en) * | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
US20060106102A1 (en) * | 2002-06-07 | 2006-05-18 | Eric Morand | Napththalene derivatives which inhibit the cytokine or biological activity of microphage migration inhibitory factor (mif) |
US6830759B2 (en) | 2002-06-28 | 2004-12-14 | Ajinomoto Co., Inc. | Antidiabetic preparation for oral administration |
EP1545472B1 (en) * | 2002-09-28 | 2010-12-08 | McNeil-PPC, Inc. | Modified release dosage forms with two cores and an opening |
JP2006506461A (ja) * | 2002-10-25 | 2006-02-23 | コルジウム ファーマシューティカル, インコーポレイテッド | ミルナシプランのパルス型放出組成物 |
JP2006507298A (ja) * | 2002-10-30 | 2006-03-02 | ファルマシア コーポレーション | 経口持続放出型錠剤、ならびにその製造法および使用法 |
US20040228918A1 (en) * | 2003-01-02 | 2004-11-18 | Chih-Ming Chen | Granule modulating hydrogel system |
NZ703464A (en) * | 2006-04-26 | 2016-05-27 | Alphapharm Pty Ltd | Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix |
GB0625646D0 (en) * | 2006-12-21 | 2007-01-31 | Jagotec Ag | Improvements in or relating to organic compounds |
WO2008105920A1 (en) * | 2007-02-28 | 2008-09-04 | Collegium Pharmaceutical, Inc. | Antihistamine combination |
US20080031950A1 (en) * | 2007-04-27 | 2008-02-07 | Nectid Inc. | Novel anelgesic combination |
US20080026054A1 (en) * | 2007-04-27 | 2008-01-31 | Nectid Inc. | Novel anelgesic combination |
GB0714790D0 (en) * | 2007-07-30 | 2007-09-12 | Jagotec Ag | Improvements in or relating to organic compounds |
WO2010009432A1 (en) * | 2008-07-17 | 2010-01-21 | Horizon Therapeutics, Inc. | Nsaid dose unit formulations with h2-receptor antagonists and methods of use |
TWI394594B (zh) * | 2009-03-06 | 2013-05-01 | China Chemical & Pharmaceutical Co Ltd | 錠劑藥學組成物及其製造方法 |
US20110052679A1 (en) * | 2009-08-25 | 2011-03-03 | Pharmaceutics International, Inc. | Solid naproxen concentrates and related dosage forms |
WO2011144994A1 (en) * | 2010-05-21 | 2011-11-24 | Lupin Limited | Pharmaceutical compositions of nsaid and acid inhibitor |
US9839212B2 (en) | 2015-04-16 | 2017-12-12 | Bio-Lab, Inc. | Multicomponent and multilayer compacted tablets |
RU2018111400A (ru) * | 2015-09-01 | 2019-10-03 | УЭЛЛСЛИ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Препарат пролонгированного, отсроченного и немедленного высвобождения, способ его получения и применения |
EP3359139B1 (en) * | 2015-10-09 | 2023-06-07 | Bayer HealthCare LLC | Modified release formulation of naproxen sodium |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4794112A (en) * | 1982-12-09 | 1988-12-27 | Cooper Stephen A | Acetaminophen/hydroxyzine analgesic combinations |
US4599359A (en) * | 1982-12-09 | 1986-07-08 | Stephen A. Cooper | Hydroxyzine-containing analgesic combinations |
US4571333A (en) * | 1983-06-14 | 1986-02-18 | Syntex (U.S.A.) Inc. | Controlled release naproxen and naproxen sodium tablets |
US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
US4923898A (en) * | 1984-12-26 | 1990-05-08 | Analgesic Associates | Analgesic, anti-inflammatory and skeletal muscle relaxant compositions comprising non-steroidal anti-inflammatory drugs and musculoskeletal relaxants and methods of using same |
DE3522550A1 (de) * | 1985-06-24 | 1987-01-02 | Klinge Co Chem Pharm Fab | Aufspruehbare pharmazeutische zubereitung fuer die topische anwendung |
JPS62103012A (ja) * | 1985-10-23 | 1987-05-13 | Eisai Co Ltd | 多重顆粒 |
IT1200178B (it) * | 1986-07-23 | 1989-01-05 | Alfa Farmaceutici Spa | Formulazioni galeniche a cessione programmata contenenti farmaci ad attivita' antiflogistica |
IT1201136B (it) * | 1987-01-13 | 1989-01-27 | Resa Farma | Compressa per uso farmaceutico atta al rilascio in tempi successivi di sostanze attive |
SE460945B (sv) * | 1987-01-15 | 1989-12-11 | Lejus Medical Ab | En multipel-unit-dos komposition av furosemid |
GB8724763D0 (en) * | 1987-10-22 | 1987-11-25 | Aps Research Ltd | Sustained-release formulations |
IT1215726B (it) * | 1988-01-18 | 1990-02-22 | Alfa Wassermann Spa | Formulazioni galeniche a cessione programmata. |
US5202128A (en) * | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
DE69222006T2 (de) * | 1991-10-30 | 1998-01-22 | Glaxo Group Ltd | Mehrschichtzusammensetzungen enthaltend Histamin- oder Serotonin- Antagonisten |
IT1258143B (it) * | 1992-09-11 | 1996-02-20 | Alfa Wassermann Spa | Compresse a cessione programmata contenenti naproxen |
-
1992
- 1992-08-31 US US07/937,920 patent/US5609884A/en not_active Expired - Fee Related
- 1992-11-02 AU AU29167/92A patent/AU2916792A/en not_active Abandoned
- 1992-11-02 CA CA002143010A patent/CA2143010A1/en not_active Abandoned
- 1992-11-02 AT AT92923137T patent/ATE135570T1/de not_active IP Right Cessation
- 1992-11-02 EP EP92923137A patent/EP0656776B1/en not_active Expired - Lifetime
- 1992-11-02 DK DK92923137.1T patent/DK0656776T3/da active
- 1992-11-02 ES ES92923137T patent/ES2084390T3/es not_active Expired - Lifetime
- 1992-11-02 WO PCT/US1992/009129 patent/WO1994005277A1/en active IP Right Grant
- 1992-11-02 JP JP6507154A patent/JPH08500834A/ja active Pending
- 1992-11-02 DE DE69209323T patent/DE69209323T2/de not_active Expired - Fee Related
-
1995
- 1995-06-01 US US08/457,415 patent/US5756125A/en not_active Expired - Fee Related
-
1996
- 1996-03-21 GR GR960400487T patent/GR3019392T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO1994005277A1 (en) | 1994-03-17 |
GR3019392T3 (en) | 1996-06-30 |
DE69209323T2 (de) | 1996-09-05 |
US5609884A (en) | 1997-03-11 |
ES2084390T3 (es) | 1996-05-01 |
ATE135570T1 (de) | 1996-04-15 |
AU2916792A (en) | 1994-03-29 |
CA2143010A1 (en) | 1994-03-17 |
DE69209323D1 (de) | 1996-04-25 |
EP0656776A1 (en) | 1995-06-14 |
US5756125A (en) | 1998-05-26 |
JPH08500834A (ja) | 1996-01-30 |
EP0656776B1 (en) | 1996-03-20 |
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