DE69133054D1 - Verfahren zur modifizierung von dna und zur detektion der wirkungen auf die interaktion von modifizierten polypeptiden und zielsubstraten - Google Patents

Verfahren zur modifizierung von dna und zur detektion der wirkungen auf die interaktion von modifizierten polypeptiden und zielsubstraten

Info

Publication number
DE69133054D1
DE69133054D1 DE69133054T DE69133054T DE69133054D1 DE 69133054 D1 DE69133054 D1 DE 69133054D1 DE 69133054 T DE69133054 T DE 69133054T DE 69133054 T DE69133054 T DE 69133054T DE 69133054 D1 DE69133054 D1 DE 69133054D1
Authority
DE
Germany
Prior art keywords
dna
antibiotic
modified
libraries
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69133054T
Other languages
English (en)
Other versions
DE69133054T2 (de
Inventor
David Botstein
Timothy Palzkill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of DE69133054D1 publication Critical patent/DE69133054D1/de
Application granted granted Critical
Publication of DE69133054T2 publication Critical patent/DE69133054T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE69133054T 1990-10-22 1991-10-21 Verfahren zur modifizierung von dna und zur detektion der wirkungen auf die interaktion von modifizierten polypeptiden und zielsubstraten Expired - Lifetime DE69133054T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60215890A 1990-10-22 1990-10-22
PCT/US1991/007506 WO1992007090A1 (en) 1990-10-22 1991-10-21 Methods for modifying and detecting the effects on the interaction of modified polypeptides and target substrates

Publications (2)

Publication Number Publication Date
DE69133054D1 true DE69133054D1 (de) 2002-08-08
DE69133054T2 DE69133054T2 (de) 2002-11-14

Family

ID=24410215

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69133054T Expired - Lifetime DE69133054T2 (de) 1990-10-22 1991-10-21 Verfahren zur modifizierung von dna und zur detektion der wirkungen auf die interaktion von modifizierten polypeptiden und zielsubstraten

Country Status (8)

Country Link
US (1) US5677153A (de)
EP (1) EP0555357B1 (de)
AT (1) ATE220113T1 (de)
CA (1) CA2094495C (de)
DE (1) DE69133054T2 (de)
DK (1) DK0555357T3 (de)
ES (1) ES2179818T3 (de)
WO (1) WO1992007090A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6500660B1 (en) * 1996-11-27 2002-12-31 Université Catholique de Louvain Chimeric target molecules having a regulatable activity
JP4294740B2 (ja) * 1997-05-23 2009-07-15 ソレクサ・インコーポレイテッド 分析物の系列的プロセシングのためのシステムおよび装置
US6054276A (en) 1998-02-23 2000-04-25 Macevicz; Stephen C. DNA restriction site mapping
KR100391884B1 (en) * 2002-07-04 2003-09-06 Amicogen Co Ltd Random codon based mutagenesis using transposon
US20040191873A1 (en) * 2003-03-27 2004-09-30 Won-Bin Young Method for high throughput elucidation of transcriptional profiles and genome annotation
US7323303B2 (en) * 2003-03-31 2008-01-29 Hong Kong Polytechnic University Modified β-lactamases and uses thereof
US7618778B2 (en) * 2004-06-02 2009-11-17 Kaufman Joseph C Producing, cataloging and classifying sequence tags
WO2006069099A2 (en) * 2004-12-21 2006-06-29 Genecopoeia, Inc. Method and compositions for rapidly modifying clones
CN101805747B (zh) * 2010-04-06 2012-05-09 东华大学 一种重复模块基因拼接方法
WO2014039662A1 (en) * 2012-09-07 2014-03-13 Alexander Gubin Methods and products for mutating nucleotide sequences

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769326A (en) * 1980-02-29 1988-09-06 The Regents Of The University Of California Expression linkers
US4643969A (en) * 1983-07-25 1987-02-17 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4935357A (en) * 1986-02-05 1990-06-19 New England Biolabs, Inc. Universal restriction endonuclease
GB8818150D0 (en) * 1988-07-29 1988-09-01 Crc Technology Gene modification
ES2187598T3 (es) * 1989-09-20 2003-06-16 Abbott Lab Metodos para producir proteinas de fusion.

Also Published As

Publication number Publication date
EP0555357A1 (de) 1993-08-18
EP0555357A4 (en) 1996-10-09
ATE220113T1 (de) 2002-07-15
ES2179818T3 (es) 2003-02-01
DE69133054T2 (de) 2002-11-14
WO1992007090A1 (en) 1992-04-30
CA2094495C (en) 2007-04-03
EP0555357B1 (de) 2002-07-03
US5677153A (en) 1997-10-14
CA2094495A1 (en) 1992-04-23
DK0555357T3 (da) 2002-10-28

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