DE69131847T2 - Verwendung von kupfer enthaltenden wirkstoffen zur beschleunigung der wundheilung - Google Patents

Verwendung von kupfer enthaltenden wirkstoffen zur beschleunigung der wundheilung

Info

Publication number
DE69131847T2
DE69131847T2 DE69131847T DE69131847T DE69131847T2 DE 69131847 T2 DE69131847 T2 DE 69131847T2 DE 69131847 T DE69131847 T DE 69131847T DE 69131847 T DE69131847 T DE 69131847T DE 69131847 T2 DE69131847 T2 DE 69131847T2
Authority
DE
Germany
Prior art keywords
copper
accelerate
wounds healing
wounds
healing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131847T
Other languages
English (en)
Other versions
DE69131847D1 (de
Inventor
Loren Pickart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procyte Corp
Original Assignee
Procyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procyte Corp filed Critical Procyte Corp
Publication of DE69131847D1 publication Critical patent/DE69131847D1/de
Application granted granted Critical
Publication of DE69131847T2 publication Critical patent/DE69131847T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/34—Copper; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
DE69131847T 1990-03-26 1991-03-26 Verwendung von kupfer enthaltenden wirkstoffen zur beschleunigung der wundheilung Expired - Fee Related DE69131847T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/499,606 US5164367A (en) 1990-03-26 1990-03-26 Method of using copper(ii) containing compounds to accelerate wound healing
PCT/US1991/002028 WO1991014437A2 (en) 1990-03-26 1991-03-26 Use of copper(ii) containing compounds to accelerate wound healing

Publications (2)

Publication Number Publication Date
DE69131847D1 DE69131847D1 (de) 2000-01-20
DE69131847T2 true DE69131847T2 (de) 2000-04-27

Family

ID=23985940

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131847T Expired - Fee Related DE69131847T2 (de) 1990-03-26 1991-03-26 Verwendung von kupfer enthaltenden wirkstoffen zur beschleunigung der wundheilung

Country Status (8)

Country Link
US (1) US5164367A (de)
EP (1) EP0522004B1 (de)
JP (1) JPH05505808A (de)
AT (1) ATE187646T1 (de)
AU (1) AU7565091A (de)
CA (1) CA2078347C (de)
DE (1) DE69131847T2 (de)
WO (1) WO1991014437A2 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX172248B (es) * 1989-12-20 1993-12-09 Univ Mexico Procedimiento para la obtencion de nuevos complejos aminoacidatos de cobre mixtos a base de fenantrolinas feniladas como agentes anticancerigenos
US5382431A (en) * 1992-09-29 1995-01-17 Skin Biology, Inc. Tissue protective and regenerative compositions
AU2196195A (en) * 1994-03-28 1995-10-17 Skin Biology, Inc. Metal complexes of aloe extracts for skin and hair
CA2186448A1 (en) * 1994-03-28 1995-10-05 Loren R. Pickart Starch-metal complexes for skin and hair
AU2198995A (en) * 1994-03-28 1995-10-17 Skin Biology, Inc. Allantoin-metal complexes for skin and hair
JPH07316192A (ja) * 1994-05-27 1995-12-05 Hoechst Japan Ltd Ｌ−リシル−グリシル−ｌ−ヒスチジンおよびこれを含有する創傷治療剤
US5656588A (en) * 1994-07-19 1997-08-12 Wake Forest University Wound healing formula
ES2081771B1 (es) * 1994-08-05 1996-10-01 Arredondo Javier Olaechea Composicion de un producto liquido de uso topico para quemaduras y golpes.
US5888522A (en) * 1996-08-23 1999-03-30 Skin Biology, Inc. Tissue protective and regenerative compositions
US6096861A (en) * 1997-03-18 2000-08-01 The Regents Of The University Of California Peptide-peptoid metal complexes
US20030130185A1 (en) * 2000-09-29 2003-07-10 David Bar-Or Metal-binding compounds and uses therefor
EP2327713A1 (de) 1999-10-01 2011-06-01 DMI Biosciences, Inc. Metall bindende Verbindungen und ihre Verwendungen
US7592304B2 (en) 1999-10-01 2009-09-22 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US7632803B2 (en) 1999-10-01 2009-12-15 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
US20030166510A1 (en) * 2000-10-11 2003-09-04 Pickart Loren R. Methods and compositions for increasing skin remodeling
US20030148927A1 (en) * 2001-10-05 2003-08-07 Procyte Corporation Stable solutions of peptide copper complexes and cosmetic and pharmaceutical formulations produced therefrom
US20050209131A1 (en) * 2001-11-16 2005-09-22 Singleton Laura C Composition containing peptides complexed with a copper ion
AU2003247816A1 (en) * 2002-07-02 2004-01-23 Procyte Corporation Compositions containing peptide copper complexes and soft tissue fillers
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
KR101108439B1 (ko) 2002-10-25 2012-01-31 포믹스 리미티드 화장료 및 약제용 거품제
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US20040142853A1 (en) * 2002-11-07 2004-07-22 Procyte Corporation Stimulation of hair growth by compositions containing peptide copper complexes and minoxidil
US20040197319A1 (en) * 2003-03-24 2004-10-07 Paul Harch Wound healing composition derived from low platelet concentration plasma
US7128923B2 (en) * 2003-03-31 2006-10-31 Procyte Corporation Preserved and stable compositions containing peptide copper complexes and method related thereto
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US6927205B2 (en) * 2003-04-28 2005-08-09 Procyte Corporation Compositions and methods for treatment of psoriasis
KR20060014433A (ko) * 2003-06-04 2006-02-15 에버사이츠, 엘엘씨 신규의 피부의학 조성물
US6927206B2 (en) * 2003-06-06 2005-08-09 Procyte Corporation Compositions and methods for treatment of rosacea
US20060246047A1 (en) * 2003-06-24 2006-11-02 Masaya Imoto Peptide wirh apoptosis-inhibiting activity
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US20050260275A1 (en) * 2004-04-01 2005-11-24 Procyte Corporation Encapsulated peptide copper complexes and compositions and methods related thereto
WO2006023465A1 (en) * 2004-08-18 2006-03-02 Procyte Corporation Polyethylene glycol-peptide copper complexes and compositions and methods related thereto
KR20070112289A (ko) * 2005-03-16 2007-11-22 프로사이트 코포레이션 노화 또는 광손상된 피부를 예방하고 치료하기 위한 방법및 조성물
WO2007089267A1 (en) 2006-02-03 2007-08-09 Jr Chem, Llc Anti-aging treatment using copper and zinc compositions
US7897800B2 (en) 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
WO2007087738A1 (de) * 2006-02-03 2007-08-09 Pentapharm Ag Biologisch aktive tripeptide, deren kupferkomplexe und salze
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
ES2283212B1 (es) * 2006-03-31 2008-08-16 Lipotec S.A. Peptidos sinteticos utiles en el tratamiento de la piel y su uso en composiciones cosmeticas o dermofarmaceuticas.
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
AU2009205314A1 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
CA2750636C (en) 2009-01-23 2017-07-25 Jr Chem, Llc Rosacea treatments and kits for performing them
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US8871184B2 (en) 2009-10-02 2014-10-28 Foamix Ltd. Topical tetracycline compositions
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders
US9586989B1 (en) 2011-04-12 2017-03-07 Skin Biology, Inc. Non-toxic skin cancer therapy with copper peptides
US10398733B2 (en) 2013-03-15 2019-09-03 Cda Research Group, Inc. Topical copper ion treatments and methods of treatment using topical copper ion treatments in the dermatological areas of the body
US11007143B2 (en) 2013-03-15 2021-05-18 Cda Research Group, Inc. Topical copper ion treatments and methods of treatment using topical copper ion treatments in the oral-respiratory-otic areas of the body
US11000545B2 (en) 2013-03-15 2021-05-11 Cda Research Group, Inc. Copper ion compositions and methods of treatment for conditions caused by coronavirus and influenza
US11318089B2 (en) 2013-03-15 2022-05-03 Cda Research Group, Inc. Topical copper ion treatments and methods of making topical copper ion treatments for use in various anatomical areas of the body
US11083750B2 (en) * 2013-03-15 2021-08-10 Cda Research Group, Inc. Methods of treatment using topical copper ion formulations
GB201507002D0 (en) * 2015-04-24 2015-06-10 Medical Res Council Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents
WO2017049529A1 (en) 2015-09-24 2017-03-30 Innolife Co., Ltd. A pharmaceutical composition comprising a copper chelating tetramine and the use thereof
US10398641B2 (en) 2016-09-08 2019-09-03 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
US11193184B2 (en) 2019-02-22 2021-12-07 Cda Research Group, Inc. System for use in producing a metal ion suspension and process of using same
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
US10898724B2 (en) 2019-06-11 2021-01-26 Soletluna Holdings, Inc. Wearable phototherapy apparatus with anti-viral and other effects
US10716953B1 (en) * 2019-06-11 2020-07-21 Soletluna Holdings, Inc. Wearable phototherapy apparatus

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3194732A (en) * 1960-10-03 1965-07-13 Neuhauser Irene Assisting healing of skin-denuded areas on the body with dried non-fibrous egg-shellmembrane products and compositions therefor
US3558770A (en) * 1967-09-01 1971-01-26 Kraftco Corp Wound treating composition employing an enzyme modified casein
US3551554A (en) * 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
US3767784A (en) * 1970-12-01 1973-10-23 S Gluck Composition for the protection and treatment of injured body tissue and method of utilizing the same
US3758682A (en) * 1972-03-23 1973-09-11 Diagnostics Data Inc Pharmaceutical compositions comprising orgotein and their use
US3832338A (en) * 1972-03-23 1974-08-27 Diagnostic Data Inc Orgotein production using a buffer solution containing divalent metal salts
US4022888A (en) * 1975-09-09 1977-05-10 Diagnostic Data, Inc. Esterified orgotein
DE2700043C2 (de) * 1977-01-03 1983-12-08 Thera Gesellschaft für Patentverwertung mbH, 8036 Herrsching Mittel zur Verbesserung der Durchblutung und Wundheilung
US4167945A (en) * 1977-01-31 1979-09-18 Gottlieb Sheldon K Method for enhancing the healing of grafted tissue
US4287184A (en) * 1977-11-23 1981-09-01 The Massachusetts General Hospital Process for healing wounds
US4263428A (en) * 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
US4440788A (en) * 1980-05-13 1984-04-03 Mitsubishi Chemical Industries, Limited Cysteine derivatives
US4461724A (en) * 1981-10-28 1984-07-24 Nippon Zoki Pharmaceutical Co., Ltd. Peptide compounds, a process for manufacturing them, pharmaceutical compositions containing them, and methods for treating ulcer and thrombus with them
HU193289B (en) * 1984-06-19 1987-09-28 Universal Vegyipari Szoevetkez Cosmetical composition for treating hair and nail containing blood plasma concentrate as active agent
US4937230A (en) * 1985-01-24 1990-06-26 Procyte Corporation Method of healing wounds in horses
US4760051A (en) * 1985-01-24 1988-07-26 Pickart Loren R Use of GHL-Cu as a wound-healing and anti-inflammatory agent
US4665054A (en) * 1985-02-08 1987-05-12 Bioheal, Inc. Chemical derivatives of GHL-Cu
US4767753A (en) * 1985-02-08 1988-08-30 Procyte Corporation Methods and compositions for preventing ulcers
US4810693A (en) * 1985-02-08 1989-03-07 Procyte Corporation Method for inducing biological coverings in wounds
ATE103608T1 (de) * 1987-04-20 1994-04-15 Procyte Corp Chemische derivate von ghl-cu.
WO1988008715A1 (en) * 1987-05-11 1988-11-17 Procyte Corporation Method of tumor inhibition in warm-blooded animals
WO1988008695A1 (en) * 1987-05-11 1988-11-17 Procyte Corporation Methods for stimulating hair growth

Also Published As

Publication number Publication date
CA2078347A1 (en) 1991-09-27
CA2078347C (en) 1996-07-02
ATE187646T1 (de) 2000-01-15
DE69131847D1 (de) 2000-01-20
US5164367A (en) 1992-11-17
EP0522004A1 (de) 1993-01-13
EP0522004B1 (de) 1999-12-15
JPH05505808A (ja) 1993-08-26
WO1991014437A3 (en) 1991-11-28
WO1991014437A2 (en) 1991-10-03
AU7565091A (en) 1991-10-21

Similar Documents

Publication Publication Date Title
DE69131847D1 (de) Verwendung von kupfer enthaltenden wirkstoffen zur beschleunigung der wundheilung
NZ227787A (en) Peptides and compositions having growth hormone regulatory effects
MX164966B (es) Composicion para la cicatrizacion de heridas derivada de plaquetas y un factor alfa de crecimiento y metodo para prepararla
SE8204064D0 (sv) Gewebeklebstoff sowie verfahren zu dessen herstellung
ATE79763T1 (de) Verwendung von mindestens ein cytokin zur herstellung eines arzneimittels zur systemischen behandlung von praeneoplastischen laesionen.
ATE212554T1 (de) Gewebeabdeckung und wachstumsfaktor enthaltende verbindungen zur förderung beschleunigter wundheilung
JPS562962A (en) Glycolic acid oxidase inhibitor 44substitutedd33hydroxyy33pyrolinee2*55done
ATE89740T1 (de) Verfahren zur herstellung und zusammensetzungen von kollagen-derivaten.
ATE90573T1 (de) Verfahren zum stabilisieren von menschlichen albuminloesungen und so erhaltene loesung.
DE69010162D1 (de) Zusammensetzung zur Behandlung von Entzündung.
DE69102401D1 (de) Verfahren zur Herstellung von kappa-Casein-Glycomakropeptid.
DE3874019D1 (de) Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben.
FI894303A0 (fi) Menetelmä veren hyytymistekijöiden stabiloimiseksi
DE68918217D1 (de) Familie von modifizierten Antikörpern mit hoher Affinität zur Behandlung von Krebs.
ATA903489A (de) Protoporphyrinogeninhibitoren und deren verwendung in zusammensetzungen zur erkennung und behandlung von tumoren
ES2079068T3 (es) 2-amino-6-fenil-4h-piran-4-onas antiateroscleroticas y antitromboticas.
ATE5175T1 (de) Verfahren zur stabilisierung von interferon und es enthaltende zusammensetzung.
FI101597B1 (fi) Menetelmä kylmäkuivatun koostumuksen valmistamiseksi käytettäväksi potilaan valodynaamisessa hoidossa tai diagnosoinnissa
ATE53302T1 (de) Mittel zur behandlung von wunden.
ES2073391T3 (es) Metodo y composiciones terapeuticas para el tratamiento de trastornos de perdidas de sangre.
ATE202787T1 (de) Makroskopisch orientiertes zelladhäsionsprotein zur wundbehandlung
ATE59780T1 (de) Pharmazeutische zusammensetzung zur behandlung von tumoren.
ATE25969T1 (de) 1,7-diphenyl-3-methylaza-7-cyan-8-methyl-nonan zur verwendung bei der bekaempfung von krankheiten.
DE3577550D1 (de) Aminocarbonsaeurekomplexe zur behandlung von knochentumoren.
ATE45675T1 (de) Verwendung von interferon gamma (ifn-gamma) zur herstellung von praeparationen zur behandlung rheumatischer erkrankungen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee