DE69130869T2 - Xanthinderivate - Google Patents

Xanthinderivate

Info

Publication number
DE69130869T2
DE69130869T2 DE69130869T DE69130869T DE69130869T2 DE 69130869 T2 DE69130869 T2 DE 69130869T2 DE 69130869 T DE69130869 T DE 69130869T DE 69130869 T DE69130869 T DE 69130869T DE 69130869 T2 DE69130869 T2 DE 69130869T2
Authority
DE
Germany
Prior art keywords
represents hydrogen
different
same
formula
xantine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69130869T
Other languages
English (en)
Other versions
DE69130869D1 (en
Inventor
Fumio Suzuki
Junichi Shimada
Akio Ishii
Hiromi Nonaka
Nobuo Kosaka
Shunji Ichikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE69130869D1 publication Critical patent/DE69130869D1/de
Publication of DE69130869T2 publication Critical patent/DE69130869T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Led Devices (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69130869T 1990-10-18 1991-10-17 Xanthinderivate Expired - Fee Related DE69130869T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28017190 1990-10-18
PCT/JP1991/001420 WO1992006976A1 (fr) 1990-10-18 1991-10-17 Derive de xanthine

Publications (2)

Publication Number Publication Date
DE69130869D1 DE69130869D1 (en) 1999-03-18
DE69130869T2 true DE69130869T2 (de) 1999-06-10

Family

ID=17621294

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130869T Expired - Fee Related DE69130869T2 (de) 1990-10-18 1991-10-17 Xanthinderivate

Country Status (6)

Country Link
EP (1) EP0559893B1 (de)
AT (1) ATE176470T1 (de)
CA (1) CA2094270C (de)
DE (1) DE69130869T2 (de)
ES (1) ES2130138T3 (de)
WO (1) WO1992006976A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484920A (en) * 1992-04-08 1996-01-16 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for Parkinson's disease
CA2093403C (en) * 1992-04-08 1999-08-10 Fumio Suzuki Therapeutic agent for parkinson's disease
JP2928386B2 (ja) * 1992-07-08 1999-08-03 協和醗酵工業株式会社 うつ病治療剤
TW252044B (de) * 1992-08-10 1995-07-21 Boehringer Ingelheim Kg
JP2613355B2 (ja) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 パーキンソン氏病治療剤
CA2112031A1 (en) * 1992-12-24 1994-06-25 Fumio Suzuki Xanthine derivatives
AU6781194A (en) * 1993-05-03 1994-11-21 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
ES2070087B1 (es) * 1993-08-13 1996-02-16 Pfizer Derivados de indol
US5703085A (en) * 1994-02-23 1997-12-30 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
ATE325610T1 (de) 1997-09-05 2006-06-15 Kyowa Hakko Kogyo Kk Xanthinderivative zur behandlung von hirnischämie
EP1300147A1 (de) * 1998-01-05 2003-04-09 Eisai Co. Ltd Purinderivate und Adenosin-A2 Rezeptorantagonist als vorbeugendes oder therapeutisches Mittel für Zuckerkrankheitsmellitus
CA2388176C (en) * 1999-10-29 2007-09-25 Kyowa Hakko Kogyo Co., Ltd. Therapeutic agent for eating disorders
FR2804958B1 (fr) * 2000-02-15 2005-07-08 Hoechst Marion Roussel Inc Derives de xanthine, leur procede de preparation et les intermediaires de ce procede, leur application comme medicament et les compositions pharmaceutiques les renfermant
KR101166000B1 (ko) 2002-01-28 2012-07-16 교와 핫꼬 기린 가부시키가이샤 운동성 질환에 걸린 환자의 치료 방법
US20060122198A1 (en) * 2003-06-27 2006-06-08 Kyowa Hakko Kogyo Co., Ltd. Antiepileptic agent
CA2554426C (en) 2004-01-28 2012-10-16 Kyowa Hakko Kogyo Co., Ltd. Agents for treating migraine
ES2273599B1 (es) 2005-10-14 2008-06-01 Universidad De Barcelona Compuestos para el tratamiento de la fibrilacion auricular.
CA2670788A1 (en) * 2006-12-01 2008-06-12 Cv Therapeutics, Inc. A2a adenosine receptor antagonists
MX2009006346A (es) * 2006-12-22 2010-03-03 Sanol Arznei Schwarz Gmbh Derivados de 8-etinilxantina como antagonistas de receptores de a2a selectivos.
RU2477726C1 (ru) * 2011-10-18 2013-03-20 Общество С Ограниченной Ответственностью "Ньювак" (Ооо "Ньювак") Замещенные феноксиуксусные кислоты, их эфиры и амиды, включающие 2,6-диоксо-2,3,6,7-тетрагидро-1н-пурин-8-иловый фрагмент, - антагонисты аденозинового a2a рецептора и их применение
WO2020125779A1 (en) * 2018-12-21 2020-06-25 Sunshine Lake Pharma Co., Ltd. 8-substituted styryl xanthine derivatives and uses thereof
CN111018856B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CN111072663B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270316A (en) * 1989-10-20 1993-12-14 Kyowa Hakko Kogyo Co., Ltd. Condensed purine derivatives

Also Published As

Publication number Publication date
WO1992006976A1 (fr) 1992-04-30
CA2094270A1 (en) 1992-04-19
CA2094270C (en) 1997-01-21
EP0559893A1 (de) 1993-09-15
ES2130138T3 (es) 1999-07-01
EP0559893B1 (de) 1999-02-03
ATE176470T1 (de) 1999-02-15
DE69130869D1 (en) 1999-03-18
EP0559893A4 (en) 1994-07-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee