DE69128196D1 - Enzymstabilisierung - Google Patents
EnzymstabilisierungInfo
- Publication number
- DE69128196D1 DE69128196D1 DE69128196T DE69128196T DE69128196D1 DE 69128196 D1 DE69128196 D1 DE 69128196D1 DE 69128196 T DE69128196 T DE 69128196T DE 69128196 T DE69128196 T DE 69128196T DE 69128196 D1 DE69128196 D1 DE 69128196D1
- Authority
- DE
- Germany
- Prior art keywords
- enzyme stabilization
- enzyme
- solution
- drying
- mixing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004190 Enzymes Human genes 0.000 title abstract 3
- 108090000790 Enzymes Proteins 0.000 title abstract 3
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
- 229920001448 anionic polyelectrolyte Polymers 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- -1 cyclic polyol Chemical class 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920005862 polyol Polymers 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 230000003019 stabilising effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909006642A GB9006642D0 (en) | 1990-03-24 | 1990-03-24 | Enzyme stabilisation |
PCT/GB1991/000443 WO1991014773A2 (en) | 1990-03-24 | 1991-03-25 | Enzyme stabilisation |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69128196D1 true DE69128196D1 (de) | 1997-12-18 |
DE69128196T2 DE69128196T2 (de) | 1998-05-07 |
DE69128196T3 DE69128196T3 (de) | 2002-07-11 |
Family
ID=10673205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69128196T Expired - Lifetime DE69128196T3 (de) | 1990-03-24 | 1991-03-25 | Enzymstabilisierung |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0523130B2 (de) |
AT (1) | ATE160171T1 (de) |
AU (1) | AU7572091A (de) |
CA (1) | CA2040815C (de) |
DE (1) | DE69128196T3 (de) |
GB (1) | GB9006642D0 (de) |
WO (1) | WO1991014773A2 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9320782D0 (en) * | 1993-10-08 | 1993-12-01 | Univ Leeds Innovations Ltd | Stabilising of proteins on solution |
US6699704B1 (en) | 1994-04-25 | 2004-03-02 | Roche Vitamins Inc. | Heat tolerant phytases |
US6358722B1 (en) | 1994-04-25 | 2002-03-19 | Roche Vitamins, Inc. | Heat tolerant phytases |
CN1159208A (zh) * | 1995-07-28 | 1997-09-10 | 吉斯特·布罗卡迪斯股份有限公司 | 盐稳定化酶制剂 |
CA2231948C (en) | 1997-03-25 | 2010-05-18 | F. Hoffmann-La Roche Ag | Modified phytases |
NZ330940A (en) | 1997-07-24 | 2000-02-28 | F | Production of consensus phytases from fungal origin using computer programmes |
US6451572B1 (en) | 1998-06-25 | 2002-09-17 | Cornell Research Foundation, Inc. | Overexpression of phytase genes in yeast systems |
EP0969089A1 (de) * | 1998-06-29 | 2000-01-05 | F. Hoffmann-La Roche Ag | Phytase-zusammensetzung |
AU760737B2 (en) * | 1998-06-29 | 2003-05-22 | Dsm Ip Assets B.V. | Phytase formulation |
ES2248067T3 (es) | 1999-03-31 | 2006-03-16 | Cornell Research Foundation, Inc. | Fosfatasas con actividad de fitasa mejorada. |
AU2002356880A1 (en) | 2001-10-31 | 2003-05-12 | Phytex, Llc | Phytase-containing animal food and method |
CA2498017C (en) | 2002-09-13 | 2016-06-14 | Cornell Research Foundation, Inc. | Using mutations to improve aspergillus phytases |
RU2418633C2 (ru) | 2004-04-08 | 2011-05-20 | Байоматрика, Инк. | Объединение процессов хранения образцов и управление образцами в медико-биологических науках |
US7919297B2 (en) | 2006-02-21 | 2011-04-05 | Cornell Research Foundation, Inc. | Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase |
WO2008017066A2 (en) | 2006-08-03 | 2008-02-07 | Cornell Research Foundation, Inc. | Phytases with improved thermal stability |
WO2010007431A2 (en) | 2008-07-15 | 2010-01-21 | L3 Technology Limited | Assay test card |
US8519125B2 (en) | 2009-05-11 | 2013-08-27 | Biomatrica, Inc. | Compositions and methods for biological sample storage |
WO2012018638A2 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
US9845489B2 (en) | 2010-07-26 | 2017-12-19 | Biomatrica, Inc. | Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
EP2934572A4 (de) | 2012-12-20 | 2016-11-23 | Biomatrica Inc | Formulierungen und verfahren zur stabilisierung von pcr-reagenzien |
EP3154338B1 (de) | 2014-06-10 | 2020-01-29 | Biomatrica, INC. | Stabilisierung von thrombozyten bei umgebungstemperatur |
EP4242628A3 (de) | 2015-12-08 | 2023-11-08 | Biomatrica, INC. | Verringerung der erythrozytensedimentationsrate |
GB202001501D0 (en) | 2020-02-04 | 2020-03-18 | Fabricnano Ltd | Nucleic acid nanostructures |
GB202007428D0 (en) | 2020-05-19 | 2020-07-01 | Fabricnano Ltd | Polynucleotide synthesis |
GB202110595D0 (en) | 2021-07-22 | 2021-09-08 | Fabricnano Ltd | Functionalised nucleic acid structure |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB995362A (en) * | 1962-05-11 | 1965-06-16 | Smith Kline French Lab | Improvements in or relating to freeze-drying biological material |
JPS5536317B2 (de) * | 1972-04-22 | 1980-09-19 | ||
GB2090599B (en) * | 1981-01-05 | 1984-06-13 | Novo Industri As | Stabilized plasmin compositions and method for preparation thereof |
EP0074237B1 (de) * | 1981-09-01 | 1985-04-24 | JOHN & E STURGE LIMITED | Stabilisierte Laktaselösungen und Verfahren zum Stabilisieren |
JPS601123A (ja) * | 1983-06-17 | 1985-01-07 | Dai Ichi Seiyaku Co Ltd | 外用製剤 |
DK8502857A (de) * | 1984-06-25 | 1985-12-26 | ||
NO852655L (no) * | 1985-06-05 | 1986-12-08 | Bio Data Corp | Fremgangsmaate ved fremstilling av koaguleringsreagens for blodplasma i mikrokonsentrert tablettform. |
US5188825A (en) * | 1989-12-28 | 1993-02-23 | Iles Martin C | Freeze-dried dosage forms and methods for preparing the same |
-
1990
- 1990-03-24 GB GB909006642A patent/GB9006642D0/en active Pending
-
1991
- 1991-03-25 WO PCT/GB1991/000443 patent/WO1991014773A2/en active IP Right Grant
- 1991-03-25 DE DE69128196T patent/DE69128196T3/de not_active Expired - Lifetime
- 1991-03-25 AU AU75720/91A patent/AU7572091A/en not_active Abandoned
- 1991-03-25 EP EP91907277A patent/EP0523130B2/de not_active Expired - Lifetime
- 1991-03-25 AT AT91907277T patent/ATE160171T1/de not_active IP Right Cessation
- 1991-04-19 CA CA002040815A patent/CA2040815C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2040815C (en) | 1996-01-16 |
ATE160171T1 (de) | 1997-11-15 |
WO1991014773A2 (en) | 1991-10-03 |
CA2040815A1 (en) | 1992-10-20 |
EP0523130A1 (de) | 1993-01-20 |
EP0523130B1 (de) | 1997-11-12 |
GB9006642D0 (en) | 1990-05-23 |
DE69128196T3 (de) | 2002-07-11 |
EP0523130B2 (de) | 2001-10-24 |
WO1991014773A3 (en) | 1991-11-14 |
AU7572091A (en) | 1991-10-21 |
DE69128196T2 (de) | 1998-05-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: THE UNIVERSITY OF LEEDS INNOVATIONS LTD., LEEDS, G |
|
8363 | Opposition against the patent | ||
8366 | Restricted maintained after opposition proceedings |