DE69127691T2 - Be-13793c-derivat mit antitumorwirkung - Google Patents

Be-13793c-derivat mit antitumorwirkung

Info

Publication number
DE69127691T2
DE69127691T2 DE69127691T DE69127691T DE69127691T2 DE 69127691 T2 DE69127691 T2 DE 69127691T2 DE 69127691 T DE69127691 T DE 69127691T DE 69127691 T DE69127691 T DE 69127691T DE 69127691 T2 DE69127691 T2 DE 69127691T2
Authority
DE
Germany
Prior art keywords
derivative
antituary
effect
group
monosaccharide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69127691T
Other languages
English (en)
Other versions
DE69127691D1 (de
Inventor
Masanori Okanishi
Daisuke Uemura
Seiichi Tanaka
Katsuhisa Kojiri
Akira Okura
Kohtaro Funaishi
Hiroyuki Suda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Application granted granted Critical
Publication of DE69127691D1 publication Critical patent/DE69127691D1/de
Publication of DE69127691T2 publication Critical patent/DE69127691T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Fats And Perfumes (AREA)
  • Transplanting Machines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE69127691T 1990-05-11 1991-02-20 Be-13793c-derivat mit antitumorwirkung Expired - Fee Related DE69127691T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12229190 1990-05-11
PCT/JP1991/000214 WO1991018003A1 (en) 1990-05-11 1991-02-20 Antitumor be-13793c derivative

Publications (2)

Publication Number Publication Date
DE69127691D1 DE69127691D1 (de) 1997-10-23
DE69127691T2 true DE69127691T2 (de) 1998-01-15

Family

ID=14832324

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69127691T Expired - Fee Related DE69127691T2 (de) 1990-05-11 1991-02-20 Be-13793c-derivat mit antitumorwirkung

Country Status (6)

Country Link
EP (1) EP0528030B1 (de)
JP (1) JP3064416B2 (de)
AT (1) ATE158298T1 (de)
CA (1) CA2082528C (de)
DE (1) DE69127691T2 (de)
WO (1) WO1991018003A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591842A (en) * 1991-11-29 1997-01-07 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5668271A (en) * 1991-11-29 1997-09-16 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5437996A (en) * 1992-11-24 1995-08-01 Banyu Pharmaceutical Co., Ltd. Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives
CN1035878C (zh) * 1992-02-18 1997-09-17 万有制药株式会社 吲哚并吡咯并咔唑衍生物
EP0630242B1 (de) * 1992-03-20 1999-01-20 The Wellcome Foundation Limited Weitere indolderivate mit antiviraler wirkung
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
WO1995030682A1 (fr) * 1994-05-09 1995-11-16 Banyu Pharmaceutical Co., Ltd. Derive d'indolopyrolocarbazole antitumoral
CN1106400C (zh) * 1994-05-09 2003-04-23 万有制药株式会社 抗肿瘤吲哚并吡咯并咔唑衍生物
US5804564A (en) * 1994-05-09 1998-09-08 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
US5922860A (en) * 1994-05-09 1999-07-13 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
ES2206506T3 (es) * 1994-06-13 2004-05-16 Banyu Pharmaceutical Co., Ltd. Gen que codifica glicosil-transferasa, y su utilizacion.
GB9811624D0 (en) * 1998-05-29 1998-07-29 Merck Sharp & Dohme Therapeutic use
WO2004083228A1 (ja) 1999-09-10 2004-09-30 Katsuhisa Kojiri インドロピロロカルバゾール誘導体及び抗腫瘍剤
AU2004272457A1 (en) * 2003-09-16 2005-03-24 Banyu Pharmaceutical Co., Ltd. Novel indolopyrrolocarbazole derivative with antitumor activity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
JP3010675B2 (ja) * 1989-03-23 2000-02-21 萬有製薬株式会社 抗腫瘍性物質ｂｅ―１３７９３ｃ

Also Published As

Publication number Publication date
CA2082528A1 (en) 1991-11-12
WO1991018003A1 (en) 1991-11-28
EP0528030B1 (de) 1997-09-17
EP0528030A4 (en) 1993-03-24
EP0528030A1 (de) 1993-02-24
CA2082528C (en) 2001-03-13
DE69127691D1 (de) 1997-10-23
JP3064416B2 (ja) 2000-07-12
ATE158298T1 (de) 1997-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee