ATE158298T1 - Be-13793c-derivat mit antitumorwirkung - Google Patents

Be-13793c-derivat mit antitumorwirkung

Info

Publication number
ATE158298T1
ATE158298T1 AT91904336T AT91904336T ATE158298T1 AT E158298 T1 ATE158298 T1 AT E158298T1 AT 91904336 T AT91904336 T AT 91904336T AT 91904336 T AT91904336 T AT 91904336T AT E158298 T1 ATE158298 T1 AT E158298T1
Authority
AT
Austria
Prior art keywords
derivative
antitumor effect
group
monosaccharide
monosaccharide group
Prior art date
Application number
AT91904336T
Other languages
English (en)
Inventor
Masanori Okanishi
Daisuke Uemura
Seiichi Tanaka
Katsuhisa Kojiri
Akira Okura
Kohtaro Funaishi
Hiroyuki Suda
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Application granted granted Critical
Publication of ATE158298T1 publication Critical patent/ATE158298T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044—Pyrrole radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Lubricants (AREA)
  • Fats And Perfumes (AREA)
  • Transplanting Machines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT91904336T 1990-05-11 1991-02-20 Be-13793c-derivat mit antitumorwirkung ATE158298T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12229190 1990-05-11

Publications (1)

Publication Number Publication Date
ATE158298T1 true ATE158298T1 (de) 1997-10-15

Family

ID=14832324

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91904336T ATE158298T1 (de) 1990-05-11 1991-02-20 Be-13793c-derivat mit antitumorwirkung

Country Status (6)

Country Link
EP (1) EP0528030B1 (de)
JP (1) JP3064416B2 (de)
AT (1) ATE158298T1 (de)
CA (1) CA2082528C (de)
DE (1) DE69127691T2 (de)
WO (1) WO1991018003A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5437996A (en) * 1992-11-24 1995-08-01 Banyu Pharmaceutical Co., Ltd. Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives
US5668271A (en) * 1991-11-29 1997-09-16 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5591842A (en) * 1991-11-29 1997-01-07 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
CN1035878C (zh) * 1992-02-18 1997-09-17 万有制药株式会社 吲哚并吡咯并咔唑衍生物
ES2125976T3 (es) * 1992-03-20 1999-03-16 Wellcome Found Otros derivados de indol con accion antiviral.
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
WO1995030682A1 (fr) * 1994-05-09 1995-11-16 Banyu Pharmaceutical Co., Ltd. Derive d'indolopyrolocarbazole antitumoral
US5804564A (en) * 1994-05-09 1998-09-08 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
ATE255121T1 (de) * 1994-05-09 2003-12-15 Banyu Pharma Co Ltd Antitumor-indolopyrolocarbazolderivat
US5922860A (en) * 1994-05-09 1999-07-13 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
EP0769555B1 (de) * 1994-06-13 2003-09-03 Banyu Pharmaceutical Co., Ltd. Glycosyltransferase kodierendes gen und seine verwendung
GB9811624D0 (en) * 1998-05-29 1998-07-29 Merck Sharp & Dohme Therapeutic use
WO2004083228A1 (ja) 1999-09-10 2004-09-30 Katsuhisa Kojiri インドロピロロカルバゾール誘導体及び抗腫瘍剤
JPWO2005026185A1 (ja) * 2003-09-16 2006-11-16 萬有製薬株式会社 抗腫瘍性新規インドロピロロカルバゾール誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
JP3010675B2 (ja) * 1989-03-23 2000-02-21 萬有製薬株式会社 抗腫瘍性物質ｂｅ―１３７９３ｃ

Also Published As

Publication number Publication date
WO1991018003A1 (en) 1991-11-28
JP3064416B2 (ja) 2000-07-12
CA2082528C (en) 2001-03-13
CA2082528A1 (en) 1991-11-12
DE69127691T2 (de) 1998-01-15
EP0528030A1 (de) 1993-02-24
EP0528030A4 (en) 1993-03-24
DE69127691D1 (de) 1997-10-23
EP0528030B1 (de) 1997-09-17

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties