ATE158298T1 - Be-13793c-derivat mit antitumorwirkung - Google Patents
Be-13793c-derivat mit antitumorwirkungInfo
- Publication number
- ATE158298T1 ATE158298T1 AT91904336T AT91904336T ATE158298T1 AT E158298 T1 ATE158298 T1 AT E158298T1 AT 91904336 T AT91904336 T AT 91904336T AT 91904336 T AT91904336 T AT 91904336T AT E158298 T1 ATE158298 T1 AT E158298T1
- Authority
- AT
- Austria
- Prior art keywords
- derivative
- antitumor effect
- group
- monosaccharide
- monosaccharide group
- Prior art date
Links
- FETFZHLVPOJEBR-UHFFFAOYSA-N 133805-03-5 Chemical class N1C2=C3NC4=C(O)C=CC=C4C3=C(C(=O)NC3=O)C3=C2C2=C1C(O)=CC=C2 FETFZHLVPOJEBR-UHFFFAOYSA-N 0.000 title 1
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 125000001483 monosaccharide substituent group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/23—Heterocyclic radicals containing two or more heterocyclic rings condensed among themselves or condensed with a common carbocyclic ring system, not provided for in groups C07H19/14 - C07H19/22
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Fats And Perfumes (AREA)
- Transplanting Machines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12229190 | 1990-05-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE158298T1 true ATE158298T1 (de) | 1997-10-15 |
Family
ID=14832324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91904336T ATE158298T1 (de) | 1990-05-11 | 1991-02-20 | Be-13793c-derivat mit antitumorwirkung |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0528030B1 (de) |
| JP (1) | JP3064416B2 (de) |
| AT (1) | ATE158298T1 (de) |
| CA (1) | CA2082528C (de) |
| DE (1) | DE69127691T2 (de) |
| WO (1) | WO1991018003A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5668271A (en) * | 1991-11-29 | 1997-09-16 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
| US5591842A (en) * | 1991-11-29 | 1997-01-07 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
| US5437996A (en) * | 1992-11-24 | 1995-08-01 | Banyu Pharmaceutical Co., Ltd. | Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives |
| CN1035878C (zh) * | 1992-02-18 | 1997-09-17 | 万有制药株式会社 | 吲哚并吡咯并咔唑衍生物 |
| WO1993018766A1 (en) * | 1992-03-20 | 1993-09-30 | The Wellcome Foundation Limited | Further indole derivatives with antiviral activity |
| DE4217964A1 (de) * | 1992-05-30 | 1993-12-02 | Goedecke Ag | Indolocarbazol-Imide und deren Verwendung |
| WO1995030682A1 (en) * | 1994-05-09 | 1995-11-16 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyprolocarbazole derivative |
| ATE283863T1 (de) * | 1994-05-09 | 2004-12-15 | Banyu Pharma Co Ltd | Verfahren zur herstellung von indolopyrrolocarbazol-derivaten |
| US5922860A (en) * | 1994-05-09 | 1999-07-13 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
| US5804564A (en) * | 1994-05-09 | 1998-09-08 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
| DE69531686T2 (de) * | 1994-06-13 | 2004-07-15 | Banyu Pharmaceutical Co., Ltd. | Glycosyltransferase kodierendes gen und seine verwendung |
| JP3536574B2 (ja) | 1997-02-28 | 2004-06-14 | 萬有製薬株式会社 | 抗腫瘍性インドロピロロカルバゾール誘導体 |
| GB9811624D0 (en) * | 1998-05-29 | 1998-07-29 | Merck Sharp & Dohme | Therapeutic use |
| WO2004083228A1 (ja) | 1999-09-10 | 2004-09-30 | Katsuhisa Kojiri | インドロピロロカルバゾール誘導体及び抗腫瘍剤 |
| US20070042975A1 (en) * | 2003-09-16 | 2007-02-22 | Koji Yamada | Novel indolopyrrolocarbazole derivative with antitumor activity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4785085A (en) * | 1986-11-21 | 1988-11-15 | Bristol-Myers Company | Rebeccamycin analogs |
| JP3010675B2 (ja) * | 1989-03-23 | 2000-02-21 | 萬有製薬株式会社 | 抗腫瘍性物質ｂｅ―１３７９３ｃ |
-
1991
- 1991-02-20 AT AT91904336T patent/ATE158298T1/de not_active IP Right Cessation
- 1991-02-20 JP JP3504280A patent/JP3064416B2/ja not_active Expired - Fee Related
- 1991-02-20 CA CA002082528A patent/CA2082528C/en not_active Expired - Fee Related
- 1991-02-20 EP EP91904336A patent/EP0528030B1/de not_active Expired - Lifetime
- 1991-02-20 DE DE69127691T patent/DE69127691T2/de not_active Expired - Fee Related
- 1991-02-20 WO PCT/JP1991/000214 patent/WO1991018003A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0528030A4 (en) | 1993-03-24 |
| DE69127691T2 (de) | 1998-01-15 |
| WO1991018003A1 (fr) | 1991-11-28 |
| CA2082528C (en) | 2001-03-13 |
| JP3064416B2 (ja) | 2000-07-12 |
| EP0528030B1 (de) | 1997-09-17 |
| EP0528030A1 (de) | 1993-02-24 |
| CA2082528A1 (en) | 1991-11-12 |
| DE69127691D1 (de) | 1997-10-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |